| Generating a prion with bacterially expressed recombinant prion protein F Wang, X Wang, CG Yuan, J Ma Science 327 (5969), 1132-1135, 2010 | 794 | 2010 |
| Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol J Ma, R Wollmann, S Lindquist Science 298 (5599), 1781-1785, 2002 | 620 | 2002 |
| Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol J Ma, S Lindquist Science 298 (5599), 1785-1788, 2002 | 392 | 2002 |
| Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation J Ma, S Lindquist Proceedings of the National Academy of Sciences 98 (26), 14955-14960, 2001 | 360 | 2001 |
| Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids NR Deleault, JR Piro, DJ Walsh, F Wang, J Ma, JC Geoghegan, ... Proceedings of the National Academy of Sciences 109 (22), 8546-8551, 2012 | 265 | 2012 |
| Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions NR Deleault, DJ Walsh, JR Piro, F Wang, X Wang, J Ma, JR Rees, ... Proceedings of the National Academy of Sciences 109 (28), E1938-E1946, 2012 | 207 | 2012 |
| Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress X Wang, B Thomas, R Sachdeva, L Arterburn, L Frye, PG Hatcher, ... Proceedings of the National Academy of Sciences 103 (10), 3604-3609, 2006 | 202 | 2006 |
| Skin α-synuclein aggregation seeding activity as a novel biomarker for Parkinson disease Z Wang, K Becker, V Donadio, S Siedlak, J Yuan, M Rezaee, A Incensi, ... JAMA neurology 78 (1), 30-40, 2021 | 196 | 2021 |
| Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration X Wang, K Becker, N Levine, M Zhang, AP Lieberman, DJ Moore, J Ma Acta neuropathologica communications 7, 1-14, 2019 | 166 | 2019 |
| De novo generation of a PrPSc-like conformation in living cells J Ma, S Lindquist Nature cell biology 1 (6), 358-361, 1999 | 150 | 1999 |
| Lipid interaction converts prion protein to a PrPSc-like proteinase K-resistant conformation under physiological conditions F Wang, F Yang, Y Hu, X Wang, X Wang, C Jin, J Ma Biochemistry 46 (23), 7045-7053, 2007 | 124 | 2007 |
| Nutritional benefit of olive oil: the biological effects of hydroxytyrosol and its arylating quinone adducts DG Cornwell, J Ma Journal of agricultural and food chemistry 56 (19), 8774-8786, 2008 | 101 | 2008 |
| Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies C Bargar, W Wang, SA Gunzler, A LeFevre, Z Wang, AJ Lerner, N Singh, ... Acta neuropathologica communications 9, 1-13, 2021 | 93 | 2021 |
| Parkinson’s disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration X Chen, JK Kordich, ET Williams, N Levine, A Cole-Strauss, L Marshall, ... Proceedings of the National Academy of Sciences 116 (12), 5765-5774, 2019 | 92 | 2019 |
| A Disulfide-bonded Dimer of the Golgi β-Galactoside α2, 6-Sialyltransferase Is Catalytically Inactive yet Still Retains the Ability to Bind Galactose (∗) J Ma, KJ Colley Journal of Biological Chemistry 271 (13), 7758-7766, 1996 | 92 | 1996 |
| Two naturally occurring α2, 6-sialyltransferase forms with a single amino acid change in the catalytic domain differ in their catalytic activity and proteolytic processing J Ma, R Qian, FM Rausa, KJ Colley Journal of Biological Chemistry 272 (1), 672-679, 1997 | 87 | 1997 |
| Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints EV Minikel, HT Zhao, J Le, J O’Moore, R Pitstick, S Graffam, GA Carlson, ... Nucleic acids research 48 (19), 10615-10631, 2020 | 86 | 2020 |
| Cofactor molecules induce structural transformation during infectious prion formation MB Miller, DW Wang, F Wang, GP Noble, J Ma, VL Woods, S Li, ... Structure 21 (11), 2061-2068, 2013 | 79 | 2013 |
| The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity X Wang, F Wang, L Arterburn, R Wollmann, J Ma Journal of Biological Chemistry 281 (19), 13559-13565, 2006 | 79 | 2006 |
| Role of the highly conserved middle region of prion protein (PrP) in PrP− lipid interaction F Wang, S Yin, X Wang, L Zha, MS Sy, J Ma Biochemistry 49 (37), 8169-8176, 2010 | 76 | 2010 |
