Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform C Denning, V Borgdorff, J Crutchley, KSA Firth, V George, S Kalra, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1728-1748, 2016 | 333 | 2016 |
Polymer–lipid nanoparticles for systemic delivery of mRNA to the lungs JC Kaczmarek, AK Patel, KJ Kauffman, OS Fenton, MJ Webber, ... Angewandte Chemie International Edition 55 (44), 13808-13812, 2016 | 292 | 2016 |
Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium AK Patel, JC Kaczmarek, S Bose, KJ Kauffman, F Mir, MW Heartlein, ... Advanced Materials 31 (8), 1805116, 2019 | 281 | 2019 |
Optimization of a Degradable Polymer–Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells JC Kaczmarek, KJ Kauffman, OS Fenton, K Sadtler, AK Patel, ... Nano letters 18 (10), 6449-6454, 2018 | 167 | 2018 |
Current status of drug screening and disease modelling in human pluripotent stem cells D Rajamohan, E Matsa, S Kalra, J Crutchley, A Patel, V George, ... Bioessays 35 (3), 281-298, 2013 | 124 | 2013 |
Discovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation AD Celiz, JGW Smith, AK Patel, AL Hook, D Rajamohan, VT George, ... Advanced Materials 27 (27), 4006-4012, 2015 | 90 | 2015 |
A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials … AK Patel, AD Celiz, D Rajamohan, DG Anderson, R Langer, MC Davies, ... Biomaterials 61, 257-265, 2015 | 74 | 2015 |
Systemic Delivery of mRNA and DNA to the Lung using Polymer-Lipid Nanoparticles JC Kaczmarek, AK Patel, LH Rhym, UC Palmiero, B Bhat, MW Heartlein, ... Biomaterials, 120966, 2021 | 67 | 2021 |
Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits JGW Smith, T Owen, JR Bhagwan, D Mosqueira, E Scott, I Mannhardt, ... Stem cell reports 11 (5), 1226-1243, 2018 | 60 | 2018 |
High throughput screening for discovery of materials that control stem cell fate AK Patel, MW Tibbitt, AD Celiz, MC Davies, R Langer, C Denning, ... Current Opinion in Solid State and Materials Science 20 (4), 202-211, 2016 | 48 | 2016 |
Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture AD Celiz, JGW Smith, AK Patel, R Langer, DG Anderson, DA Barrett, ... Biomaterials science 2 (11), 1604-1611, 2014 | 45 | 2014 |
Drug delivery across length scales D Delcassian, AK Patel, AB Cortinas, R Langer Journal of drug targeting 27 (3), 229-243, 2019 | 27 | 2019 |
Nanotechnology and drug delivery D Delcassian, AK Patel Bioengineering Innovative Solutions for Cancer, 197-219, 2020 | 7 | 2020 |
Scaling human pluripotent stem cell expansion and differentiation: are cell factories becoming a reality? JGW Smith, AD Celiz, AK Patel, RD Short, MR Alexander, C Denning Regenerative medicine 10 (8), 925-930, 2015 | 6 | 2015 |
The early career researcher's toolkit: translating tissue engineering, regenerative medicine and cell therapy products QA Rafiq, I Ortega, SI Jenkins, SL Wilson, AK Patel, AL Barnes, CF Adams, ... Regenerative medicine 10 (8), 989-1003, 2015 | 5 | 2015 |
Poly (beta-amino esters) and uses thereof DG Anderson, KJ Kauffman, JC Kaczmarek, AK Patel US Patent App. 16/170,318, 2019 | 3 | 2019 |
Gene Delivery: Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium (Adv. Mater. 8/2019) AK Patel, JC Kaczmarek, S Bose, KJ Kauffman, F Mir, MW Heartlein, ... Advanced Materials 31 (8), 1970053, 2019 | 1 | 2019 |
Cell culture substrate MR Alexander, C Denning, L Young, A Celiz, J Smith, MC Davies, A Patel US Patent App. 15/510,556, 2017 | 1 | 2017 |
POLYMER-LIPIDS AND COMPOSITIONS JC Kaczmarek, DG Anderson, LH Rhym, KJ Kauffman, AK Patel US Patent App. 16/663,585, 2020 | | 2020 |
Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs MW Heartlein, F DeRosa, JC Kaczmarek, AK Patel, KJ Kauffman, ... Wiley Blackwell, 2016 | | 2016 |