David Cole
David Cole
Honorary Professor, Cardiff University
Verified email at - Homepage
Cited by
Cited by
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor
A Varela-Rohena, PE Molloy, SM Dunn, Y Li, MM Suhoski, RG Carroll, ...
Nature medicine 14 (12), 1390-1395, 2008
VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium
DV Bagaev, RMA Vroomans, J Samir, U Stervbo, C Rius, G Dolton, ...
Nucleic Acids Research 48 (D1), D1057-D1062, 2020
Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties
B Laugel, HA van den Berg, E Gostick, DK Cole, L Wooldridge, J Boulter, ...
Journal of Biological Chemistry 282 (33), 23799-23810, 2007
Human TCR-binding affinity is governed by MHC class restriction
DK Cole, NJ Pumphrey, JM Boulter, M Sami, JI Bell, E Gostick, DA Price, ...
The Journal of Immunology 178 (9), 5727-5734, 2007
Tricks with tetramers: how to get the most from multimeric peptide–MHC
L Wooldridge, A Lissina, DK Cole, HA Van Den Berg, DA Price, AK Sewell
Immunology 126 (2), 147-164, 2009
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility
OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ...
Immunity 31 (6), 885-896, 2009
Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies
PM Maciocia, PA Wawrzyniecka, B Philip, I Ricciardelli, AU Akarca, ...
Nature medicine 23 (12), 1416-1423, 2017
Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes
AM Bulek, DK Cole, A Skowera, G Dolton, S Gras, F Madura, A Fuller, ...
Nature immunology 13 (3), 283-289, 2012
Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance
O Stepanek, AS Prabhakar, C Osswald, CG King, A Bulek, D Naeher, ...
Cell 159 (2), 333-345, 2014
Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor
DK Cole, F Yuan, PJ Rizkallah, JJ Miles, E Gostick, DA Price, GF Gao, ...
Journal of Biological Chemistry 284 (40), 27281-27289, 2009
Structural and biophysical determinants of αβ T‐cell antigen recognition
JS Bridgeman, AK Sewell, JJ Miles, DA Price, DK Cole
Immunology 135 (1), 9-18, 2012
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
DK Cole, AM Bulek, G Dolton, AJ Schauenberg, B Szomolay, W Rittase, ...
The Journal of clinical investigation 126 (6), 2191-2204, 2016
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition
DK Cole, ESJ Edwards, KK Wynn, M Clement, JJ Miles, K Ladell, ...
The Journal of Immunology 185 (4), 2600-2610, 2010
More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers
G Dolton, K Tungatt, A Lloyd, V Bianchi, SM Theaker, A Trimby, ...
Immunology 146 (1), 11-22, 2015
The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy
M Legut, DK Cole, AK Sewell
Cellular & molecular immunology 12 (6), 656-668, 2015
Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide …
J Zhu, G Xiao, Y Xu, F Yuan, C Zheng, Y Liu, H Yan, DK Cole, JI Bell, ...
Biochemical and Biophysical Research Communications 319 (1), 283-288, 2004
SARS coronavirus induces apoptosis in Vero E6 cells
H Yan, G Xiao, J Zhang, Y Hu, F Yuan, DK Cole, C Zheng, GF Gao
Journal of medical virology 73 (3), 323-331, 2004
Peptide length determines the outcome of TCR/peptide-MHCI engagement
J Ekeruche-Makinde, JJ Miles, HA Van Den Berg, A Skowera, DK Cole, ...
Blood, The Journal of the American Society of Hematology 121 (7), 1112-1123, 2013
Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells
G Dolton, A Lissina, A Skowera, K Ladell, K Tungatt, E Jones, ...
Clinical & Experimental Immunology 177 (1), 47-63, 2014
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection
JJ Miles, AM Bulek, DK Cole, E Gostick, AJA Schauenburg, G Dolton, ...
PLoS pathogens 6 (11), e1001198, 2010
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