Structure of replicating SARS-CoV-2 polymerase HS Hillen, G Kokic, L Farnung, C Dienemann, D Tegunov, P Cramer Nature 584 (7819), 154-156, 2020 | 757 | 2020 |
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir G Kokic, HS Hillen, D Tegunov, C Dienemann, F Seitz, J Schmitzova, ... Nature communications 12 (1), 1-7, 2021 | 534 | 2021 |
Structure of activated transcription complex Pol II–DSIF–PAF–SPT6 SM Vos, L Farnung, M Boehning, C Wigge, A Linden, H Urlaub, P Cramer Nature 560 (7720), 607-612, 2018 | 362 | 2018 |
Structure of paused transcription complex Pol II–DSIF–NELF SM Vos, L Farnung, H Urlaub, P Cramer Nature 560 (7720), 601-606, 2018 | 327 | 2018 |
The interaction landscape between transcription factors and the nucleosome F Zhu, L Farnung, E Kaasinen, B Sahu, Y Yin, B Wei, SO Dodonova, ... Nature 562 (7725), 76-81, 2018 | 302 | 2018 |
Nucleosome–Chd1 structure and implications for chromatin remodelling L Farnung, SM Vos, C Wigge, P Cramer Nature 550 (7677), 539-542, 2017 | 226 | 2017 |
The structure and substrate specificity of human Cdk12/Cyclin K CA Bösken, L Farnung, C Hintermair, M Merzel Schachter, ... Nature communications 5 (1), 3505, 2014 | 189 | 2014 |
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation SM Vos, L Farnung, A Linden, H Urlaub, P Cramer Nature Structural & Molecular Biology 27 (7), 668-677, 2020 | 114 | 2020 |
Structure of transcribing RNA polymerase II-nucleosome complex L Farnung, SM Vos, P Cramer Nature communications 9 (1), 5432, 2018 | 98 | 2018 |
Structural basis of nucleosome transcription mediated by Chd1 and FACT L Farnung, M Ochmann, M Engeholm, P Cramer Nature Structural & Molecular Biology 28 (4), 382-387, 2021 | 86 | 2021 |
Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations L Farnung, M Ochmann, P Cramer eLife 9, e56178, 2020 | 64* | 2020 |
Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding H Wang, L Farnung, C Dienemann, P Cramer Nature structural & molecular biology 27 (1), 8-13, 2020 | 64 | 2020 |
Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo K Žumer, KC Maier, L Farnung, MG Jaeger, P Rus, G Winter, P Cramer Molecular Cell 81 (15), 3096-3109. e8, 2021 | 63 | 2021 |
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing E Oberbeckmann, V Niebauer, S Watanabe, L Farnung, M Moldt, ... Nature Communications 12 (1), 3232, 2021 | 50 | 2021 |
Structural basis of nucleosome retention during transcription elongation M Filipovski, JHM Soffers, SM Vos, L Farnung Science 376 (6599), 1313-1316, 2022 | 47 | 2022 |
Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin X Liu, L Farnung, C Wigge, P Cramer Journal of Biological Chemistry 293 (19), 7189-7194, 2018 | 40 | 2018 |
Structure of a backtracked hexasomal intermediate of nucleosome transcription L Farnung, M Ochmann, G Garg, SM Vos, P Cramer Molecular Cell 82 (17), 3126-3134. e7, 2022 | 36 | 2022 |
Assembly of RNA polymerase II transcription initiation complexes L Farnung, SM Vos Current opinion in structural biology 73, 102335, 2022 | 22 | 2022 |
Nucleosomal arrangement affects single-molecule transcription dynamics V Fitz, J Shin, C Ehrlich, L Farnung, P Cramer, V Zaburdaev, SW Grill Proceedings of the National Academy of Sciences 113 (45), 12733-12738, 2016 | 21 | 2016 |
Mechanism of RNA polymerase II stalling by DNA alkylation S Malvezzi, L Farnung, CMN Aloisi, T Angelov, P Cramer, SJ Sturla Proceedings of the National Academy of Sciences 114 (46), 12172-12177, 2017 | 15 | 2017 |