Virtual and biomolecular screening converge on a selective agonist for GPR30 CG Bologa, CM Revankar, SM Young, BS Edwards, JB Arterburn, ... Nature chemical biology 2 (4), 207, 2006 | 947 | 2006 |
Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance EK Sully, N Malachowa, BO Elmore, SM Alexander, JK Femling, BM Gray, ... PLoS pathogens 10 (6), e1004174, 2014 | 375 | 2014 |
Drug repurposing from an academic perspective TI Oprea, JE Bauman, CG Bologa, T Buranda, A Chigaev, BS Edwards, ... Drug Discovery Today: Therapeutic Strategies 8 (3-4), 61-69, 2011 | 374 | 2011 |
Flow cytometry for high-throughput, high-content screening BS Edwards, T Oprea, ER Prossnitz, LA Sklar Current opinion in chemical biology 8 (4), 392-398, 2004 | 272 | 2004 |
Real time analysis of the affinity regulation of α4-integrin the physiologically activated receptor is intermediate in affinity between resting and Mn2+ or antibody activation A Chigaev, AM Blenc, JV Braaten, N Kumaraswamy, CL Kepley, ... Journal of Biological Chemistry 276 (52), 48670-48678, 2001 | 183 | 2001 |
Advancing biological understanding and therapeutics discovery with small-molecule probes SL Schreiber, JD Kotz, M Li, J Aubé, CP Austin, JC Reed, H Rosen, ... Cell 161 (6), 1252-1265, 2015 | 172 | 2015 |
Flow cytometry for high throughput screening LA Sklar, BS Edwards, FW Kuckuck US Patent 6,890,487, 2005 | 155 | 2005 |
High throughput flow cytometry FW Kuckuck, BS Edwards, LA Sklar Cytometry: The Journal of the International Society for Analytical Cytology …, 2001 | 144 | 2001 |
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes TA Bennett, BS Edwards, LA Sklar, S Rogelj The Journal of Immunology 164 (8), 4120-4129, 2000 | 136 | 2000 |
Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists BS Edwards, C Bologa, SM Young, KV Balakin, ER Prossnitz, ... Molecular pharmacology 68 (5), 1301-1310, 2005 | 128 | 2005 |
Low doses of interferon alpha result in more effective clinical natural killer cell activation. BS Edwards, JA Merritt, RC Fuhlbrigge, EC Borden The Journal of clinical investigation 75 (6), 1908-1913, 1985 | 128 | 1985 |
The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures GS Davidson, RM Joe, S Roy, O Meirelles, CP Allen, MR Wilson, ... Molecular biology of the cell 22 (7), 988-998, 2011 | 122 | 2011 |
Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening LA Sklar, MB Carter, BS Edwards Current opinion in pharmacology 7 (5), 527-534, 2007 | 120 | 2007 |
Flow cytometric analysis of ligand-receptor interactions and molecular assemblies LA Sklar, BS Edwards, SW Graves, JP Nolan, ER Prossnitz Annual review of biophysics and biomolecular structure 31 (1), 97-119, 2002 | 108 | 2002 |
α4β1 integrin affinity changes govern cell adhesion A Chigaev, G Zwartz, SW Graves, DC Dwyer, H Tsuji, TD Foutz, ... Journal of Biological Chemistry 278 (40), 38174-38182, 2003 | 103 | 2003 |
Lymphocyte subset analysis by flow cytometry Comparison of three different staining techniques and effects of blood storage LM Ashmore, GM Shopp, BS Edwards Journal of immunological methods 118 (2), 209-215, 1989 | 98 | 1989 |
Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay Z Surviladze, A Waller, Y Wu, E Romero, BS Edwards, A Wandinger-Ness, ... Journal of biomolecular screening 15 (1), 10-20, 2010 | 89 | 2010 |
Sample handling for kinetics and molecular assembly in flow cytometry LA Sklar, LC Seamer, FW Kuckuck III, RG Posner, ER Prossnitz, ... Advances in Optical Biophysics 3256, 144-153, 1998 | 87 | 1998 |
High-throughput screening with HyperCyt® flow cytometry to detect small molecule formylpeptide receptor ligands SM Young, C Bologa, ER Prossnitz, TI Oprea, LA Sklar, BS Edwards Journal of biomolecular screening 10 (4), 374-382, 2005 | 84 | 2005 |
Analysis of free intracellular calcium by flow cytometry: multiparameter and pharmacologic applications SW Burchiel, BS Edwards, FW Kuckuck, FT Lauer, ER Prossnitz, ... Methods 21 (3), 221-230, 2000 | 78 | 2000 |