Peter S. Choi
Peter S. Choi
Assistant Professor of Pathology, University of Pennsylvania
Verified email at - Homepage
Cited by
Cited by
Targeted genomic rearrangements using CRISPR/Cas technology
PS Choi, M Meyerson
Nature communications 5 (1), 1-6, 2014
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
X Zhang, PS Choi, JM Francis, M Imielinski, H Watanabe, AD Cherniack, ...
Nature genetics 48 (2), 176-182, 2016
A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events
AN Brooks, PS Choi, L de Waal, T Sharifnia, M Imielinski, G Saksena, ...
PloS one 9 (1), e87361, 2014
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state
Y Li, PS Choi, SC Casey, DL Dill, DW Felsher
Cancer cell 26 (2), 262-272, 2014
P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrowhematopoietic stem cells
BC Lee, T Cheng, GB Adams, EC Attar, N Miura, SB Lee, Y Saito, I Olszak, ...
Genes & development 17 (13), 1592-1604, 2003
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance
J Van Riggelen, J Müller, T Otto, V Beuger, A Yetil, PS Choi, C Kosan, ...
Genes & development 24 (12), 1281-1294, 2010
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells
HS Gannon, T Zou, MK Kiessling, GF Gao, D Cai, PS Choi, AP Ivan, ...
Nature communications 9 (1), 1-10, 2018
Somatic superenhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor
X Zhang, PS Choi, JM Francis, GF Gao, JD Campbell, A Ramachandran, ...
Cancer discovery 8 (1), 108-125, 2018
Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability
BR Paolella, WJ Gibson, LM Urbanski, JA Alberta, TI Zack, ...
Elife 6, e23268, 2017
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics
L De Waal, TA Lewis, MG Rees, A Tsherniak, X Wu, PS Choi, L Gechijian, ...
Nature chemical biology 12 (2), 102-108, 2016
Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction
PS Choi, J Van Riggelen, AJ Gentles, P Bachireddy, K Rakhra, SJ Adam, ...
Proceedings of the National Academy of Sciences 108 (42), 17432-17437, 2011
Survival and death signals can predict tumor response to therapy after oncogene inactivation
PT Tran, PK Bendapudi, HJ Lin, P Choi, S Koh, J Chen, G Horng, ...
Science translational medicine 3 (103), 103ra99-103ra99, 2011
MET exon 14 mutation encodes an actionable therapeutic target in lung adenocarcinoma
X Lu, N Peled, J Greer, W Wu, P Choi, AH Berger, S Wong, KY Jen, Y Seo, ...
Cancer research 77 (16), 4498-4505, 2017
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer
J Li, PS Choi, CL Chaffer, K Labella, JH Hwang, AO Giacomelli, JW Kim, ...
Elife 7, e37184, 2018
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer
SR Viswanathan, MF Nogueira, CG Buss, JM Krill-Burger, MJ Wawer, ...
Nature genetics 50 (7), 937-943, 2018
Activation of Cre recombinase alone can induce complete tumor regression
Y Li, PS Choi, SC Casey, DW Felsher
PLoS One 9 (9), e107589, 2014
Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function
A Craiu, Y Saito, A Limon, HM Eppich, DP Olson, N Rodrigues, GB Adams, ...
Blood 105 (5), 2235-2238, 2005
BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia
Y Li, A Deutzmann, PS Choi, AC Fan, DW Felsher
Oncotarget 7 (19), 26926, 2016
Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance
PS Choi, Y Li, DW Felsher
Proceedings of the National Academy of Sciences 111 (32), E3316-E3324, 2014
Identification and characterization of oncogenic SOS1 mutations in lung adenocarcinoma
D Cai, PS Choi, M Gelbard, M Meyerson
Molecular Cancer Research 17 (4), 1002-1012, 2019
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