Clary Clish
Clary Clish
Senior Director, Metabolomics, Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Metabolite profiles and the risk of developing diabetes
TJ Wang, MG Larson, RS Vasan, S Cheng, EP Rhee, E McCabe, ...
Nature medicine 17 (4), 448-453, 2011
23462011
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
19642013
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
K Düvel, JL Yecies, S Menon, P Raman, AI Lipovsky, AL Souza, ...
Molecular cell 39 (2), 171-183, 2010
16102010
Regulation of ferroptotic cancer cell death by GPX4
WS Yang, R SriRamaratnam, ME Welsch, K Shimada, R Skouta, ...
Cell 156 (1-2), 317-331, 2014
15422014
Lipid mediator class switching during acute inflammation: signals in resolution
BD Levy, CB Clish, B Schmidt, K Gronert, CN Serhan
Nature immunology 2 (7), 612-619, 2001
13732001
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2–nonsteroidal antiinflammatory drugs and …
CN Serhan, CB Clish, J Brannon, SP Colgan, N Chiang, K Gronert
The Journal of experimental medicine 192 (8), 1197-1204, 2000
12282000
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
M Jain, R Nilsson, S Sharma, N Madhusudhan, T Kitami, AL Souza, ...
Science 336 (6084), 1040-1044, 2012
10932012
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α
L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ...
Cell 140 (2), 280-293, 2010
8832010
The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes
AD Kostic, D Gevers, H Siljander, T Vatanen, T Hyötyläinen, ...
Cell host & microbe 17 (2), 260-273, 2015
7472015
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
LWS Finley, A Carracedo, J Lee, A Souza, A Egia, J Zhang, ...
Cancer cell 19 (3), 416-428, 2011
7172011
Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages
EM Palsson-McDermott, AM Curtis, G Goel, MAR Lauterbach, FJ Sheedy, ...
Cell metabolism 21 (1), 65-80, 2015
6052015
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ...
Nature medicine 22 (6), 586-597, 2016
5612016
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
J Lloyd-Price, C Arze, AN Ananthakrishnan, M Schirmer, J Avila-Pacheco, ...
Nature 569 (7758), 655-662, 2019
5362019
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
K Birsoy, R Possemato, FK Lorbeer, EC Bayraktar, P Thiru, B Yucel, ...
Nature 508 (7494), 108-112, 2014
5312014
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress
F Vazquez, JH Lim, H Chim, K Bhalla, G Girnun, K Pierce, CB Clish, ...
Cancer cell 23 (3), 287-301, 2013
5192013
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans
EP Rhee, S Cheng, MG Larson, GA Walford, GD Lewis, E McCabe, ...
The Journal of clinical investigation 121 (4), 1402-1411, 2011
4692011
Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer
SM Davidson, T Papagiannakopoulos, BA Olenchock, JE Heyman, ...
Cell metabolism 23 (3), 517-528, 2016
4672016
Metabolite profiling identifies pathways associated with metabolic risk in humans
S Cheng, EP Rhee, MG Larson, GD Lewis, EL McCabe, D Shen, ...
Circulation 125 (18), 2222-2231, 2012
4462012
A synthetic antagonist for the peroxisome proliferator-activated receptor γ inhibits adipocyte differentiation
HM Wright, CB Clish, T Mikami, S Hauser, K Yanagi, R Hiramatsu, ...
Journal of Biological Chemistry 275 (3), 1873-1877, 2000
4292000
Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
JR Mayers, C Wu, CB Clish, P Kraft, ME Torrence, BP Fiske, C Yuan, ...
Nature medicine 20 (10), 1193-1198, 2014
4112014
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