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Christopher Wardell
Christopher Wardell
Assistant Professor of Bioinformatics, University of Arkansas for Medical Sciences
Verifierad e-postadress på uams.edu
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Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer
A Fujimoto, M Furuta, Y Totoki, T Tsunoda, M Kato, Y Shiraishi, H Tanaka, ...
Nature genetics 48 (5), 500-509, 2016
6892016
Mutational spectrum, copy number changes, and outcome: results of a sequencing study of patients with newly diagnosed myeloma
BA Walker, EM Boyle, CP Wardell, A Murison, DB Begum, NM Dahir, ...
Journal of clinical oncology 33 (33), 3911-3920, 2015
6212015
A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial
KD Boyd, FM Ross, L Chiecchio, GP Dagrada, ZJ Konn, WJ Tapper, ...
Leukemia 26 (2), 349-355, 2012
4112012
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, FE Davies, ...
Blood, The Journal of the American Society of Hematology 132 (6), 587-597, 2018
4082018
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, F Davies, ...
Leukemia 33 (1), 159-170, 2019
4072019
Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
L Rasche, SS Chavan, OW Stephens, PH Patel, R Tytarenko, C Ashby, ...
Nature communications 8 (1), 268, 2017
3522017
Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms
BA Walker, CP Wardell, L Melchor, A Brioli, DC Johnson, MF Kaiser, ...
Leukemia 28 (2), 384-390, 2014
3442014
APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma
BA Walker, CP Wardell, A Murison, EM Boyle, DB Begum, NM Dahir, ...
Nature communications 6 (1), 6997, 2015
3332015
Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t (4; 14) and t (11; 14) myeloma
BA Walker, CP Wardell, L Melchor, S Hulkki, NE Potter, DC Johnson, ...
Blood, The Journal of the American Society of Hematology 120 (5), 1077-1086, 2012
3122012
Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma
BA Walker, CP Wardell, L Chiecchio, EM Smith, KD Boyd, A Neri, ...
Blood, The Journal of the American Society of Hematology 117 (2), 553-562, 2011
3112011
Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations
CP Wardell, M Fujita, T Yamada, M Simbolo, M Fassan, R Karlic, P Polak, ...
Journal of hepatology 68 (5), 959-969, 2018
3102018
Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma
L Melchor, A Brioli, CP Wardell, A Murison, NE Potter, MF Kaiser, ...
Leukemia 28 (8), 1705-1715, 2014
2882014
Mapping of Chromosome 1p Deletions in Myeloma Identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as Being Genes in Regions Associated with Adverse Survival
KD Boyd, FM Ross, BA Walker, CP Wardell, WJ Tapper, L Chiecchio, ...
Clinical cancer research 17 (24), 7776-7784, 2011
2272011
Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients
BA Walker, CP Wardell, A Brioli, E Boyle, MF Kaiser, DB Begum, NB Dahir, ...
Blood cancer journal 4 (3), e191-e191, 2014
2112014
Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells
BA Walker, CP Wardell, DC Johnson, MF Kaiser, DB Begum, NB Dahir, ...
Blood, The Journal of the American Society of Hematology 121 (17), 3413-3419, 2013
2032013
Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma
MF Kaiser, DC Johnson, P Wu, BA Walker, A Brioli, F Mirabella, ...
Blood, The Journal of the American Society of Hematology 122 (2), 219-226, 2013
1952013
Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma
L Rasche, D Alapat, M Kumar, G Gershner, J McDonald, CP Wardell, ...
Leukemia 33 (7), 1713-1722, 2019
1362019
The clinical impact and molecular biology of del (17p) in multiple myeloma treated with conventional or thalidomide‐based therapy
KD Boyd, FM Ross, WJ Tapper, L Chiecchio, GP Dagrada, ZJ Konn, ...
Genes, chromosomes and cancer 50 (10), 765-774, 2011
1132011
The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma
A Mikulasova, CP Wardell, A Murison, EM Boyle, GH Jackson, J Smetana, ...
Haematologica 102 (9), 1617, 2017
1052017
Cancer whole-genome sequencing: present and future
H Nakagawa, CP Wardell, M Furuta, H Taniguchi, A Fujimoto
Oncogene 34 (49), 5943-5950, 2015
1052015
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Artiklar 1–20