Vijay Shahani
Vijay Shahani
Application Scientist, Cyclica Inc.
Verified email at cyclicarx.com
Title
Cited by
Cited by
Year
Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein
S Fletcher, JA Drewry, VM Shahani, BDG Page, PT Gunning
Biochemistry and Cell Biology 87 (6), 825-833, 2009
1092009
Disruption of Transcriptionally Active Stat3 Dimers with Non‐phosphorylated, Salicylic Acid‐Based Small Molecules: Potent in vitro and Tumor Cell Activities
S Fletcher, J Singh, X Zhang, P Yue, BDG Page, S Sharmeen, ...
ChemBioChem 10 (12), 1959-1964, 2009
1002009
Potent targeting of the STAT3 protein in brain cancer stem cells: a promising route for treating glioblastoma
S Haftchenary, HA Luchman, AO Jouk, AJ Veloso, BDG Page, XR Cheng, ...
ACS medicinal chemistry letters 4 (11), 1102-1107, 2013
852013
Giving drugs a second chance: overcoming regulatory and financial hurdles in repurposing approved drugs as cancer therapeutics
JJ Hernandez, M Pryszlak, L Smith, C Yanchus, N Kurji, VM Shahani, ...
Frontiers in oncology 7, 273, 2017
552017
Concise access to N9-mono-, N2-mono-and N2, N9-di-substituted guanines via efficient Mitsunobu reactions
S Fletcher, VM Shahani, AJ Lough, PT Gunning
Tetrahedron 66 (25), 4621-4632, 2010
452010
Facile and efficient access to 2, 6, 9-tri-substituted purines through sequential N9, N2 Mitsunobu reactions
S Fletcher, VM Shahani, PT Gunning
Tetrahedron letters 50 (29), 4258-4261, 2009
412009
Identification of purine-scaffold small-molecule inhibitors of Stat3 activation by QSAR studies
VM Shahani, P Yue, S Haftchenary, W Zhao, JL Lukkarila, X Zhang, D Ball, ...
ACS medicinal chemistry letters 2 (1), 79-84, 2010
402010
Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein
VM Shahani, P Yue, S Fletcher, S Sharmeen, MA Sukhai, DP Luu, ...
Bioorganic & medicinal chemistry 19 (5), 1823-1838, 2011
382011
Identification of NAE inhibitors exhibiting potent activity in leukemia cells: exploring the structural determinants of NAE specificity
JL Lukkarila, SR da Silva, M Ali, VM Shahani, GW Xu, J Berman, ...
ACS medicinal chemistry letters 2 (8), 577-582, 2011
292011
Computational proteome-wide screening predicts neurotoxic drug-protein interactome for the investigational analgesic BIA 10-2474
SV Molinski, VM Shahani, SS MacKinnon, LD Morayniss, M Laforet, ...
Biochemical and biophysical research communications 483 (1), 502-508, 2017
112017
Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site
SV Molinski, VM Shahani, AS Subramanian, SS MacKinnon, G Woollard, ...
Proteins: Structure, Function, and Bioinformatics, 2018
102018
Identification of a potent salicylic acid-based inhibitor of tyrosine phosphatase PTP1B
S Haftchenary, DP Ball, I Aubry, M Landry, VM Shahani, S Fletcher, ...
MedChemComm 4 (6), 987-992, 2013
102013
A 2, 6, 9-hetero-trisubstituted purine inhibitor exhibits potent biological effects against multiple myeloma cells
VM Shahani, DP Ball, AV Ramos, Z Li, PA Spagnuolo, S Haftchenary, ...
Bioorganic & medicinal chemistry 21 (17), 5618-5628, 2013
92013
The efficacy of interactive analogical models in the instruction of bond energy curves in undergraduate chemistry
VM Shahani, J Jenkinson
Chemistry Education Research and Practice 17 (2), 417-428, 2016
52016
Electrochemical detection of the Fc-STAT3 phosphorylation and STAT3–Fc-STAT3 dimerization and inhibition
S Martic, MK Rains, S Haftchenary, VM Shahani, D Kraskouskaya, ...
Molecular BioSystems 10 (3), 576-580, 2014
32014
Cover Image, Volume 86, Issue 8
SV Molinski, VM Shahani, AS Subramanian, SS MacKinnon, G Woollard, ...
Proteins: Structure, Function, and Bioinformatics 86 (8), C1-C1, 2018
2018
An Exploration into the Molecular Recognition of Signal Transducer and Activator of Transcription 3 Protein Using Rationally Designed Small Molecule Binders
VM Shahani
2013
An Exploration into the Molecular Recognition of Signal Transducer and Activator of Transcription 3 Protein Using Rationally Designed Small Molecule Binders
VM Shahani
2013
Utilizing a pharmacophore model for the development of potent small molecule inhibitors of STAT3 function
VM Shahani, S Fletcher, P Bin Yue, DP Luu, S Sharmeen, AD Schimmer, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010
2010
Inside Cover: Disruption of Transcriptionally Active Stat3 Dimers with Non‐phosphorylated, Salicylic Acid‐Based Small Molecules: Potent in vitro and Tumor Cell Activities …
S Fletcher, J Singh, X Zhang, P Yue, BDG Page, S Sharmeen, ...
ChemBioChem 10 (12), 1906-1906, 2009
2009
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