Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis … PK Gupta, A Chullikana, M Rengasamy, N Shetty, V Pandey, V Agarwal, ... Arthritis research & therapy 18, 1-18, 2016 | 281 | 2016 |
Are serum-free and xeno-free culture conditions ideal for large scale clinical grade expansion of Wharton’s jelly derived mesenchymal stem cells? A comparative study P Swamynathan, P Venugopal, S Kannan, C Thej, U Kolkundar, ... Stem cell research & therapy 5, 1-17, 2014 | 131 | 2014 |
Administration of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells in critical limb ischemia due to Buerger's disease: phase II study … PK Gupta, M Krishna, A Chullikana, S Desai, R Murugesan, S Dutta, ... Stem cells translational medicine 6 (3), 689-699, 2017 | 83 | 2017 |
Higher propensity of Wharton's jelly derived mesenchymal stromal cells towards neuronal lineage in comparison to those derived from adipose and bone marrow S Balasubramanian, C Thej, P Venugopal, N Priya, Z Zakaria, ... Cell Biology International 37 (5), 507-515, 2013 | 80 | 2013 |
Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells M Rengasamy, G Singh, NA Fakharuzi, Siddikuzzaman, ... Stem cell research & therapy 8, 1-12, 2017 | 42 | 2017 |
Development of a surrogate potency assay to determine the angiogenic activity of Stempeucel®, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell … C Thej, B Ramadasse, A Walvekar, AS Majumdar, S Balasubramanian Stem cell research & therapy 8, 1-14, 2017 | 34 | 2017 |
Evaluation of the secretome profile and functional characteristics of human bone marrow mesenchymal stromal cells-derived conditioned medium suggest potential for skin rejuvenation S Balasubramanian, C Thej, A Walvekar, P Swamynathan, PK Gupta, ... Journal of Cosmetics, Dermatological Sciences and Applications 7 (01), 99, 2017 | 18 | 2017 |
Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition G Huang, Z Cheng, A Hildebrand, C Wang, M Cimini, R Roy, ... Theranostics 12 (9), 4415, 2022 | 14 | 2022 |
Phase IV postmarketing surveillance study shows continued efficacy and safety of Stempeucel in patients with critical limb ischemia due to Buerger's disease PK Gupta, S Dutta, S Kala, M Nekkanti, SC Desai, SS Mahapatra, A Dhar, ... Stem cells translational medicine 10 (12), 1602-1613, 2021 | 13 | 2021 |
Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and … C Thej, S Balasubramanian, M Rengasamy, A Walvekar, P Swamynathan, ... Stem Cell Research & Therapy 12 (1), 279, 2021 | 12 | 2021 |
Methods of upscaling mesenchymal stromal cell production, compositions and kit thereof U Kokundkar, SS Raj, S Balasubramanian, C Thej, AK Mruthynjaya, ... US Patent App. 14/597,135, 2016 | 12 | 2016 |
Unfathomed nanomessages to the heart: translational implications of stem cell-derived, progenitor cell exosomes in cardiac repair and regeneration C Thej, R Kishore Cells 10 (7), 1811, 2021 | 8 | 2021 |
Regenerative Medicine: Laboratory to Clinic A Mukhopadhyay Springer Singapore, 2017 | 8 | 2017 |
Mesenchymal stromal cells for the treatment of osteoarthritis of knee joint: context and perspective PK Gupta, C Thej Annals of Translational Medicine 7 (Suppl 6), 2019 | 4 | 2019 |
Stromal dells derived conditioned medium, method of obtaining said conditioned medium compositions, formulations and applications thereof S Balasubramanian, SS Raj, C Thej, RR BHONDE, RN SEETHARAM, ... US Patent App. 14/912,306, 2016 | 3 | 2016 |
A First of its kind Phase II clinical trial in critical limb ischemia patients using bone marrow derived, pooled, allogeneic mesenchymal stromal cells (Stempeucel®) AS Majumdar, S Balasubramanian, C Thej, M Rajkumar, M Krishna, ... Cytotherapy 17 (6), S84, 2015 | 3 | 2015 |
Allogeneic mesenchymal stem cell therapy for knee osteoarthritis: safety and efficacy results of a randomized, double blind, phase 2, placebo controlled, dose finding study A Majumdar, S Balasubramanian, C Thej, M Zagan, S SundarRaj, ... Cytotherapy 16 (4), S105, 2014 | 3 | 2014 |
A Phase II Dose Escalation Study of Intraarterial (Hepatic) Adult Human Bone Marrow Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells (Stempeucel®) in Patients … PK Gupta, A Chullikana, RN Seetharam, U Kolkundar, P Shivashankar, ... | 2 | 2021 |
Management of ischemia using pooled mesenchymal stromal cell composition AS Majumdar, PK Gupta, AC HOUSE, S Balasubramanian, C Thej, ... US Patent 10,471,101, 2019 | 2 | 2019 |
The Role of Mesenchymal Stromal Cells in the Management of Osteoarthritis of the Knee C Thej, PK Gupta Update on Mesenchymal and Induced Pluripotent Stem Cells, 2019 | 2 | 2019 |