| Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination F Gong, LY Chiu, B Cox, F Aymard, T Clouaire, JW Leung, M Cammarata, ... Genes & development 29 (2), 197-211, 2015 | 242 | 2015 |
| Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis G Ghosal, JWC Leung, BC Nair, KW Fong, J Chen Journal of Biological Chemistry 287 (41), 34225-34233, 2012 | 121 | 2012 |
| Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress JWC Leung, G Ghosal, W Wang, X Shen, J Wang, L Li, J Chen Journal of Biological Chemistry 288 (9), 6342-6350, 2013 | 114 | 2013 |
| Modularized functions of the Fanconi anemia core complex Y Huang, JWC Leung, M Lowery, N Matsushita, Y Wang, X Shen, ... Cell reports 7 (6), 1849-1857, 2014 | 112 | 2014 |
| Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze WC Leung, H Zheng, M Huen, SL Law, H Xue Progress in Neuro-Psychopharmacology and Biological Psychiatry 27 (5), 775-779, 2003 | 110 | 2003 |
| PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis J Wang, JW Leung, Z Gong, L Feng, X Shi, J Chen Journal of Biological Chemistry 288 (5), 3174-3183, 2013 | 103 | 2013 |
| 5, 7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties MSY Huen, JWC Leung, W Ng, WS Lui, MNS Chan, JTF Wong, H Xue Biochemical pharmacology 66 (1), 125-132, 2003 | 103 | 2003 |
| FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions Y Wang, JW Leung, Y Jiang, MG Lowery, H Do, KM Vasquez, J Chen, ... Molecular cell 49 (5), 997-1009, 2013 | 101 | 2013 |
| Nucleosome acidic patch promotes RNF168-and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling JW Leung, P Agarwal, MD Canny, F Gong, AD Robison, IJ Finkelstein, ... PLoS genetics 10 (3), e1004178, 2014 | 96 | 2014 |
| Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair JWC Leung, Y Wang, KW Fong, MSY Huen, L Li, J Chen Proceedings of the National Academy of Sciences 109 (12), 4491-4496, 2012 | 93 | 2012 |
| Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1 MSY Huen, J Huang, JWC Leung, SMH Sy, KM Leung, YP Ching, ... Molecular cell 37 (6), 854-864, 2010 | 93 | 2010 |
| Ubiquitin‐Activated Interaction Traps (UBAIT s) identify E3 ligase binding partners HF O'Connor, N Lyon, JW Leung, P Agarwal, CD Swaim, KM Miller, ... EMBO reports 16 (12), 1699-1712, 2015 | 88 | 2015 |
| ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair JWC Leung, N Makharashvili, P Agarwal, LY Chiu, R Pourpre, ... Genes & development 31 (3), 260-274, 2017 | 77 | 2017 |
| Endothelial endothelin-1 over-expression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after … JWC Leung, SSM Chung, SK Chung Brain research 1266, 121-129, 2009 | 76 | 2009 |
| Naturally occurring 2′-hydroxyl-substituted flavonoids as high-affinity benzodiazepine site ligands MSY Huen, KM Hui, JWC Leung, E Sigel, R Baur, JTF Wong, H Xue Biochemical pharmacology 66 (12), 2397-2407, 2003 | 72 | 2003 |
| Sae2/CtIP prevents R-loop accumulation in eukaryotic cells N Makharashvili, S Arora, Y Yin, Q Fu, X Wen, JH Lee, CH Kao, ... Elife 7, e42733, 2018 | 63 | 2018 |
| SET nuclear oncogene associates with microcephalin/MCPH1 and regulates chromosome condensation JW Leung, A Leitch, JL Wood, C Shaw-Smith, K Metcalfe, LS Bicknell, ... Journal of Biological Chemistry 286 (24), 21393-21400, 2011 | 51 | 2011 |
| Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity JWC Leung, WT Wong, HW Koon, FM Mo, S Tam, Y Huang, ... PloS one 6 (11), e26994, 2011 | 47 | 2011 |
| Effect of Lycium barbarum Polysaccharides on the expression of endothelin-1 and its receptors in an ocular hypertension model of rat glaucoma☆ XS Mi, K Chiu, G Van, JWC Leung, ACY Lo, SK Chung, RCC Chang, ... Neural regeneration research 7 (9), 645-651, 2012 | 43 | 2012 |
| Targeted overexpression of endothelin-1 in astrocytes leads to more severe cytotoxic brain edema and higher mortality PKK Yeung, ACY Lo, JWC Leung, SSM Chung, SK Chung Journal of Cerebral Blood Flow & Metabolism 29 (12), 1891-1902, 2009 | 40 | 2009 |
