Justin Guinney
Justin Guinney
Director of Computational Oncology
Verifierad e-postadress på sagebase.org
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The consensus molecular subtypes of colorectal cancer
J Guinney, R Dienstmann, X Wang, A De Reyniès, A Schlicker, ...
Nature medicine 21 (11), 1350-1356, 2015
20382015
Genome-wide methylation profiles reveal quantitative views of human aging rates
G Hannum, J Guinney, L Zhao, L Zhang, G Hughes, SV Sadda, B Klotzle, ...
Molecular cell 49 (2), 359-367, 2013
14752013
GSVA: gene set variation analysis for microarray and RNA-seq data
S Hänzelmann, R Castelo, J Guinney
BMC bioinformatics 14 (1), 7, 2013
13562013
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
9652018
Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer
R Dienstmann, L Vermeulen, J Guinney, S Kopetz, S Tejpar, J Tabernero
Nature Reviews Cancer 17 (2), 79-92, 2017
4172017
F-Seq: a feature density estimator for high-throughput sequence tags
AP Boyle, J Guinney, GE Crawford, TS Furey
Bioinformatics 24 (21), 2537-2538, 2008
3862008
AACR Project GENIE: powering precision medicine through an international consortium
AACR Project Genie Consortium
Cancer discovery 7 (8), 818-831, 2017
2962017
Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes
FA Sinicrope, Q Shi, TC Smyrk, SN Thibodeau, R Dienstmann, J Guinney, ...
Gastroenterology 148 (1), 88-99, 2015
2592015
Evidence for type II cells as cells of origin of K-Ras–induced distal lung adenocarcinoma
X Xu, JR Rock, Y Lu, C Futtner, B Schwab, J Guinney, BLM Hogan, ...
Proceedings of the National Academy of Sciences 109 (13), 4910-4915, 2012
2042012
Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection
AD Ewing, KE Houlahan, Y Hu, K Ellrott, C Caloian, TN Yamaguchi, ...
Nature methods 12 (7), 623-630, 2015
2032015
Inferring causal molecular networks: empirical assessment through a community-based effort
SM Hill, LM Heiser, T Cokelaer, M Unger, NK Nesser, DE Carlin, Y Zhang, ...
Nature methods 13 (4), 310-318, 2016
1682016
American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine
MW Kattan, KR Hess, MB Amin, Y Lu, KGM Moons, JE Gershenwald, ...
CA: a cancer journal for clinicians 66 (5), 370-374, 2016
1672016
Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data
IS Jang, EC Neto, J Guinney, SH Friend, AA Margolin
Biocomputing 2014, 63-74, 2014
1322014
Genomic strategy for targeting therapy in castration-resistant prostate cancer
P Mendiratta, E Mostaghel, J Guinney, AK Tewari, A Porrello, WT Barry, ...
Journal of clinical oncology 27 (12), 2022-2029, 2009
1272009
CTCF Haploinsufficiency Destabilizes DNA Methylation and Predisposes to Cancer
CJ Kemp, JM Moore, R Moser, B Bernard, M Teater, LE Smith, NA Rabaia, ...
Cell reports 7 (4), 1020-1029, 2014
1082014
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
AA Margolin, E Bilal, E Huang, TC Norman, L Ottestad, BH Mecham, ...
Science translational medicine 5 (181), 181re1-181re1, 2013
1072013
Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open …
J Guinney, T Wang, TD Laajala, KK Winner, JC Bare, EC Neto, SA Khan, ...
The Lancet Oncology 18 (1), 132-142, 2017
1012017
Colorectal cancer consensus molecular subtypes translated to preclinical models uncover potentially targetable cancer cell dependencies
A Sveen, J Bruun, PW Eide, IA Eilertsen, L Ramirez, A Murumägi, ...
Clinical Cancer Research 24 (4), 794-806, 2018
892018
Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
R Dienstmann, MJ Mason, FA Sinicrope, AI Phipps, S Tejpar, ...
Annals of Oncology 28 (5), 1023-1031, 2017
892017
Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles
E Edelman, A Porrello, J Guinney, B Balakumaran, A Bild, PG Febbo, ...
Bioinformatics 22 (14), e108-e116, 2006
892006
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Artiklar 1–20