| Mechanisms linking obesity to insulin resistance and type 2 diabetes SE Kahn, RL Hull, KM Utzschneider Nature 444 (7121), 840-846, 2006 | 6406 | 2006 |
| Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome DB Carr, KM Utzschneider, RL Hull, K Kodama, BM Retzlaff, JD Brunzell, ... Diabetes 53 (8), 2087-2094, 2004 | 1477 | 2004 |
| Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature immunology 11 (10), 897-904, 2010 | 1424 | 2010 |
| Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes RL Hull, GT Westermark, P Westermark, SE Kahn The Journal of clinical endocrinology & metabolism 89 (8), 3629-3643, 2004 | 730 | 2004 |
| The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations: distinct metabolic … M Cnop, MJ Landchild, J Vidal, PJ Havel, NG Knowles, DR Carr, F Wang, ... Diabetes 51 (4), 1005-1015, 2002 | 613 | 2002 |
| Gestational diabetes mellitus increases the risk of cardiovascular disease in women with a family history of type 2 diabetes DB Carr, KM Utzschneider, RL Hull, J Tong, TM Wallace, K Kodama, ... Diabetes care 29 (9), 2078-2083, 2006 | 439 | 2006 |
| β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition CA Jurgens, MN Toukatly, CL Fligner, J Udayasankar, SL Subramanian, ... The American journal of pathology 178 (6), 2632-2640, 2011 | 389 | 2011 |
| The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality SE Kahn, S Zraika, KM Utzschneider, RL Hull Diabetologia 52, 1003-1012, 2009 | 313 | 2009 |
| β-Cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the US CC Jensen, M Cnop, RL Hull, WY Fujimoto, SE Kahn, ... Diabetes 51 (7), 2170-2178, 2002 | 306 | 2002 |
| Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans KM Utzschneider, DB Carr, J Tong, TM Wallace, RL Hull, S Zraika, Q Xiao, ... Diabetologia 48, 2330-2333, 2005 | 260 | 2005 |
| Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis S Zraika, RL Hull, J Udayasankar, K Aston-Mourney, SL Subramanian, ... Diabetologia 52, 626-635, 2009 | 252 | 2009 |
| Progressive loss of β-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes M Cnop, J Vidal, RL Hull, KM Utzschneider, DB Carr, T Schraw, ... Diabetes care 30 (3), 677-682, 2007 | 233 | 2007 |
| Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence? S Zraika, RL Hull, CB Verchere, A Clark, KJ Potter, PE Fraser, DP Raleigh, ... Diabetologia 53, 1046-1056, 2010 | 230 | 2010 |
| Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation RL Hull, K Kodama, KM Utzschneider, DB Carr, RL Prigeon, SE Kahn Diabetologia 48, 1350-1358, 2005 | 175 | 2005 |
| Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet S Andrikopoulos, CM Massa, K Aston-Mourney, A Funkat, BC Fam, ... Journal of Endocrinology 187 (1), 45-53, 2005 | 164 | 2005 |
| Increased dietary fat promotes islet amyloid formation and β-cell secretory dysfunction in a transgenic mouse model of islet amyloid RL Hull, S Andrikopoulos, CB Verchere, J Vidal, F Wang, M Cnop, ... Diabetes 52 (2), 372-379, 2003 | 139 | 2003 |
| Impact of intra-abdominal fat and age on insulin sensitivity and β-cell function KM Utzschneider, DB Carr, RL Hull, K Kodama, JB Shofer, BM Retzlaff, ... Diabetes 53 (11), 2867-2872, 2004 | 134 | 2004 |
| Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid … RL Hull, ZP Shen, MR Watts, K Kodama, DB Carr, KM Utzschneider, ... Diabetes 54 (7), 2235-2244, 2005 | 116 | 2005 |
| Human islets have fewer blood vessels than mouse islets and the density of islet vascular structures is increased in type 2 diabetes M Brissova, A Shostak, CL Fligner, FL Revetta, MK Washington, ... Journal of Histochemistry & Cytochemistry 63 (8), 637-645, 2015 | 115 | 2015 |
| The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation PL Bollyky, M Bogdani, JB Bollyky, RL Hull, TN Wight Current diabetes reports 12, 471-480, 2012 | 107 | 2012 |
