Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response L Westerberg, M Larsson, SJ Hardy, C Fernández, AJ Thrasher, ... Blood 105 (3), 1144-1152, 2005 | 185 | 2005 |
CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment SY Neo, Y Yang, J Record, R Ma, X Chen, Z Chen, NP Tobin, E Blake, ... The Journal of clinical investigation 130 (3), 1185-1198, 2020 | 161 | 2020 |
WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function LS Westerberg, MA de la Fuente, F Wermeling, HD Ochs, MCI Karlsson, ... Blood, The Journal of the American Society of Hematology 112 (10), 4139-4147, 2008 | 137 | 2008 |
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice M Recher, SO Burns, MA de la Fuente, S Volpi, C Dahlberg, JE Walter, ... Blood, The Journal of the American Society of Hematology 119 (12), 2819-2828, 2012 | 124 | 2012 |
Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes L Westerberg, G Greicius, SB Snapper, P Aspenström, E Severinson Blood, The Journal of the American Society of Hematology 98 (4), 1086-1094, 2001 | 119 | 2001 |
Wiskott–Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development V Cotta-de-Almeida, L Westerberg, MH Maillard, D Onaldi, H Wachtel, ... Proceedings of the National Academy of Sciences 104 (39), 15424-15429, 2007 | 117 | 2007 |
Pharmacologic activation of p53 triggers viral mimicry response thereby abolishing tumor immune evasion and promoting antitumor immunity X Zhou, M Singh, G Sanz Santos, V Guerlavais, LA Carvajal, M Aivado, ... Cancer discovery 11 (12), 3090-3105, 2021 | 91 | 2021 |
N-wasp is essential for the negative regulation of B cell receptor signaling C Liu, X Bai, J Wu, S Sharma, A Upadhyaya, CIM Dahlberg, ... PLoS biology 11 (11), e1001704, 2013 | 89 | 2013 |
Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function LS Westerberg, C Dahlberg, M Baptista, CJ Moran, C Detre, M Keszei, ... Blood, The Journal of the American Society of Hematology 119 (17), 3966-3974, 2012 | 87 | 2012 |
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes LS Westerberg, P Meelu, M Baptista, MA Eston, DA Adamovich, ... Journal of Experimental Medicine 207 (6), 1145-1152, 2010 | 81 | 2010 |
Phosphorylation of WASp is a key regulator of activity and stability in vivo MP Blundell, G Bouma, J Metelo, A Worth, Y Calle, LA Cowell, ... Proceedings of the National Academy of Sciences 106 (37), 15738-15743, 2009 | 72 | 2009 |
Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency—lessons learned from monogenic disorders in mice and men LS Westerberg, C Klein, SB Snapper Current opinion in immunology 20 (6), 646-654, 2008 | 72 | 2008 |
H1N1 vaccination in Sjögren’s syndrome triggers polyclonal B cell activation and promotes autoantibody production S Brauner, L Folkersen, M Kvarnström, S Meisgen, S Petersen, ... Annals of the rheumatic diseases 76 (10), 1755-1763, 2017 | 68 | 2017 |
Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells PP Lee, D Lobato-Márquez, N Pramanik, A Sirianni, V Daza-Cajigal, ... Nature communications 8 (1), 1576, 2017 | 61 | 2017 |
Foxp3 lacking exons 2 and 7 is unable to confer suppressive ability to regulatory T cells in vivo AL Joly, S Liu, CIM Dahlberg, RKW Mailer, LS Westerberg, J Andersson Journal of autoimmunity 63, 23-30, 2015 | 54 | 2015 |
Alternative Splicing of FOXP3 Controls Regulatory T Cell Effector Functions and Is Associated With Human Atherosclerotic Plaque Stability AL Joly, C Seitz, S Liu, NV Kuznetsov, K Gertow, LS Westerberg, ... Circulation research 122 (10), 1385-1394, 2018 | 52 | 2018 |
Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott–Aldrich syndrome protein L Westerberg, RPA Wallin, G Greicius, HG Ljunggren, E Severinson Immunology 109 (3), 384-391, 2003 | 49 | 2003 |
Microvilli structures on B lymphocytes: inducible functional domains? G Greicius, L Westerberg, EJ Davey, E Buentke, A Scheynius, J Thyberg, ... International immunology 16 (2), 353-364, 2004 | 46 | 2004 |
Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive M Keszei, J Record, JS Kritikou, H Wurzer, C Geyer, M Thiemann, ... The Journal of clinical investigation 128 (9), 4115-4131, 2018 | 45 | 2018 |
SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism Y Jing, L Luo, Y Chen, LS Westerberg, P Zhou, Z Xu, AA Herrada, ... Signal Transduction and Targeted Therapy 6 (1), 1-13, 2021 | 43 | 2021 |