| Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage AC Komor, YB Kim, MS Packer, JA Zuris, DR Liu Nature 533 (7603), 420-424, 2016 | 4778 | 2016 |
| Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo JA Zuris, DB Thompson, Y Shu, JP Guilinger, JL Bessen, JH Hu, ... Nature biotechnology 33 (1), 73-80, 2015 | 1504 | 2015 |
| Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles M Wang, JA Zuris, F Meng, H Rees, S Sun, P Deng, Y Han, X Gao, ... Proceedings of the National Academy of Sciences 113 (11), 2868-2873, 2016 | 601 | 2016 |
| Small molecule–triggered Cas9 protein with improved genome-editing specificity KM Davis, V Pattanayak, DB Thompson, JA Zuris, DR Liu Nature chemical biology 11 (5), 316-318, 2015 | 484 | 2015 |
| Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein JA Zuris, Y Harir, AR Conlan, M Shvartsman, D Michaeli, S Tamir, ... Proceedings of the National Academy of Sciences 108 (32), 13047-13052, 2011 | 145 | 2011 |
| Continuous directed evolution of DNA-binding proteins to improve TALEN specificity BP Hubbard, AH Badran, JA Zuris, JP Guilinger, KM Davis, L Chen, ... Nature methods 12 (10), 939-942, 2015 | 136 | 2015 |
| Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2 AR Conlan, HL Axelrod, AE Cohen, EC Abresch, J Zuris, D Yee, ... Journal of molecular biology 392 (1), 143-153, 2009 | 135 | 2009 |
| Use of cationic lipids to deliver CAS9 DR Liu, JA Zuris, DB Thompson US Patent 9,737,604, 2017 | 128 | 2017 |
| Delivery system for functional nucleases DR Liu, JA Zuris, DB Thompson US Patent 9,526,784, 2016 | 123 | 2016 |
| Characterization of Arabidopsis NEET Reveals an Ancient Role for NEET Proteins in Iron Metabolism R Nechushtai, AR Conlan, Y Harir, L Song, O Yogev, ... The Plant Cell 24 (5), 2139-2154, 2012 | 102 | 2012 |
| Redox characterization of the FeS protein MitoNEET and impact of thiazolidinedione drug binding DW Bak, JA Zuris, ML Paddock, PA Jennings, SJ Elliott Biochemistry 48 (43), 10193-10195, 2009 | 89 | 2009 |
| AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines L Zhang, JA Zuris, R Viswanathan, JN Edelstein, R Turk, B Thommandru, ... Nature communications 12 (1), 3908, 2021 | 82 | 2021 |
| Delivery system for functional nucleases DR Liu, JA Zuris, DB Thompson US Patent 10,682,410, 2020 | 73 | 2020 |
| Delivery of negatively charged proteins using cationic lipids DR Liu, DB Thompson, JA Zuris US Patent 9,999,671, 2018 | 69 | 2018 |
| Engineering the redox potential over a wide range within a new class of FeS proteins JA Zuris, DA Halim, AR Conlan, EC Abresch, R Nechushtai, ML Paddock, ... Journal of the American Chemical Society 132 (38), 13120-13122, 2010 | 67 | 2010 |
| Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1 S Tamir, S Rotem-Bamberger, C Katz, F Morcos, KL Hailey, JA Zuris, ... Proceedings of the National Academy of Sciences 111 (14), 5177-5182, 2014 | 59 | 2014 |
| Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs S Tamir, JA Zuris, L Agranat, CH Lipper, AR Conlan, D Michaeli, Y Harir, ... PLoS One 8 (5), e61202, 2013 | 55 | 2013 |
| NADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an apo-acceptor protein JA Zuris, SS Ali, H Yeh, TA Nguyen, R Nechushtai, ML Paddock, ... Journal of Biological Chemistry 287 (15), 11649-11655, 2012 | 45 | 2012 |
| Delivery of negatively charged proteins using cationic lipids DR Liu, DB Thompson, JA Zuris US Patent 10,912,833, 2021 | 41 | 2021 |
| Detection and modulation of DNA translocations during multi-gene genome editing in T cells A Bothmer, KW Gareau, HS Abdulkerim, F Buquicchio, L Cohen, ... The CRISPR journal 3 (3), 177-187, 2020 | 39 | 2020 |
Brent DorrInvestigator at GlaxoSmithKline R&D, Synthetic BiochemistryVerified email at gsk.com
