Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo M Lehmann, M Korfei, K Mutze, S Klee, W Skronska-Wasek, HN Alsafadi, ... European Respiratory Journal 50 (2), 2017 | 337 | 2017 |
Tumor‐propagating cells and Y ap/T az activity contribute to lung tumor progression and metastasis AN Lau, SJ Curtis, CM Fillmore, SP Rowbotham, M Mohseni, DE Wagner, ... The EMBO journal 33 (5), 468-481, 2014 | 241 | 2014 |
Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation … FF Cruz, ZD Borg, M Goodwin, D Sokocevic, DE Wagner, A Coffey, ... Stem cells translational medicine 4 (11), 1302–1316, 2015 | 231 | 2015 |
An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices HN Alsafadi, CA Staab-Weijnitz, M Lehmann, M Lindner, B Peschel, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (6 …, 2017 | 214 | 2017 |
Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue MM De Santis, HN Alsafadi, S Tas, DA Bölükbas, S Prithiviraj, ... Advanced materials 33 (3), 2005476, 2021 | 205 | 2021 |
Comparative decellularization and recellularization of normal versus emphysematous human lungs DE Wagner, NR Bonenfant, CS Parsons, D Sokocevic, EM Brooks, ... Biomaterials 35 (10), 3281-3297, 2014 | 195 | 2014 |
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD HA Baarsma, W Skronska-Wasek, K Mutze, F Ciolek, DE Wagner, ... Journal of Experimental Medicine 214 (1), 143-163, 2017 | 180 | 2017 |
Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis A Martin-Medina, M Lehmann, O Burgy, S Hermann, HA Baarsma, ... American journal of respiratory and critical care medicine 198 (12), 1527-1538, 2018 | 166 | 2018 |
Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures FE Uhl, S Vierkotten, DE Wagner, G Burgstaller, R Costa, I Koch, ... European Respiratory Journal 46 (4), 1150-1166, 2015 | 164 | 2015 |
Three-dimensional scaffolds of acellular human and porcine lungs for high throughput studies of lung disease and regeneration DE Wagner, NR Bonenfant, D Sokocevic, MJ DeSarno, ZD Borg, ... Biomaterials 35 (9), 2664-2679, 2014 | 163 | 2014 |
Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring D Jiang, D Correa-Gallegos, S Christ, A Stefanska, J Liu, P Ramesh, ... Nature cell biology 20 (4), 422-431, 2018 | 159 | 2018 |
Can stem cells be used to generate new lungs? Ex vivo lung bioengineering with decellularized whole lung scaffolds DE Wagner, RW Bonvillain, T Jensen, ED Girard, BA Bunnell, CM Finck, ... Respirology 18 (6), 895-911, 2013 | 130 | 2013 |
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis M Lehmann, L Buhl, HN Alsafadi, S Klee, S Hermann, K Mutze, C Ota, ... Respiratory research 19, 1-12, 2018 | 129 | 2018 |
Inhibition of LTβR signalling activates WNT-induced regeneration in lung TM Conlon, G John-Schuster, D Heide, D Pfister, M Lehmann, Y Hu, ... Nature 588 (7836), 151-156, 2020 | 123 | 2020 |
The effect of age and emphysematous and fibrotic injury on the re-cellularization of de-cellularized lungs D Sokocevic, NR Bonenfant, DE Wagner, ZD Borg, MJ Lathrop, YW Lam, ... Biomaterials 34 (13), 3256-69, 2013 | 117 | 2013 |
Applications and approaches for three-dimensional precision-cut lung slices. Disease modeling and drug discovery HN Alsafadi, FE Uhl, RH Pineda, KE Bailey, M Rojas, DE Wagner, ... American journal of respiratory cell and molecular biology 62 (6), 681-691, 2020 | 115 | 2020 |
The effects of storage and sterilization on de-cellularized and re-cellularized whole lung NR Bonenfant, D Sokocevic, DE Wagner, ZD Borg, MJ Lathrop, YW Lam, ... Biomaterials 34 (13), 3231-3245, 2013 | 115 | 2013 |
Reduced frizzled receptor 4 expression prevents WNT/β-catenin–driven alveolar lung repair in chronic obstructive pulmonary disease W Skronska-Wasek, K Mutze, HA Baarsma, KR Bracke, HN Alsafadi, ... American journal of respiratory and critical care medicine 196 (2), 172-185, 2017 | 104 | 2017 |
Freshly thawed and continuously cultured human bone marrow-derived mesenchymal stromal cells comparably ameliorate allergic airways inflammation in immunocompetent mice FF Cruz, ZD Borg, M Goodwin, D Sokocevic, D Wagner, DH McKenna, ... Stem Cells Translational Medicine 4 (6), 615-624, 2015 | 89 | 2015 |
Acellular human lung scaffolds to model lung disease and tissue regeneration SE Gilpin, DE Wagner European Respiratory Review 27 (148), 2018 | 82 | 2018 |