New insights into the molecular and cellular functions of poly (ADP-ribose) and PARPs BA Gibson, WL Kraus Nature reviews Molecular cell biology 13 (7), 411-424, 2012 | 1273 | 2012 |
Organization of chromatin by intrinsic and regulated phase separation BA Gibson, LK Doolittle, MWG Schneider, LE Jensen, N Gamarra, ... Cell 179 (2), 470-484. e21, 2019 | 801 | 2019 |
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA J Liu, T Doty, B Gibson, WD Heyer Nature structural & molecular biology 17 (10), 1260-1262, 2010 | 502 | 2010 |
Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation BA Gibson, Y Zhang, H Jiang, KM Hussey, JH Shrimp, H Lin, F Schwede, ... Science 353 (6294), 45-50, 2016 | 332 | 2016 |
PARP-1 controls the adipogenic transcriptional program by PARylating C/EBPβ and modulating its transcriptional activity X Luo, KW Ryu, DS Kim, T Nandu, CJ Medina, R Gupte, BA Gibson, ... Molecular cell 65 (2), 260-271, 2017 | 103 | 2017 |
Generation and characterization of recombinant antibody-like ADP-ribose binding proteins BA Gibson, LB Conrad, D Huang, WL Kraus Biochemistry 56 (48), 6305-6316, 2017 | 99 | 2017 |
A mitotic chromatin phase transition prevents perforation by microtubules MWG Schneider, BA Gibson, S Otsuka, MFD Spicer, M Petrovic, ... Nature 609 (7925), 183-190, 2022 | 45 | 2022 |
Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells LH Palavalli Parsons, S Challa, BA Gibson, T Nandu, MKS Stokes, ... Elife 10, e60481, 2021 | 42 | 2021 |
Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin I Strohkendl, FA Saifuddin, BA Gibson, MK Rosen, R Russell, ... Science advances 7 (11), eabd6030, 2021 | 33 | 2021 |
ADP-ribosylation levels and patterns correlate with gene expression and clinical outcomes in ovarian cancers LB Conrad, KY Lin, T Nandu, BA Gibson, JS Lea, WL Kraus Molecular cancer therapeutics 19 (1), 282-291, 2020 | 24 | 2020 |
In diverse conditions, intrinsic chromatin condensates have liquid-like material properties BA Gibson, C Blaukopf, T Lou, L Chen, LK Doolittle, I Finkelstein, ... Proceedings of the National Academy of Sciences 120 (18), e2218085120, 2023 | 23 | 2023 |
Organization and regulation of chromatin by liquid-liquid phase separation BA Gibson, LK Doolittle, LE Jensen, N Gamarra, S Redding, MK Rosen BioRxiv, 523662, 2019 | 23 | 2019 |
Identification of Protein Substrates of Specific PARP Enzymes Using Analog-Sensitive PARP Mutants and a “Clickable” NAD+ Analog BA Gibson, WL Kraus Poly (ADP-Ribose) Polymerase: Methods and Protocols, 111-135, 2017 | 17 | 2017 |
Small molecules, big effects: a role for chromatin-localized metabolite biosynthesis in gene regulation BA Gibson, WL Kraus Molecular cell 41 (5), 497-499, 2011 | 14 | 2011 |
ADP-ribose detection reagents WL KRAUS, BA Gibson US Patent 9,599,606, 2017 | 12 | 2017 |
A chromatin phase transition protects mitotic chromosomes against microtubule perforation MWG Schneider, BA Gibson, S Otsuka, MFD Spicer, M Petrovic, ... bioRxiv, 2021.07. 05.450834, 2021 | 5 | 2021 |
Identifying genomic sites of adp-ribosylation mediated by specific nuclear parp enzymes using Click-ChIP RA Rogge, BA Gibson, WL Kraus ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 371-387, 2018 | 3 | 2018 |
NAD analogs and methods of using said NAD analogs in determining ribosylation of proteins with PARP mutants WL KRAUS, BA Gibson, F Schwede, H Lin US Patent 9,926,340, 2018 | 2 | 2018 |
Chemical Genetic and Genomic Discovery of PARP-1-Dependent Mechansims of Transcriptional Regulation BA Gibson | | 2016 |