Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic S Maher, TW Leonard, J Jacobsen, DJ Brayden Advanced drug delivery reviews 61 (15), 1427-1449, 2009 | 265 | 2009 |
Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies K Kleberg, J Jacobsen, A Müllertz Journal of Pharmacy and Pharmacology 62 (11), 1656-1668, 2010 | 151 | 2010 |
Development and in vitro/in vivo testing of mucoadhesive buccal patches releasing benzydamine and lidocaine S Burgalassi, L Panichi, MF Saettone, J Jacobsen, MR Rassing International journal of pharmaceutics 133 (1-2), 1-7, 1996 | 139 | 1996 |
TR146 cells grown on filters as a model for human buccal epithelium: I. Morphology, growth, barrier properties, and permeability J Jacobsen, B van Deurs, M Pedersen, MR Rassing International journal of pharmaceutics 125 (2), 165-184, 1995 | 119 | 1995 |
Medicated chewing gum: Pros and Cons J Jacobsen, LL Christrup, NH Jensen American journal of drug delivery 2, 75-88, 2004 | 101 | 2004 |
Filter‐grown TR146 cells as an in vitro model of human buccal epithelial permeability J Jacobsen, EB Nielsen, K Brøndum‐Nielsen, ME Christensen, HBD Olin, ... European journal of oral sciences 107 (2), 138-146, 1999 | 93 | 1999 |
Buccal iontophoretic delivery of atenolol· HCl employing a new in vitro three-chamber permeation cell J Jacobsen Journal of controlled release 70 (1-2), 83-95, 2001 | 85 | 2001 |
Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS PC Christophersen, ML Christiansen, R Holm, J Kristensen, J Jacobsen, ... European journal of pharmaceutical sciences 57, 232-239, 2014 | 82 | 2014 |
Polymeric microcontainers improve oral bioavailability of furosemide LH Nielsen, A Melero, SS Keller, J Jacobsen, T Garrigues, T Rades, ... International journal of pharmaceutics 504 (1-2), 98-109, 2016 | 80 | 2016 |
Multivariate toxicity screening of liposomal formulations on a human buccal cell line G Smistad, J Jacobsen, SA Sande International journal of pharmaceutics 330 (1-2), 14-22, 2007 | 79 | 2007 |
Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80 ML Lind, J Jacobsen, R Holm, A Müllertz European journal of pharmaceutical sciences 35 (3), 211-218, 2008 | 78 | 2008 |
Fabrication of mucoadhesive buccal films for local administration of ketoprofen and lidocaine hydrochloride by combining fused deposition modeling and inkjet printing GK Eleftheriadis, PK Monou, N Bouropoulos, J Boetker, J Rantanen, ... Journal of Pharmaceutical Sciences 109 (9), 2757-2766, 2020 | 77 | 2020 |
The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition SH Welling, F Hubálek, J Jacobsen, DJ Brayden, UL Rahbek, ST Buckley European journal of pharmaceutics and biopharmaceutics 86 (3), 544-551, 2014 | 77 | 2014 |
Cyclodextrin inclusion complexes of antimycotics intended to act in the oral cavity–drug supersaturation, toxicity on TR146 cells and release from a delivery system J Jacobsen, S Bjerregaard, M Pedersen European journal of pharmaceutics and biopharmaceutics 48 (3), 217-224, 1999 | 73 | 1999 |
Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and … ML Lind, J Jacobsen, R Holm, A Müllertz European journal of pharmaceutical sciences 32 (4-5), 261-270, 2007 | 68 | 2007 |
In vivo human buccal permeability of nicotine CL Adrian, HBD Olin, K Dalhoff, J Jacobsen International journal of pharmaceutics 311 (1-2), 196-202, 2006 | 63 | 2006 |
A mechanistic based approach for enhancing buccal mucoadhesion of chitosan E Meng-Lund, C Muff-Westergaard, C Sander, P Madelung, J Jacobsen International journal of pharmaceutics 461 (1-2), 280-285, 2014 | 57 | 2014 |
Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement C Sander, HM Nielsen, J Jacobsen International journal of pharmaceutics 458 (2), 254-261, 2013 | 55 | 2013 |
Development of an ex vivo retention model simulating bioadhesion in the oral cavity using human saliva and physiologically relevant irrigation media KD Madsen, C Sander, S Baldursdottir, AML Pedersen, J Jacobsen International journal of pharmaceutics 448 (2), 373-381, 2013 | 54 | 2013 |
In vitro, ex vivo and in vivo examination of buccal absorption of metoprolol with varying pH in TR146 cell culture, porcine buccal mucosa and Göttingen minipigs R Holm, E Meng-Lund, MB Andersen, ML Jespersen, JJ Karlsson, ... European Journal of Pharmaceutical Sciences 49 (2), 117-124, 2013 | 51 | 2013 |