| A mammalian microRNA expression atlas based on small RNA library sequencing P Landgraf, M Rusu, R Sheridan, A Sewer, N Iovino, A Aravin, S Pfeffer, ... Cell 129 (7), 1401-1414, 2007 | 4539 | 2007 |
| NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ... Nature 464 (7293), 1357-1361, 2010 | 4185 | 2010 |
| Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization V Hornung, F Bauernfeind, A Halle, EO Samstad, H Kono, KL Rock, ... Nature immunology 9 (8), 847-856, 2008 | 3473 | 2008 |
| 5'-Triphosphate RNA is the ligand for RIG-I V Hornung, J Ellegast, S Kim, K Brzózka, A Jung, H Kato, H Poeck, ... science 314 (5801), 994-997, 2006 | 3166 | 2006 |
| Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ... The Journal of Immunology 183 (2), 787-791, 2009 | 3135 | 2009 |
| AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC V Hornung, A Ablasser, M Charrel-Dennis, F Bauernfeind, G Horvath, ... Nature 458 (7237), 514-518, 2009 | 2930 | 2009 |
| The NALP3 inflammasome is involved in the innate immune response to amyloid-β A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ... Nature immunology 9 (8), 857-865, 2008 | 2809 | 2008 |
| Quantitative expression of toll-like receptor 1–10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides V Hornung, S Rothenfusser, S Britsch, A Krug, B Jahrsdörfer, T Giese, ... The Journal of immunology 168 (9), 4531-4537, 2002 | 2665 | 2002 |
| Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7 V Hornung, M Guenthner-Biller, C Bourquin, A Ablasser, M Schlee, ... Nature medicine 11 (3), 263-270, 2005 | 1758 | 2005 |
| cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING A Ablasser, M Goldeck, T Cavlar, T Deimling, G Witte, I Röhl, KP Hopfner, ... Nature 498 (7454), 380-384, 2013 | 1615 | 2013 |
| The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses VAK Rathinam, Z Jiang, SN Waggoner, S Sharma, LE Cole, L Waggoner, ... Nature immunology 11 (5), 395-402, 2010 | 1537 | 2010 |
| Molecular mechanisms and cellular functions of cGAS–STING signalling KP Hopfner, V Hornung Nature reviews Molecular cell biology 21 (9), 501-521, 2020 | 1261 | 2020 |
| Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells A Krug, S Rothenfusser, V Hornung, B Jahrsdörfer, S Blackwell, ZK Ballas, ... European journal of immunology 31 (7), 2154-2163, 2001 | 1198 | 2001 |
| RIG-I-dependent sensing of poly (dA: dT) through the induction of an RNA polymerase III–transcribed RNA intermediate A Ablasser, F Bauernfeind, G Hartmann, E Latz, KA Fitzgerald, V Hornung Nature immunology 10 (10), 1065-1072, 2009 | 1113 | 2009 |
| Toll‐like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL‐12 A Krug, A Towarowski, S Britsch, S Rothenfusser, V Hornung, R Bals, ... European journal of immunology 31 (10), 3026-3037, 2001 | 1074 | 2001 |
| Recognition of 5′ triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus M Schlee, A Roth, V Hornung, CA Hagmann, V Wimmenauer, W Barchet, ... Immunity 31 (1), 25-34, 2009 | 970 | 2009 |
| Structural mechanism of cytosolic DNA sensing by cGAS F Civril, T Deimling, CC de Oliveira Mann, A Ablasser, M Moldt, G Witte, ... Nature 498 (7454), 332-337, 2013 | 830 | 2013 |
| Human monocytes engage an alternative inflammasome pathway MM Gaidt, TS Ebert, D Chauhan, T Schmidt, JL Schmid-Burgk, F Rapino, ... Immunity 44 (4), 833-846, 2016 | 826 | 2016 |
| Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome F Bauernfeind, E Bartok, A Rieger, L Franchi, G Núñez, V Hornung The Journal of Immunology 187 (2), 613-617, 2011 | 710 | 2011 |
| Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP A Ablasser, JL Schmid-Burgk, I Hemmerling, GL Horvath, T Schmidt, ... Nature 503 (7477), 530-534, 2013 | 678 | 2013 |
Katherine FitzgeraldProfessor of Medicine, University of Massachusetts Medical SchoolVerified email at umassmed.edu
