| Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors P Zhan, X Liu, J Zhu, Z Fang, Z Li, C Pannecouque, E De Clercq Bioorganic & medicinal chemistry 17 (16), 5775-5781, 2009 | 96 | 2009 |
| Dual functional immunostimulatory polymeric prodrug carrier with pendent indoximod for enhanced cancer immunochemotherapy Z Wan, J Sun, J Xu, P Moharil, J Chen, J Xu, J Zhu, J Li, Y Huang, P Xu, ... Acta biomaterialia 90, 300-313, 2019 | 50 | 2019 |
| Pregnane X receptor activation potentiates ritonavir hepatotoxicity AI Shehu, J Lu, P Wang, J Zhu, Y Wang, D Yang, D McMahon, W Xie, ... The Journal of clinical investigation 129 (7), 2898-2903, 2019 | 37 | 2019 |
| Metabolism of KO143, an ABCG2 inhibitor K Liu, J Zhu, Y Huang, C Li, J Lu, M Sachar, S Li, X Ma Drug metabolism and pharmacokinetics 32 (4), 193-200, 2017 | 36 | 2017 |
| Design, Synthesis, and Structure–Activity Relationships of 3, 4, 5‐Trisubstituted 4, 5‐Dihydro‐1, 2, 4‐oxadiazoles as TGR5 Agonists J Zhu, Y Ye, M Ning, A Mándi, Y Feng, Q Zou, T Kurtán, Y Leng, J Shen ChemMedChem 8 (7), 1210-1223, 2013 | 36 | 2013 |
| Intestinal sulfation is essential to protect against colitis and colonic carcinogenesis P Xu, Y Xi, J Zhu, M Zhang, Z Luka, DB Stolz, X Cai, Y Xie, M Xu, S Ren, ... Gastroenterology 161 (1), 271-286. e11, 2021 | 35 | 2021 |
| Metabolism and hepatotoxicity of pyrazinamide, an antituberculosis drug Z Hussain, J Zhu, X Ma Drug Metabolism and Disposition 49 (8), 679-682, 2021 | 33 | 2021 |
| The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria P Wang, M Sachar, J Lu, AI Shehu, J Zhu, J Chen, K Liu, KE Anderson, ... Science Advances 5 (9), eaaw6127, 2019 | 31 | 2019 |
| 4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists Q Zou, H Duan, M Ning, J Liu, Y Feng, L Zhang, J Zhu, Y Leng, J Shen European Journal of Medicinal Chemistry 82, 1-15, 2014 | 31 | 2014 |
| Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver Y Bao, P Wang, X Shao, J Zhu, J Xiao, J Shi, L Zhang, HJ Zhu, X Ma, ... Drug Metabolism and Disposition 48 (5), 326-336, 2020 | 29 | 2020 |
| Identification of novel pathways in idelalisib metabolism and bioactivation J Zhu, P Wang, AI Shehu, J Lu, H Bi, X Ma Chemical research in toxicology 31 (7), 548-555, 2018 | 24 | 2018 |
| Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis Y Bi, X Shi, J Zhu, X Guan, WG Garbacz, Y Huang, L Gao, J Yan, M Xu, ... Molecular and cellular biology 38 (7), e00654-17, 2018 | 23 | 2018 |
| Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold J Zhu, M Ning, C Guo, L Zhang, G Pan, Y Leng, J Shen European journal of medicinal chemistry 69, 55-68, 2013 | 22 | 2013 |
| Bi-allelic hydroxymethylbilane synthase inactivation defines a homogenous clinico-molecular subtype of hepatocellular carcinoma L Molina, J Zhu, E Trépo, Q Bayard, G Amaddeo, B Le Bail, L Chiche, ... Journal of hepatology 77 (4), 1038-1046, 2022 | 19 | 2022 |
| Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors LM Molina, J Zhu, Q Li, T Pradhan-Sundd, Y Krutsenko, K Sayed, ... Cell reports 36 (1), 2021 | 17 | 2021 |
| Impaired bile secretion promotes hepatobiliary injury in sickle cell disease R Vats, S Liu, J Zhu, D Mukhi, E Tutuncuoglu, N Cardenes, S Singh, ... Hepatology 72 (6), 2165-2181, 2020 | 17 | 2020 |
| Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice P Wang, X Shao, Y Bao, J Zhu, L Chen, L Zhang, X Ma, X Zhong Acta Pharmaceutica Sinica B 10 (1), 171-185, 2020 | 16 | 2020 |
| Targeting xenobiotic nuclear receptors PXR and CAR to prevent cobicistat hepatotoxicity AI Shehu, J Zhu, J Li, J Lu, D McMahon, W Xie, FJ Gonzalez, X Ma Toxicological Sciences 181 (1), 58-67, 2021 | 14 | 2021 |
| Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice Y Bao, M Phan, J Zhu, X Ma, JE Manautou, X Zhong Drug Metabolism and Disposition 50 (5), 694-703, 2022 | 12 | 2022 |
| Targeting metabotropic glutamate receptor 4 for cancer immunotherapy Z Wan, R Sun, YW Liu, S Li, J Sun, J Li, J Zhu, P Moharil, B Zhang, P Ren, ... Science Advances 7 (50), eabj4226, 2021 | 12 | 2021 |
