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Navnath Gavande
Navnath Gavande
Assistant Professor Wayne State University College of Pharmacy, Detroit, Michigan, USA
Verifierad e-postadress på wayne.edu
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DNA repair targeted therapy: The past or future of cancer treatment?
NS Gavande, PS VanderVere-Carozza, HD Hinshaw, SI Jalal, CR Sears, ...
Pharmacology & therapeutics 160, 65-83, 2016
4002016
Modulating DNA repair pathways to improve precision genome engineering
KS Pawelczak, NS Gavande, PS VanderVere-Carozza, JJ Turchi
ACS chemical biology 13 (2), 389-396, 2018
1342018
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor α and-γ (PPARα and γ) dual agonists
N Gavande, A Matin, MS Kim, NX Yang, NK Salam, JR Hanrahan, ...
Journal of medicinal chemistry 52 (21), 6835-6850, 2009
1122009
Regulation of Low‐Density Lipoprotein Receptor and 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Expression by Zingiber officinale in the Liver of High …
S Nammi, MS Kim, NS Gavande, GQ Li, BD Roufogalis
Basic & clinical pharmacology & toxicology 106 (5), 389-395, 2010
852010
The enantiomers of syn-2, 3-difluoro-4-aminobutyric acid elicit opposite responses at the GABA C receptor
I Yamamoto, MJT Jordan, N Gavande, MR Doddareddy, M Chebib, ...
Chemical communications 48 (6), 829-831, 2012
652012
2′‐Methoxy‐6‐methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABAA receptors
N Karim, J Curmi, N Gavande, GAR Johnston, JR Hanrahan, ML Tierney, ...
British journal of pharmacology 165 (4), 880-896, 2012
552012
3-Hydroxy-2′-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABAA receptor subtypes
N Karim, N Gavande, P Wellendorph, GAR Johnston, JR Hanrahan, ...
Biochemical pharmacology 82 (12), 1971-1983, 2011
482011
Structure-based design of highly selective β-secretase inhibitors: synthesis, biological evaluation, and protein–ligand x-ray crystal structure
AK Ghosh, K Venkateswara Rao, ND Yadav, DD Anderson, N Gavande, ...
Journal of medicinal chemistry 55 (21), 9195-9207, 2012
402012
Medicinal chemistry of ρ GABAC receptors
CKL Ng, H Kim, N Gavande, I Yamamoto, RJ Kumar, KN Mewett, ...
Future medicinal chemistry 3 (2), 197-209, 2011
372011
Recent developments in the deoxyfluorination of alcohols and phenols: new reagents, mechanistic insights, and applications
WL Hu, XG Hu, L Hunter
Synthesis 49 (22), 4917-4930, 2017
352017
Insights into the mechanism of inhibition of CXCR4: identification of Piperidinylethanamine analogs as anti-HIV-1 inhibitors
D Das, K Maeda, Y Hayashi, N Gavande, DV Desai, SB Chang, AK Ghosh, ...
Antimicrobial Agents and Chemotherapy 59 (4), 1895-1904, 2015
342015
Novel cyclic phosphinic acids as GABAC ρ receptor antagonists: design, synthesis, and pharmacology
N Gavande, I Yamamoto, NK Salam, TH Ai, PM Burden, GAR Johnston, ...
ACS medicinal chemistry letters 2 (1), 11-16, 2011
342011
Design, Synthesis, and Pharmacological Evaluation of Fluorescent and Biotinylated Antagonists of ρ1 GABAC Receptors
N Gavande, HL Kim, MR Doddareddy, GAR Johnston, M Chebib, ...
ACS Medicinal Chemistry Letters 4 (4), 402-407, 2013
312013
Agonist responses of (R)-and (S)-3-fluoro-γ-aminobutyric acids suggest an enantiomeric fold for GABA binding to GABA C receptors
I Yamamoto, GP Deniau, N Gavande, M Chebib, GAR Johnston, ...
Chemical communications 47 (28), 7956-7958, 2011
292011
Guanidino Acids Act as ρ1 GABAC Receptor Antagonists
M Chebib, N Gavande, KY Wong, A Park, I Premoli, KN Mewett, RD Allan, ...
Neurochemical research 34, 1704-1711, 2009
262009
PROTAC’ing oncoproteins: targeted protein degradation for cancer therapy
JM Kelm, DS Pandey, E Malin, H Kansou, S Arora, R Kumar, NS Gavande
Molecular Cancer 22 (1), 62, 2023
252023
The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia
AN Clarkson, L Boothman-Burrell, Z Dósa, RY Nagaraja, L Jin, K Parker, ...
Journal of Cerebral Blood Flow & Metabolism 39 (7), 1266-1282, 2019
242019
Microwave-enhanced synthesis of 2, 3, 6-trisubstituted pyridazines: application to four-step synthesis of gabazine (SR-95531)
N Gavande, GAR Johnston, JR Hanrahan, M Chebib
Organic & Biomolecular Chemistry 8 (18), 4131-4136, 2010
242010
Design, synthesis, biological evaluation of 3, 5-diaryl-4, 5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via …
G Joshi, M Sharma, S Kalra, NS Gavande, S Singh, R Kumar
Bioorganic Chemistry 107, 104620, 2021
232021
The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists
A Matin, MR Doddareddy, N Gavande, S Nammi, PW Groundwater, ...
Bioorganic & medicinal chemistry 21 (3), 766-778, 2013
232013
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Artiklar 1–20