Katherine Fitzgerald
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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ...
Nature 464 (7293), 1357-1361, 2010
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
V Hornung, F Bauernfeind, A Halle, EO Samstad, H Kono, KL Rock, ...
Nature immunology 9 (8), 847-856, 2008
IKKε and TBK1 are essential components of the IRF3 signaling pathway
KA Fitzgerald, SM McWhirter, KL Faia, DC Rowe, E Latz, DT Golenbock, ...
Nature immunology 4 (5), 491-496, 2003
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ...
The Journal of Immunology 183 (2), 787-791, 2009
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
K Nakahira, JA Haspel, VAK Rathinam, SJ Lee, T Dolinay, HC Lam, ...
Nature immunology 12 (3), 222-230, 2011
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
V Hornung, A Ablasser, M Charrel-Dennis, F Bauernfeind, G Horvath, ...
Nature 458 (7237), 514-518, 2009
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ...
Nature immunology 9 (8), 857-865, 2008
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
K Shimada, TR Crother, J Karlin, J Dagvadorj, N Chiba, S Chen, ...
Immunity 36 (3), 401-414, 2012
IFI16 is an innate immune sensor for intracellular DNA
L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ...
Nature immunology 11 (11), 997-1004, 2010
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
E Latz, A Schoenemeyer, A Visintin, KA Fitzgerald, BG Monks, CF Knetter, ...
Nature immunology 5 (2), 190-198, 2004
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
KA Fitzgerald, EM Palsson-McDermott, AG Bowie, CA Jefferies, ...
Nature 413 (6851), 78-83, 2001
Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
J Tian, AM Avalos, SY Mao, B Chen, K Senthil, H Wu, P Parroche, ...
Nature immunology 8 (5), 487-496, 2007
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors
SR Woo, MB Fuertes, L Corrales, S Spranger, MJ Furdyna, MYK Leung, ...
Immunity 41 (5), 830-842, 2014
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the toll adapters TRAM and TRIF
KA Fitzgerald, DC Rowe, BJ Barnes, DR Caffrey, A Visintin, E Latz, ...
The Journal of experimental medicine 198 (7), 1043-1055, 2003
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
VAK Rathinam, Z Jiang, SN Waggoner, S Sharma, LE Cole, L Waggoner, ...
Nature immunology 11 (5), 395-402, 2010
Toll-like receptors and the control of immunity
KA Fitzgerald, JC Kagan
Cell 180 (6), 1044-1066, 2020
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
CS Shi, K Shenderov, NN Huang, J Kabat, M Abu-Asab, KA Fitzgerald, ...
Nature immunology 13 (3), 255-263, 2012
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
A Lu, VG Magupalli, J Ruan, Q Yin, MK Atianand, MR Vos, GF Schröder, ...
Cell 156 (6), 1193-1206, 2014
RIG-I-dependent sensing of poly (dA: dT) through the induction of an RNA polymerase III–transcribed RNA intermediate
A Ablasser, F Bauernfeind, G Hartmann, E Latz, KA Fitzgerald, V Hornung
Nature immunology 10 (10), 1065-1072, 2009
Regulation of inflammasome signaling
VAK Rathinam, SK Vanaja, KA Fitzgerald
Nature immunology 13 (4), 333-342, 2012
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