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Nicholas Mitsiades
Nicholas Mitsiades
Chief Translational Officer, Comprehensive Cancer Center, UC Davis Health
Verifierad e-postadress på ucdavis.edu
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Integrative genomic profiling of human prostate cancer
BS Taylor, N Schultz, H Hieronymus, A Gopalan, Y Xiao, BS Carver, ...
Cancer cell 18 (1), 11-22, 2010
40222010
NF-κB as a therapeutic target in multiple myeloma
T Hideshima, D Chauhan, P Richardson, C Mitsiades, N Mitsiades, ...
Journal of Biological Chemistry 277 (19), 16639-16647, 2002
11772002
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
N Mitsiades, CS Mitsiades, PG Richardson, V Poulaki, YT Tai, D Chauhan, ...
Blood, The Journal of the American Society of Hematology 101 (6), 2377-2380, 2003
9342003
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
N Mitsiades, CS Mitsiades, V Poulaki, D Chauhan, G Fanourakis, X Gu, ...
Proceedings of the National Academy of Sciences 99 (22), 14374-14379, 2002
9312002
A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
D Chauhan, L Catley, G Li, K Podar, T Hideshima, M Velankar, ...
Cancer cell 8 (5), 407-419, 2005
8422005
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
N Mitsiades, CS Mitsiades, V Poulaki, D Chauhan, PG Richardson, ...
Blood, The Journal of the American Society of Hematology 99 (12), 4525-4530, 2002
8292002
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
CS Mitsiades, NS Mitsiades, CJ McMullan, V Poulaki, R Shringarpure, ...
Cancer cell 5 (3), 221-230, 2004
7922004
Nonsteroidal anti‐inflammatory drugs prevent early diabetic retinopathy via TNF‐α suppression
A M. Joussen, V Poulaki, N Mitsiades, B Kirchhof, K Koizumi, S Döhmen, ...
The FASEB journal 16 (3), 438-440, 2002
7622002
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
T Hideshima, C Mitsiades, M Akiyama, T Hayashi, D Chauhan, ...
Blood, The Journal of the American Society of Hematology 101 (4), 1530-1534, 2003
7522003
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications
CS Mitsiades, NS Mitsiades, CJ McMullan, V Poulaki, R Shringarpure, ...
Proceedings of the National Academy of Sciences 101 (2), 540-545, 2004
6732004
Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model
R LeBlanc, LP Catley, T Hideshima, S Lentzsch, CS Mitsiades, ...
Cancer research 62 (17), 4996-5000, 2002
6322002
Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications
CS Mitsiades, N Mitsiades, V Poulaki, R Schlossman, M Akiyama, ...
Oncogene 21 (37), 5673-5683, 2002
6242002
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity
N Mitsiades, W Yu, V Poulaki, M Tsokos, I Stamenkovic
Cancer research 61 (2), 577-581, 2001
5412001
Biologic sequelae of nuclear factor–κB blockade in multiple myeloma: therapeutic applications
N Mitsiades, CS Mitsiades, V Poulaki, D Chauhan, PG Richardson, ...
Blood, The Journal of the American Society of Hematology 99 (11), 4079-4086, 2002
5022002
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications
CS Mitsiades, SP Treon, N Mitsiades, Y Shima, P Richardson, ...
Blood, The Journal of the American Society of Hematology 98 (3), 795-804, 2001
5022001
Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal …
AM Joussen, V Poulaki, W Qin, B Kirchhof, N Mitsiades, SJ Wiegand, ...
The American journal of pathology 160 (2), 501-509, 2002
4892002
Antimyeloma activity of heat shock protein-90 inhibition
CS Mitsiades, NS Mitsiades, CJ McMullan, V Poulaki, AL Kung, FE Davies, ...
Blood 107 (3), 1092-1100, 2006
4002006
Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity
DW McMillin, J Delmore, E Weisberg, JM Negri, DC Geer, S Klippel, ...
Nature medicine 16 (4), 483-489, 2010
3722010
Molecular sequelae of histone deacetylase inhibition in human malignant B cells
N Mitsiades, CS Mitsiades, PG Richardson, C McMullan, V Poulaki, ...
Blood, The Journal of the American Society of Hematology 101 (10), 4055-4062, 2003
3682003
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
R LeBlanc, T Hideshima, LP Catley, R Shringarpure, R Burger, ...
Blood 103 (5), 1787-1790, 2004
3482004
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Artiklar 1–20