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Edward Curry
Edward Curry
Computational Biologist, GSK. Honorary Lecturer, Imperial College London
Verified email at imperial.ac.uk - Homepage
Title
Cited by
Cited by
Year
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489-494, 2015
14752015
Poised epigenetic states and acquired drug resistance in cancer
R Brown, E Curry, L Magnani, CS Wilhelm-Benartzi, J Borley
Nature Reviews Cancer 14 (11), 747-753, 2014
3152014
A mathematical-descriptor of tumor-mesoscopic-structure from computed-tomography images annotates prognostic-and molecular-phenotypes of epithelial ovarian cancer
H Lu, M Arshad, A Thornton, G Avesani, P Cunnea, ED Curry, F Kanavati, ...
Nature communications 10 (1), 764, 2019
1542019
LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression
M Mura, TG Hopkins, T Michael, N Abd-Latip, J Weir, E Aboagye, F Mauri, ...
Oncogene 34 (39), 5025-5036, 2015
1392015
Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis
K van Veldhoven, S Polidoro, L Baglietto, G Severi, C Sacerdote, ...
Clinical epigenetics 7, 1-12, 2015
1172015
Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells
N Chapman-Rothe, E Curry, C Zeller, D Liber, E Stronach, H Gabra, ...
Oncogene 32 (38), 4586-4592, 2013
962013
HNF4A and GATA6 loss reveals therapeutically actionable subtypes in pancreatic cancer
H Brunton, G Caligiuri, R Cunningham, R Upstill-Goddard, UM Bailey, ...
Cell reports 31 (6), 2020
892020
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells
E Curry, I Green, N Chapman-Rothe, E Shamsaei, S Kandil, FL Cherblanc, ...
Clinical epigenetics 7, 1-12, 2015
722015
RIP140 represses the “brown-in-white” adipocyte program including a futile cycle of triacyclglycerol breakdown and synthesis
E Kiskinis, L Chatzeli, E Curry, M Kaforou, A Frontini, S Cinti, G Montana, ...
Molecular endocrinology 28 (3), 344-356, 2014
632014
Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second-generation tyrosine kinase inhibitors
G Nteliopoulos, A Bazeos, S Claudiani, G Gerrard, E Curry, R Szydlo, ...
Haematologica 104 (12), 2400, 2019
492019
Genes predisposed to DNA hypermethylation during acquired resistance to chemotherapy are identified in ovarian tumors by bivalent chromatin domains at initial diagnosis
E Curry, C Zeller, N Masrour, DK Patten, J Gallon, CS Wilhelm-Benartzi, ...
Cancer Research 78 (6), 1383-1391, 2018
412018
Differential expression of IL-8 and IL-8 receptors in benign, borderline and malignant ovarian epithelial tumours
A Browne, R Sriraksa, T Guney, N Rama, S Van Noorden, E Curry, ...
Cytokine 64 (1), 413-421, 2013
382013
MicroRNAs as biomarkers for prostate cancer prognosis: a systematic review and a systematic reanalysis of public data
S Rana, GN Valbuena, E Curry, CL Bevan, HC Keun
British journal of cancer 126 (3), 502-513, 2022
372022
Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency
E Bell, EW Curry, W Megchelenbrink, L Jouneau, V Brochard, RA Tomaz, ...
Nature communications 11 (1), 1112, 2020
292020
Dose-finding quantitative 18F-FDG PET imaging study with the oral pan-AKT inhibitor GSK2141795 in patients with gynecologic malignancies
H Gungor, A Saleem, S Babar, R Dina, MA El-Bahrawy, E Curry, N Rama, ...
Journal of Nuclear Medicine 56 (12), 1828-1835, 2015
272015
A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 …
A Cheraghchi-Bashi, CA Parker, E Curry, JF Salazar, H Gungor, ...
Oncotarget 6 (39), 41736, 2015
262015
WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response
S Janczar, J Nautiyal, Y Xiao, E Curry, M Sun, E Zanini, AJW Paige, ...
Cell death & disease 8 (7), e2955-e2955, 2017
232017
Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation
RA Tomaz, JL Harman, D Karimlou, L Weavers, L Fritsch, T Bou-Kheir, ...
Development 144 (4), 567-579, 2017
232017
Molecular subtypes of serous borderline ovarian tumor show distinct expression patterns of benign tumor and malignant tumor-associated signatures
EWJ Curry, EA Stronach, NR Rama, YYP Wang, H Gabra, MA El-Bahrawy
Modern Pathology 27 (3), 433-442, 2014
232014
Tumor mutational landscape is a record of the pre-malignant state
K Kübler, R Karlić, NJ Haradhvala, K Ha, J Kim, M Kuzman, W Jiao, ...
BioRxiv, 517565, 2019
222019
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