Zhenyu Yue
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
Z Yue, S Jin, C Yang, AJ Levine, N Heintz
Proceedings of the National Academy of Sciences 100 (25), 15077-15082, 2003
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
M Komatsu, S Waguri, M Koike, Y Sou, T Ueno, T Hara, N Mizushima, ...
Cell 131 (6), 1149-1163, 2007
Molecular definitions of autophagy and related processes
L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ...
The EMBO journal 36 (13), 1811-1836, 2017
Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
G Tang, K Gudsnuk, SH Kuo, ML Cotrina, G Rosoklija, A Sosunov, ...
Neuron 83 (5), 1131-1143, 2014
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
Y Zhong, QJ Wang, X Li, Y Yan, JM Backer, BT Chait, N Heintz, Z Yue
Nature cell biology 11 (4), 468-476, 2009
The Beclin 1–VPS34 complex–at the crossroads of autophagy and beyond
SF Funderburk, QJ Wang, Z Yue
Trends in cell biology 20 (6), 355-362, 2010
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
M Komatsu, QJ Wang, GR Holstein, VL Friedrich Jr, J Iwata, E Kominami, ...
Proceedings of the National Academy of Sciences 104 (36), 14489-14494, 2007
Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues
V Hernández–Gea, Z Ghiassi–Nejad, R Rozenfeld, R Gordon, MI Fiel, ...
Gastroenterology 142 (4), 938-946, 2012
Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience
AK Friedman, JJ Walsh, B Juarez, SM Ku, D Chaudhury, J Wang, X Li, ...
Science 344 (6181), 313-319, 2014
Autophagy in major human diseases
DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ...
The EMBO journal 40 (19), e108863, 2021
Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S
X Li, JC Patel, J Wang, MV Avshalumov, C Nicholson, JD Buxbaum, ...
Journal of Neuroscience 30 (5), 1788-1797, 2010
Induction of autophagy in axonal dystrophy and degeneration
QJ Wang, Y Ding, S Kohtz, N Mizushima, IM Cristea, MP Rout, BT Chait, ...
Journal of Neuroscience 26 (31), 8057-8068, 2006
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations
Z Sheng, S Zhang, D Bustos, T Kleinheinz, CE Le Pichon, SL Dominguez, ...
Science translational medicine 4 (164), 164ra161-164ra161, 2012
A novel protein complex linking the δ2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice
Z Yue, A Horton, M Bravin, PL DeJager, F Selimi, N Heintz
Neuron 35 (5), 921-933, 2002
The Sac1 Domain of SYNJ1 Identified Mutated in a Family with Early‐Onset Progressive Parkinsonism with Generalized Seizures
CE Krebs, S Karkheiran, JC Powell, M Cao, V Makarov, H Darvish, ...
Human mutation 34 (9), 1200-1207, 2013
Leucine‐rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson’s disease R1441C/G mutants
X Li, YC Tan, S Poulose, CW Olanow, XY Huang, Z Yue
Journal of neurochemistry 103 (1), 238-247, 2007
Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain
LG Friedman, ML Lachenmayer, J Wang, L He, SM Poulose, M Komatsu, ...
Journal of Neuroscience 32 (22), 7585-7593, 2012
Autophagy in ischemic stroke
P Wang, BZ Shao, Z Deng, S Chen, Z Yue, CY Miao
Progress in neurobiology 163, 98-117, 2018
Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
KY Hui, H Fernandez-Hernandez, J Hu, A Schaffner, N Pankratz, NY Hsu, ...
Science translational medicine 10 (423), eaai7795, 2018
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