| Targeting an RNA-binding protein network in acute myeloid leukemia E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ... Cancer cell 35 (3), 369-384. e7, 2019 | 248 | 2019 |
| Synthetic lethal and convergent biological effects of cancer-associated spliceosomal gene mutations SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ... Cancer cell 34 (2), 225-241. e8, 2018 | 208 | 2018 |
| Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations D Inoue, J Kitaura, K Togami, K Nishimura, Y Enomoto, T Uchida, ... The Journal of clinical investigation 123 (11), 4627-4640, 2013 | 194 | 2013 |
| Spliceosomal disruption of the non-canonical BAF complex in cancer D Inoue, GL Chew, B Liu, BC Michel, J Pangallo, AR D’Avino, T Hitchman, ... Nature 574 (7778), 432-436, 2019 | 182 | 2019 |
| Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 177 | 2019 |
| Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, ... Journal of Experimental Medicine 215 (6), 1729-1747, 2018 | 139 | 2018 |
| Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis D Inoue, RK Bradley, O Abdel-Wahab Genes & development 30 (9), 989-1001, 2016 | 120 | 2016 |
| Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis S Asada, S Goyama, D Inoue, S Shikata, R Takeda, T Fukushima, ... Nature communications 9 (1), 2733, 2018 | 110 | 2018 |
| SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS D Inoue, J Kitaura, H Matsui, HA Hou, WC Chou, A Nagamachi, ... Leukemia 29 (4), 847-857, 2015 | 88 | 2015 |
| Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ... Nature genetics 53 (5), 707-718, 2021 | 75 | 2021 |
| Altered nuclear export signal recognition as a driver of oncogenesis J Taylor, M Sendino, AN Gorelick, A Pastore, MT Chang, AV Penson, ... Cancer discovery 9 (10), 1452-1467, 2019 | 71 | 2019 |
| Excellent therapeutic effect of tocilizumab on intestinal amyloid a deposition secondary to active rheumatoid arthritis D Inoue, H Arima, C Kawanami, Y Takiuchi, S Nagano, T Kimura, ... Clinical rheumatology 29, 1195-1197, 2010 | 70 | 2010 |
| Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels D Inoue, M Matsumoto, R Nagase, M Saika, T Fujino, KI Nakayama, ... Experimental hematology 44 (3), 172-176. e1, 2016 | 68 | 2016 |
| Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway T Fujino, S Goyama, Y Sugiura, D Inoue, S Asada, S Yamasaki, ... Nature communications 12 (1), 1826, 2021 | 66 | 2021 |
| Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies J Taylor, D Pavlick, A Yoshimi, C Marcelus, SS Chung, JF Hechtman, ... The Journal of clinical investigation 128 (9), 3819-3825, 2018 | 62 | 2018 |
| A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies D Inoue, T Fujino, P Sheridan, Y Zhang, R Nagase, S Horikawa, Z Li, ... Leukemia 32 (6), 1327-1337, 2018 | 62 | 2018 |
| ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia JB Micol, A Pastore, D Inoue, N Duployez, E Kim, SCW Lee, BH Durham, ... Nature communications 8 (1), 15429, 2017 | 61 | 2017 |
| Biological implications of somatic DDX41 p. R525H mutation in acute myeloid leukemia M Kadono, A Kanai, A Nagamachi, S Shinriki, J Kawata, K Iwato, T Kyo, ... Experimental Hematology 44 (8), 745-754. e4, 2016 | 59 | 2016 |
| IP-10/CXCL10 and MIG/CXCL9 as novel markers for the diagnosis of lymphoma-associated hemophagocytic syndrome H Maruoka, D Inoue, Y Takiuchi, S Nagano, H Arima, S Tabata, ... Annals of Hematology 93, 393-401, 2014 | 54 | 2014 |
| Fulminant sepsis caused by Bacillus cereus in patients with hematologic malignancies: analysis of its prognosis and risk factors D Inoue, Y Nagai, M Mori, S Nagano, Y Takiuchi, H Arima, T Kimura, ... Leukemia & lymphoma 51 (5), 860-869, 2010 | 48 | 2010 |
