| VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium DV Bagaev, RMA Vroomans, J Samir, U Stervbo, C Rius, G Dolton, ... Nucleic acids research 48 (D1), D1057-D1062, 2020 | 349 | 2020 |
| Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor A Varela-Rohena, PE Molloy, SM Dunn, Y Li, MM Suhoski, RG Carroll, ... Nature medicine 14 (12), 1390-1395, 2008 | 307 | 2008 |
| Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties B Laugel, HA van den Berg, E Gostick, DK Cole, L Wooldridge, J Boulter, ... Journal of Biological Chemistry 282 (33), 23799-23810, 2007 | 287 | 2007 |
| Human TCR-binding affinity is governed by MHC class restriction DK Cole, NJ Pumphrey, JM Boulter, M Sami, JI Bell, E Gostick, DA Price, ... The Journal of Immunology 178 (9), 5727-5734, 2007 | 275 | 2007 |
| Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies PM Maciocia, PA Wawrzyniecka, B Philip, I Ricciardelli, AU Akarca, ... Nature medicine 23 (12), 1416-1423, 2017 | 250 | 2017 |
| Tricks with tetramers: how to get the most from multimeric peptide–MHC L Wooldridge, A Lissina, DK Cole, HA Van Den Berg, DA Price, AK Sewell Immunology 126 (2), 147-164, 2009 | 247 | 2009 |
| T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ... Immunity 31 (6), 885-896, 2009 | 234 | 2009 |
| Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes AM Bulek, DK Cole, A Skowera, G Dolton, S Gras, F Madura, A Fuller, ... Nature immunology 13 (3), 283-289, 2012 | 220 | 2012 |
| Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance O Stepanek, AS Prabhakar, C Osswald, CG King, A Bulek, D Naeher, ... Cell 159 (2), 333-345, 2014 | 196 | 2014 |
| Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor DK Cole, F Yuan, PJ Rizkallah, JJ Miles, E Gostick, DA Price, GF Gao, ... Journal of Biological Chemistry 284 (40), 27281-27289, 2009 | 171 | 2009 |
| Structural and biophysical determinants of αβ T‐cell antigen recognition JS Bridgeman, AK Sewell, JJ Miles, DA Price, DK Cole Immunology 135 (1), 9-18, 2012 | 165 | 2012 |
| Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity DK Cole, AM Bulek, G Dolton, AJ Schauenberg, B Szomolay, W Rittase, ... The Journal of clinical investigation 126 (6), 2191-2204, 2016 | 164 | 2016 |
| More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers G Dolton, K Tungatt, A Lloyd, V Bianchi, SM Theaker, A Trimby, ... Immunology 146 (1), 11-22, 2015 | 162 | 2015 |
| Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition DK Cole, ESJ Edwards, KK Wynn, M Clement, JJ Miles, K Ladell, ... The Journal of Immunology 185 (4), 2600-2610, 2010 | 160 | 2010 |
| The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy M Legut, DK Cole, AK Sewell Cellular & molecular immunology 12 (6), 656-668, 2015 | 143 | 2015 |
| Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide … J Zhu, G Xiao, Y Xu, F Yuan, C Zheng, Y Liu, H Yan, DK Cole, JI Bell, ... Biochemical and Biophysical Research Communications 319 (1), 283-288, 2004 | 131 | 2004 |
| SARS coronavirus induces apoptosis in Vero E6 cells H Yan, G Xiao, J Zhang, Y Hu, F Yuan, DK Cole, C Zheng, GF Gao Journal of medical virology 73 (3), 323-331, 2004 | 123 | 2004 |
| Peptide length determines the outcome of TCR/peptide-MHCI engagement J Ekeruche-Makinde, JJ Miles, HA Van Den Berg, A Skowera, DK Cole, ... Blood, The Journal of the American Society of Hematology 121 (7), 1112-1123, 2013 | 118 | 2013 |
| Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells G Dolton, A Lissina, A Skowera, K Ladell, K Tungatt, E Jones, ... Clinical & Experimental Immunology 177 (1), 47-63, 2014 | 111 | 2014 |
| The T cell antigen receptor: the Swiss army knife of the immune system M Attaf, M Legut, DK Cole, AK Sewell Clinical & Experimental Immunology 181 (1), 1-18, 2015 | 103 | 2015 |
Andrew SewellDistinguished Research ProfessorVerified email at cardiff.ac.uk
