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Krister Bamberg
Krister Bamberg
Early Portfolio Lead, CVRM IMED, AstraZeneca
Verifierad e-postadress på astrazeneca.com
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Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
SI Sayin, A Wahlström, J Felin, S Jäntti, HU Marschall, K Bamberg, ...
Cell metabolism 17 (2), 225-235, 2013
21082013
Structure of the PPARα and-γ ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family
P Cronet, JFW Petersen, R Folmer, N Blomberg, K Sjöblom, U Karlsson, ...
Structure 9 (8), 699-706, 2001
3982001
Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor α
KT Dalen, SM Ulven, K Bamberg, JA Gustafsson, HI Nebb
Journal of Biological Chemistry 278 (48), 48283-48291, 2003
2432003
On the role of liver X receptors in lipid accumulation in adipocytes
LK Juvet, SM Andresen, GU Schuster, KT Dalen, KAR Tobin, K Hollung, ...
Molecular endocrinology 17 (2), 172-182, 2003
2212003
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP
K Boulias, N Katrakili, K Bamberg, P Underhill, A Greenfield, I Talianidis
The EMBO journal 24 (14), 2624-2633, 2005
1742005
AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats
B Ljung, K Bamberg, B Dahllöf, A Kjellstedt, ND Oakes, J Östling, ...
Journal of lipid research 43 (11), 1855-1863, 2002
1582002
Rosiglitazone (BRL49653), a PPARγ-selective agonist, causes peroxisome proliferator-like liver effects in obese mice
U Edvardsson, M Bergström, M Alexandersson, K Bamberg, B Ljung, ...
Journal of Lipid Research 40 (7), 1177-1184, 1999
1561999
Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation
P Aåkerblad, U Lind, D Liberg, K Bamberg, M Sigvardsson
Molecular and cellular biology 22 (22), 8015-8025, 2002
1402002
Topological analysis of H+, K (+)-ATPase using in vitro translation
K Bamberg, G Sachs
Journal of Biological Chemistry 269 (24), 16909-16919, 1994
1241994
cDNA cloning and membrane topology of the rabbit gastric H+/K+-ATPase α-subunit
K Bamberg, F Mercier, MA Reuben, Y Kobayashi, KB Munson, G Sachs
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1131 (1 …, 1992
821992
Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH
M Bjursell, M Wedin, T Admyre, M Hermansson, G Böttcher, M Göransson, ...
PloS one 8 (5), e64721, 2013
792013
Gastric acid secretion: activation and inhibition.
G Sachs, C Prinz, D Loo, K Bamberg, M Besancon, JM Shin
The Yale journal of biology and medicine 67 (3-4), 81, 1994
771994
Gene expression analysis suggests that EBF-1 and PPARγ2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics
P Akerblad, R Månsson, A Lagergren, S Westerlund, B Basta, U Lind, ...
Physiological genomics 23 (2), 206-216, 2005
722005
Molecular tuning of farnesoid X receptor partial agonism
D Merk, S Sreeramulu, D Kudlinzki, K Saxena, V Linhard, SL Gande, ...
Nature Communications 10 (1), 2915, 2019
702019
β-Subunit assembly is essential for the correct packing and the stable membrane insertion of the H, K-ATPase α-subunit
AT Beggah, P Béguin, K Bamberg, G Sachs, K Geering
Journal of Biological Chemistry 274 (12), 8217-8223, 1999
661999
Differential regulation of cytosolic and peroxisomal bile acid amidation by PPARα activation favors the formation of unconjugated bile acids
K Solaas, BF Kase, V Pham, K Bamberg, MC Hunt, SEH Alexson
Journal of lipid research 45 (6), 1051-1060, 2004
532004
Acid secretion and the H, K ATPase of stomach.
C Prinz, M Kajimura, D Scott, H Helander, J Shin, M Besancon, ...
The Yale journal of biology and medicine 65 (6), 577, 1992
531992
Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion
K Bamberg, U Johansson, K Edman, L William-Olsson, S Myhre, ...
PLoS One 13 (2), e0193380, 2018
512018
Identification of the human ApoAV gene as a novel RORα target gene
U Lind, T Nilsson, J McPheat, PE Strömstedt, K Bamberg, C Balendran, ...
Biochemical and Biophysical Research Communications 330 (1), 233-241, 2005
502005
LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties
F Gilardi, M Giudici, N Mitro, O Maschi, U Guerrini, G Rando, A Maggi, ...
Journal of Biological Chemistry 289 (10), 6908-6920, 2014
452014
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Artiklar 1–20