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Margot Thome
Margot Thome
Professor, Faculty of Biology and Medicine, University of Lausanne, Switzerland
Verified email at unil.ch - Homepage
Title
Cited by
Cited by
Year
Inhibition of death receptor signals by cellular FLIP
M Irmler, M Thome, M Hahne, P Schneider, K Hofmann, V Steiner, ...
Nature 388 (6638), 190-195, 1997
34411997
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
N Holler, R Zaru, O Micheau, M Thome, A Attinger, S Valitutti, JL Bodmer, ...
Nature immunology 1 (6), 489-495, 2000
21962000
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
M Thome, P Schneider, K Hofmann, H Fickenscher, E Meinl, F Neipel, ...
Nature 386 (6624), 517-521, 1997
17031997
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB
P Schneider, M Thome, K Burns, JL Bodmer, K Hofmann, T Kataoka, ...
Immunity 7 (6), 831-836, 1997
9261997
The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways
T Kataoka, RC Budd, N Holler, M Thome, F Martinon, M Irmler, K Burns, ...
Current biology 10 (11), 640-648, 2000
7322000
Inhibition of fas death signals by FLIPs
J Tschopp, M Irmler, M Thome
Current opinion in immunology 10 (5), 552-558, 1998
6791998
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
O Micheau, M Thome, P Schneider, N Holler, J Tschopp, DW Nicholson, ...
Journal of Biological Chemistry 277 (47), 45162-45171, 2002
6492002
Regulation of lymphocyte proliferation and death by FLIP
M Thome, J Tschopp
Nature Reviews Immunology 1 (1), 50-58, 2001
5272001
CARMA1, BCL-10 and MALT1 in lymphocyte development and activation
M Thome
Nature Reviews Immunology 4 (5), 348-359, 2004
4962004
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA …
E Aganna, F Martinon, PN Hawkins, JB Ross, DC Swan, DR Booth, ...
Arthritis & Rheumatism 46 (9), 2445-2452, 2002
4372002
CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation
O Gaide, B Favier, DF Legler, D Bonnet, B Brissoni, S Valitutti, C Bron, ...
Nature immunology 3 (9), 836-843, 2002
4262002
Characterization of two receptors for TRAIL
P Schneider, JL Bodmer, M Thome, K Hofmann, N Holler, J Tschopp
FEBS letters 416 (3), 329-334, 1997
4051997
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1
M Thome, K Hofmann, K Burns, F Martinon, JL Bodmer, C Mattmann, ...
Current Biology 8 (15), 885-889, 1998
4031998
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation
T Kataoka, M Schröter, M Hahne, P Schneider, M Irmler, M Thome, ...
The Journal of Immunology 161 (8), 3936-3942, 1998
3941998
TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95)
JL Bodmer, K Burns, P Schneider, K Hofmann, V Steiner, M Thome, ...
Immunity 6 (1), 79-88, 1997
3811997
The proteolytic activity of the paracaspase MALT1 is key in T cell activation
F Rebeaud, S Hailfinger, A Posevitz-Fejfar, M Tapernoux, R Moser, ...
Nature immunology 9 (3), 272-281, 2008
3312008
Requirement for CARMA1 in antigen receptor-induced NF-κB activation and lymphocyte proliferation
T Egawa, B Albrecht, B Favier, MJ Sunshine, K Mirchandani, W O'Brien, ...
Current biology 13 (14), 1252-1258, 2003
3312003
Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell–derived lymphomas
D Vallois, MPD Dobay, RD Morin, F Lemonnier, E Missiaglia, M Juilland, ...
Blood, The Journal of the American Society of Hematology 128 (11), 1490-1502, 2016
2982016
Antigen receptor signaling to NF-κB via CARMA1, BCL10, and MALT1
M Thome, JE Charton, C Pelzer, S Hailfinger
Cold Spring Harbor perspectives in biology 2 (9), a003004, 2010
2872010
Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-κB activation
O Gaide, F Martinon, O Micheau, D Bonnet, M Thome, J Tschopp
FEBS letters 496 (2-3), 121-127, 2001
2812001
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