| Affibody molecules in biotechnological and medical applications S Ståhl, T Gräslund, AE Karlström, FY Frejd, PÅ Nygren, J Löfblom Trends in biotechnology 35 (8), 691-712, 2017 | 331 | 2017 |
| Improving the tolerance of a protein a analogue to repeated alkaline exposures using a bypass mutagenesis approach M Linhult, S Gülich, T Gräslund, A Simon, M Karlsson, A Sjöberg, K Nord, ... Proteins: structure, function, and bioinformatics 55 (2), 407-416, 2004 | 144 | 2004 |
| Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of γ-globin expression and the … T Gräslund, X Li, L Magnenat, M Popkov, CF Barbas Journal of Biological Chemistry 280 (5), 3707-3714, 2005 | 116 | 2005 |
| S100A4 interacts with p53 in the nucleus and promotes p53 degradation LM Orre, E Panizza, VO Kaminskyy, E Vernet, T Gräslund, B Zhivotovsky, ... Oncogene 32 (49), 5531-5540, 2013 | 107 | 2013 |
| HEHEHE-Tagged Affibody Molecule May Be Purified by IMAC, Is Conveniently Labeled with [99mTc(CO)3]+, and Shows Improved Biodistribution with Reduced … V Tolmachev, C Hofström, J Malmberg, S Ahlgren, SJ Hosseinimehr, ... Bioconjugate chemistry 21 (11), 2013-2022, 2010 | 103 | 2010 |
| Charge engineering of a protein domain to allow efficient ion-exchange recovery T Gräslund, G Lundin, M Uhlén, PÅ Nygren, S Hober Protein Engineering 13 (10), 703-709, 2000 | 86 | 2000 |
| Evolution of programmable zinc finger-recombinases with activity in human cells RM Gordley, JD Smith, T Gräslund, CF Barbas III Journal of molecular biology 367 (3), 802-813, 2007 | 79 | 2007 |
| Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with 99mTc, 111In, and 125I C Hofström, A Orlova, M Altai, F Wångsell, T Gräslund, V Tolmachev Journal of medicinal chemistry 54 (11), 3817-3826, 2011 | 73 | 2011 |
| HAHAHA, HEHEHE, HIHIHI, or HKHKHK: Influence of Position and Composition of Histidine Containing Tags on Biodistribution of [99mTc(CO)3]+-Labeled … C Hofström, M Altai, H Honarvar, J Strand, J Malmberg, ... Journal of medicinal chemistry 56 (12), 4966-4974, 2013 | 71 | 2013 |
| Imaging of insulinlike growth factor type 1 receptor in prostate cancer xenografts using the affibody molecule 111In-DOTA-ZIGF1R: 4551 V Tolmachev, J Malmberg, C Hofström, L Abrahmsén, T Bergman, ... Journal of Nuclear Medicine 53 (1), 90-97, 2012 | 62 | 2012 |
| Protein engineering strategies for selective protein purification M Hedhammar, T Gräslund, S Hober Chemical Engineering & Technology: Industrial Chemistry‐Plant Equipment …, 2005 | 61 | 2005 |
| Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors M Altai, H Liu, H Ding, B Mitran, PH Edqvist, V Tolmachev, A Orlova, ... Journal of controlled release 288, 84-95, 2018 | 60 | 2018 |
| An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein J Seijsing, M Lindborg, I Höidén-Guthenberg, H Bönisch, E Guneriusson, ... Proceedings of the National Academy of Sciences 111 (48), 17110-17115, 2014 | 57 | 2014 |
| Display of active subtilisin 309 on phage: analysis of parameters influencing the selection of subtilisin variants with changed substrate specificity from libraries using … D Legendre, N Laraki, T Gräslund, ME Bjørnvad, M Bouchet, PÅ Nygren, ... Journal of molecular biology 296 (1), 87-102, 2000 | 57 | 2000 |
| Site-specifically conjugated anti-HER2 Affibody® molecules as one-step reagents for target expression analyses on cells and xenograft samples E Lundberg, I Höidén-Guthenberg, B Larsson, M Uhlén, T Gräslund Journal of immunological methods 319 (1-2), 53-63, 2007 | 54 | 2007 |
| Selection of affibody molecules to the ligand‐binding site of the insulin‐like growth factor‐1 receptor J Li, E Lundberg, E Vernet, B Larsson, I Höidén‐Guthenberg, T Gräslund Biotechnology and applied biochemistry 55 (2), 99-109, 2010 | 47 | 2010 |
| [99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours A Orlova, C Hofström, J Strand, Z Varasteh, M Sandstrom, K Andersson, ... European journal of nuclear medicine and molecular imaging 40, 439-449, 2013 | 46 | 2013 |
| In vitro selection of enzymatically active lipase variants from phage libraries using a mechanism-based inhibitor S Danielsen, M Eklund, HJ Deussen, T Gräslund, PÅ Nygren, TV Borchert Gene 272 (1-2), 267-274, 2001 | 46 | 2001 |
| Integrated strategy for selective expanded bed ion-exchange adsorption and site-specific protein processing using gene fusion technology T Gräslund, M Hedhammar, M Uhlén, PÅ Nygren, S Hober Journal of biotechnology 96 (1), 93-102, 2002 | 44 | 2002 |
| In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor J Seijsing, S Yu, FY Frejd, I Höiden-Guthenberg, T Gräslund Scientific Reports 8 (1), 5141, 2018 | 39 | 2018 |
