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Michael R Barnes
Michael R Barnes
Professor of Bioinformatics, Centre for Translational Bioinformatics, QMUL
Verifierad e-postadress på qmul.ac.uk - Startsida
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Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity
LK Hosking, PR Boyd, CF Xu, M Nissum, K Cantone, IJ Purvis, R Khakhar, ...
The Pharmacogenomics Journal 2 (3), 165-175, 2002
49272002
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
SH Lee, S Ripke, BM Neale, SV Faraone, SM Purcell, RH Perlis, ...
Nature genetics 45 (9), 984-994, 2013
23172013
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
BE Johnson, T Mazor, C Hong, M Barnes, K Aihara, CY McLean, ...
Science 343 (6167), 189-193, 2014
14082014
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ...
Nature genetics 50 (10), 1412-1425, 2018
11222018
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
H Li, S Wetten, L Li, PLS Jean, R Upmanyu, L Surh, D Hosford, ...
Archives of neurology 65 (1), 45-53, 2008
5902008
Disruption of the neurexin 1 gene is associated with schizophrenia
D Rujescu, A Ingason, S Cichon, OPH Pietiläinen, MR Barnes, ...
Human molecular genetics 18 (5), 988-996, 2009
5782009
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, ...
Nature genetics 49 (3), 403-415, 2017
5692017
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ...
Nature neuroscience 18 (2), 199-209, 2015
5172015
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
SE Baranzini, NW Galwey, J Wang, P Khankhanian, R Lindberg, ...
Human molecular genetics 18 (11), 2078-2090, 2009
4702009
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
GB Ehret, T Ferreira, DI Chasman, AU Jackson, EM Schmidt, T Johnson, ...
Nature genetics 48 (10), 1171-1184, 2016
4272016
Use of genome-wide association studies for drug repositioning
P Sanseau, P Agarwal, MR Barnes, T Pastinen, JB Richards, LR Cardon, ...
Nature biotechnology 30 (4), 317-320, 2012
4132012
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
Molecular psychiatry 18 (4), 2013
3902013
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
R Uher, N Perroud, MYM Ng, J Hauser, N Henigsberg, W Maier, O Mors, ...
American Journal of Psychiatry 167 (5), 555-564, 2010
3852010
Clinical applications of machine learning algorithms: beyond the black box
DS Watson, J Krutzinna, IN Bruce, CEM Griffiths, IB McInnes, MR Barnes, ...
Bmj 364, 2019
3482019
Health and population effects of rare gene knockouts in adult humans with related parents
VM Narasimhan, KA Hunt, D Mason, CL Baker, KJ Karczewski, ...
Science 352 (6284), 474-477, 2016
3142016
Genome-wide association study of major recurrent depression in the UK population
CM Lewis, MY Ng, AW Butler, S Cohen-Woods, R Uher, K Pirlo, ...
American Journal of Psychiatry 167 (8), 949-957, 2010
2902010
Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization
D Brömme, Z Li, M Barnes, E Mehler
Biochemistry 38 (8), 2377-2385, 1999
2781999
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins
I Postmus, S Trompet, HA Deshmukh, MR Barnes, X Li, HR Warren, ...
Nature communications 5 (1), 5068, 2014
2772014
Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome
HR Wong, TP Shanley, B Sakthivel, N Cvijanovich, R Lin, GL Allen, ...
Physiological genomics 30 (2), 146-155, 2007
2752007
Molecular portraits of early rheumatoid arthritis identify clinical and treatment response phenotypes
MJ Lewis, MR Barnes, K Blighe, K Goldmann, S Rana, JA Hackney, ...
Cell reports 28 (9), 2455-2470. e5, 2019
2712019
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Artiklar 1–20