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Ryan A McClure
Ryan A McClure
Senior Scientist at AbbVie Inc
Verified email at abbvie.com
Title
Cited by
Cited by
Year
Metabologenomics: correlation of microbial gene clusters with metabolites drives discovery of a nonribosomal peptide with an unusual amino acid monomer
AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ...
ACS central science 2 (2), 99-108, 2016
1262016
In Vitro Reconstruction of Nonribosomal Peptide Biosynthesis Directly from DNA Using Cell-Free Protein Synthesis
AW Goering, J Li, RA McClure, RJ Thomson, MC Jewett, NL Kelleher
ACS synthetic biology 6 (1), 39-44, 2017
962017
Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation
JC Albright, MT Henke, AA Soukup, RA McClure, RJ Thomson, NP Keller, ...
ACS chemical biology 10 (6), 1535-1541, 2015
932015
Natural products from thioester reductase containing biosynthetic pathways
MW Mullowney, RA McClure, MT Robey, NL Kelleher, RJ Thomson
Natural product reports 35 (9), 847-878, 2018
652018
New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans
MT Henke, AA Soukup, AW Goering, RA McClure, RJ Thomson, NP Keller, ...
ACS chemical biology 11 (8), 2117-2123, 2016
552016
Elucidating the rimosamide-detoxin natural product families and their biosynthesis using metabolite/gene cluster correlations
RA McClure, AW Goering, KS Ju, JA Baccile, FC Schroeder, WW Metcalf, ...
ACS chemical biology 11 (12), 3452-3460, 2016
482016
Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics
EI Parkinson, JH Tryon, AW Goering, KS Ju, RA McClure, JD Kemball, ...
ACS chemical biology 13 (4), 1029-1037, 2018
432018
Gobichelin A and B: mixed-ligand siderophores discovered using proteomics
Y Chen, M Unger, I Ntai, RA McClure, JC Albright, RJ Thomson, ...
Medchemcomm 4 (1), 233-238, 2013
422013
Proteomics guided discovery of flavopeptins: Anti-proliferative aldehydes synthesized by a reductase domain-containing non-ribosomal peptide synthetase
Y Chen, RA McClure, Y Zheng, RJ Thomson, NL Kelleher
Journal of the American Chemical Society 135 (28), 10449-10456, 2013
402013
Impact of mass spectrometry-based technologies and strategies on chemoproteomics as a tool for drug discovery
RA McClure, JD Williams
ACS medicinal chemistry letters 9 (8), 785-791, 2018
212018
The HPK1 inhibitor A-745 verifies the potential of modulating T cell kinase signaling for immunotherapy
S Malchow, A Korepanova, SC Panchal, RA McClure, KL Longenecker, ...
ACS Chemical Biology 17 (3), 556-566, 2022
192022
Screening for expressed nonribosomal peptide synthetases and polyketide synthases using LC-MS/MS-based proteomics
Y Chen, RA McClure, NL Kelleher
Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols, 135-147, 2016
62016
Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer. ACS Cent Sci. 2016; 2 …
AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ...
5
Targeting IRAK3 for degradation to enhance IL-12 pro-inflammatory cytokine production
A Rowley, BS Brown, M Stofega, H Hoh, R Mathew, V Marin, RX Ding, ...
ACS Chemical Biology 17 (6), 1315-1320, 2022
42022
Inhibition of MALT1 and BCL2 induces synergistic anti-tumor activity in models of B cell lymphoma
JP Plotnik, AE Richardson, H Yang, E Rojas, V Bontcheva, C Dowell, ...
Molecular Cancer Therapeutics, 2024
2024
MALT1 protease inhibition overcomes BTK inhibitor resistance and shows synergistic activity with venetoclax in models of B cell lymphoma and leukemia
J Plotnik, V Bontcheva, C Dowell, C Will, J Chen, A Richardson, ...
Blood 142, 5009, 2023
2023
Front Cover: A Dual‐Purpose Bromocoumarin Tag Enables Deep Profiling of the Cellular Cysteinome
AJ Rabalski, JD Williams, RA McClure, A Vasudevan, A Baranczak
PROTEOMICS 19 (11), 1970091, 2019
2019
A Dual‐Purpose Bromocoumarin Tag Enables Deep Profiling of the Cellular Cysteinome
AJ Rabalski, JD Williams, RA McClure, A Vasudevan, A Baranczak
Proteomics 19 (11), 1800433, 2019
2019
Exploring Microbial Secondary Metabolism through Omics Technologies and Chemical Synthesis
RA McClure
Northwestern University, 2016
2016
Omics-based discovery of the rimosamides: A new class of nonribosomal peptide-polyketide hybrids
R McClure, J Doroghazi, A Goering, Y Chen, W Metcalf, R Thomson, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015
2015
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