Philip Van Damme
Philip Van Damme
Professor of Neuroscience, University of Leuven
Verifierad e-postadress på uzleuven.be
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EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)–revised report of an EFNS task force
EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis:
European journal of neurology 19 (3), 360-375, 2012
6542012
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ...
Nature neuroscience 8 (1), 85-92, 2005
5562005
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
L Van Den Bosch, P Van Damme, E Bogaert, W Robberecht
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006
4582006
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease
C d'Ydewalle, J Krishnan, DM Chiheb, P Van Damme, J Irobi, ...
Nature medicine 17 (8), 968-974, 2011
4032011
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
P Van Damme, A Van Hoecke, D Lambrechts, P Vanacker, E Bogaert, ...
The Journal of cell biology 181 (1), 37-41, 2008
3582008
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
3122016
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ...
Neuron 90 (3), 535-550, 2016
3062016
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ...
Nature medicine 18 (9), 1418-1422, 2012
2692012
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
2572017
Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study
A Shatunov, K Mok, S Newhouse, ME Weale, B Smith, C Vance, ...
The Lancet Neurology 9 (10), 986-994, 2010
2312010
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
P Van Damme, E Bogaert, M Dewil, N Hersmus, D Kiraly, W Scheveneels, ...
Proceedings of the National Academy of Sciences 104 (37), 14825-14830, 2007
2222007
Treatment-related peripheral neuropathy in multiple myeloma: the challenge continues
M Delforge, J Bladé, MA Dimopoulos, T Facon, M Kropff, H Ludwig, ...
The lancet oncology 11 (11), 1086-1095, 2010
2172010
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
2162018
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind …
JF Howard Jr, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, ...
The Lancet Neurology 16 (12), 976-986, 2017
2082017
Serum biomarker for progranulin‐associated frontotemporal lobar degeneration
K Sleegers, N Brouwers, P Van Damme, S Engelborghs, I Gijselinck, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
1962009
The C9ORF72 expansion mutation is a common cause of ALS+/− FTD in Europe and has a single founder
BN Smith, S Newhouse, A Shatunov, C Vance, S Topp, L Johnson, ...
European Journal of Human Genetics 21 (1), 102-108, 2013
1952013
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
T Philips, A Bento-Abreu, A Nonneman, W Haeck, K Staats, V Geelen, ...
Brain 136 (2), 471-482, 2013
1792013
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
MA Van Es, HJ Schelhaas, PWJ Van Vught, N Ticozzi, PM Andersen, ...
Annals of neurology 70 (6), 964-973, 2011
1772011
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
S Boeynaems, E Bogaert, E Michiels, I Gijselinck, A Sieben, A Jovičić, ...
Scientific reports 6 (1), 1-8, 2016
1752016
The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter
I Gijselinck, S Van Mossevelde, J van der Zee, A Sieben, S Engelborghs, ...
Molecular psychiatry 21 (8), 1112-1124, 2016
1682016
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