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Thi Hoang Duong Nguyen
Thi Hoang Duong Nguyen
MRC-Laboratory of Molecular Biology
Verifierad e-postadress på mrc-lmb.cam.ac.uk
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The architecture of the spliceosomal U4/U6. U5 tri-snRNP
THD Nguyen, WP Galej, XC Bai, CG Savva, AJ Newman, SH Scheres, ...
Nature 523 (7558), 47-52, 2015
2442015
Cryo-EM structure of substrate-bound human telomerase holoenzyme
THD Nguyen, J Tam, RA Wu, BJ Greber, D Toso, E Nogales, K Collins
Nature 557 (7704), 190-195, 2018
2312018
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution
THD Nguyen, WP Galej, XC Bai, O C, AJ Newman, SH Scheres, K Nagai
Nature, 2016
2232016
Binding of low molecular weight inhibitors promotes large conformational changes in the dengue virus NS2B-NS3 protease: fold analysis by pseudocontact shifts
L de la Cruz, THD Nguyen, K Ozawa, J Shin, B Graham, T Huber, G Otting
Journal of the American Chemical Society 133 (47), 19205-19215, 2011
1372011
Structure of human telomerase holoenzyme with bound telomeric DNA
GE Ghanim, AJ Fountain, AMM Van Roon, R Rangan, R Das, K Collins, ...
Nature 593 (7859), 449-453, 2021
1212021
The cryo-electron microscopy structure of human transcription factor IIH
BJ Greber, THD Nguyen, J Fang, PV Afonine, PD Adams, E Nogales
Nature 549 (7672), 414-417, 2017
1072017
Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site
THD Nguyen, J Li, WP Galej, H Oshikane, AJ Newman, K Nagai
Structure 21 (6), 910-919, 2013
932013
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes.
SG 8. Hadler KS, Tanifum EA, Yip SH-C, Mitić N, Guddat LW, Jackson CJ, Gahan ...
Journal of American Chemical Society 130, 14129-14138, 2008
862008
Structural mechanism of ATP-independent transcription initiation by RNA polymerase I
Y Han, C Yan, THD Nguyen, AJ Jackobel, I Ivanov, BA Knutson, Y He
Elife 6, e27414, 2017
722017
Structural studies of the spliceosome: zooming into the heart of the machine
WP Galej, THD Nguyen, AJ Newman, K Nagai
Current opinion in structural biology 25, 57-66, 2014
662014
CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast
THD Nguyen, WP Galej, SM Fica, PC Lin, AJ Newman, K Nagai
Current opinion in structural biology 36, 48-57, 2016
642016
A bis-carbyne (ethanediylidyne) complex via the catalytic demercuration of a mercury bis (carbido) complex
AL Colebatch, RL Cordiner, AF Hill, KTHD Nguyen, R Shang, AC Willis
Organometallics 28 (15), 4394-4399, 2009
612009
Structural basis of human telomerase recruitment by TPP1-POT1
Z Sekne, GE Ghanim, AMM Van Roon, THD Nguyen
Science 375 (6585), 1173-1176, 2022
532022
Generation of pseudocontact shifts in protein NMR spectra with a genetically encoded cobalt (II)‐binding amino acid
THD Nguyen, K Ozawa, M Stanton‐Cook, R Barrow, T Huber, G Otting
Angewandte Chemie 123 (3), 718-720, 2011
452011
Telomerase structures and regulation: shedding light on the chromosome end
THD Nguyen, K Collins, E Nogales
Current opinion in structural biology 55, 185-193, 2019
192019
Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome
MD Healy, KE McNally, R Butkovič, M Chilton, K Kato, J Sacharz, ...
Cell 186 (10), 2219-2237. e29, 2023
162023
THD; Shang, R.; Willis, AC
AF Hill, AL Colebatch, RL Cordiner, RD Dewhurst, CAM McQueen, ...
Comments Inorg. Chem 31, 121-129, 2010
112010
Structural biology of human telomerase: progress and prospects
THD Nguyen
Biochemical Society Transactions 49 (5), 1927-1939, 2021
102021
Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife 6
Y Han, C Yan, THD Nguyen, AJ Jackobel, I Ivanov, BA Knutson, Y He
82017
Structural basis of telomeric nucleosome recognition by shelterin factor TRF1
H Hu, AMM van Roon, GE Ghanim, B Ahsan, AO Oluwole, SY Peak-Chew, ...
Science Advances 9 (34), eadi4148, 2023
32023
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