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Karen Yu
Karen Yu
Global Blood Therapeutics
Verified email at gbt.com
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Cited by
Year
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
76972012
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment
HF Clark, AL Gurney, E Abaya, K Baker, D Baldwin, J Brush, J Chen, ...
Genome research 13 (10), 2265-2270, 2003
5112003
A highly conserved enhancer in the Dlx5/Dlx6Intergenic region is the site of cross-regulatory interactions betweenDlx genes in the embryonic forebrain
T Zerucha, T Stühmer, G Hatch, BK Park, Q Long, G Yu, A Gambarotta, ...
Journal of neuroscience 20 (2), 709-721, 2000
4102000
DLX‐1, DLX‐2, and DLX‐5 expression define distinct stages of basal forebrain differentiation
DD Eisenstat, JK Liu, M Mione, W Zhong, G Yu, SA Anderson, I Ghattas, ...
Journal of Comparative Neurology 414 (2), 217-237, 1999
3461999
Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition
J Murai, Y Feng, KY Guoying, Y Ru, SW Tang, Y Shen, Y Pommier
Oncotarget 7 (47), 76534, 2016
2582016
Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer
CA Stewart, P Tong, RJ Cardnell, T Sen, L Li, CM Gay, F Masrorpour, ...
Oncotarget 8 (17), 28575, 2017
1792017
Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism
H Lu, Y Xue, GK Yu, C Arias, J Lin, S Fong, M Faure, B Weisburd, X Ji, ...
Elife 4, e06535, 2015
1362015
The Novel Oral Hsp90 Inhibitor NVP-HSP990 Exhibits Potent and Broad-spectrum Antitumor Activities In Vitro and In Vivo
DL Menezes, P Taverna, MR Jensen, T Abrams, D Stuart, GK Yu, D Duhl, ...
Molecular cancer therapeutics 11 (3), 730-739, 2012
922012
Novel compositions and methods in cancer
A Lai, A Fanidi, R Booher, G Yu, E Moler, M Rowe
US Patent App. 11/403,116, 2007
912007
The essential transcription factor, Mcm1, is a downstream target of Sln1, a yeast" two-component" regulator
G Yu, RJ Deschenes, JS Fassler
Journal of Biological Chemistry 270 (15), 8739-8743, 1995
511995
SPT13 (GAL11) of Saccharomyces cerevisiae negatively regulates activity of the MCM1 transcription factor in Ty1 elements
G Yu, JS Fassler
Molecular and cellular biology, 1993
501993
Evidence that GRIP, a PDZ-domain protein which is expressed in the embryonic forebrain, co-activates transcription with DLX homeodomain proteins
G Yu, T Zerucha, M Ekker, JLR Rubenstein
Developmental Brain Research 130 (2), 217-230, 2001
462001
The Saccharomyces cerevisiae SPT14 gene is essential for normal expression of the yeast transposon, Ty, as well as for expression of the HIS4 gene and several …
JS Fassler, W Gray, JP Lee, G Yu, G Gingerich
Molecular and General Genetics MGG 230, 310-320, 1991
441991
SEMA4D in cancer diagnosis, detection and treatment
A Lai, A Fanidi, R Booher, C Tse, X Xu, G Yu, E Moler, M Rowe
US Patent 7,919,246, 2011
252011
Induction of ER stress by an AAV5 BDD FVIII construct is dependent on the strength of the hepatic-specific promoter
S Fong, B Handyside, CR Sihn, S Liu, L Zhang, L Xie, R Murphy, ...
Molecular Therapy-Methods & Clinical Development 18, 620-630, 2020
242020
Neurofilament light is a treatment‐responsive biomarker in CLN2 disease
Y Ru, C Corado, RK Soon Jr, AC Melton, A Harris, GK Yu, N Pryer, ...
Annals of Clinical and Translational Neurology 6 (12), 2437-2447, 2019
242019
Assessment of predicted enzymatic activity of α‐N‐acetylglucosaminidase variants of unknown significance for CAGI 2016
WT Clark, L Kasak, C Bakolitsa, Z Hu, G Andreoletti, G Babbi, Y Bromberg, ...
Human mutation 40 (9), 1519-1529, 2019
142019
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidence
WT Clark, GK Yu, M Aoyagi-Scharber, JH LeBowitz
PLoS One 13 (7), e0200008, 2018
142018
Novel compositions and methods in cancer
G Yu, E Moler, M Rowe
US Patent App. 11/408,131, 2007
112007
Identifying therapeutic drug targets using bidirectional effect genes
K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ...
Nature Communications 12 (1), 2224, 2021
102021
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