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Iris Lindberg
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The crystal structure of the proprotein processing proteinase furin explains its stringent specificity
S Henrich, A Cameron, GP Bourenkov, R Kiefersauer, R Huber, ...
Nature Structural & Molecular Biology 10 (7), 520-526, 2003
4302003
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
X Zhu, A Zhou, A Dey, C Norrbom, R Carroll, C Zhang, V Laurent, ...
Proceedings of the National Academy of Sciences 99 (16), 10293-10298, 2002
4252002
Polyarginines are potent furin inhibitors
A Cameron, J Appel, RA Houghten, I Lindberg
Journal of Biological Chemistry 275 (47), 36741-36749, 2000
2682000
Purification and characterization of the prohormone convertase PC1 (PC3).
Y Zhou, I Lindberg
Journal of Biological Chemistry 268 (8), 5615-5623, 1993
2131993
The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing’s disease
CH Westphal, L Muller, A Zhou, X Zhu, S Bonner-Weir, M Schambelan, ...
Cell 96 (5), 689-700, 1999
2121999
Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity
S Henrich, I Lindberg, W Bode, ME Than
Journal of molecular biology 345 (2), 211-227, 2005
1932005
Prodynorphin processing by proprotein convertase 2: cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity
R Day, C Lazure, A Basak, A Boudreault, P Limperis, W Dong, I Lindberg
Journal of Biological Chemistry 273 (2), 829-836, 1998
1911998
7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity.
X Zhu, I Lindberg
The Journal of cell biology 129 (6), 1641-1650, 1995
1781995
The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2.
GJ Martens, JA Braks, DW Eib, Y Zhou, I Lindberg
Proceedings of the National Academy of Sciences 91 (13), 5784-5787, 1994
1771994
Differential processing of proenkephalin by prohormone convertases 1 (3) and 2 and furin.
MB Breslin, I Lindberg, S Benjannet, JP Mathis, C Lazure, NG Seidah
Journal of Biological Chemistry 268 (36), 27084-27093, 1993
1731993
The cell biology of the prohormone convertases PCI and PC2
L Muller, I Lindberg
Progress in nucleic acid research and molecular biology 63, 69-108, 1999
1621999
Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells.
O Vindrola, I Lindberg
Molecular Endocrinology 6 (7), 1088-1094, 1992
1531992
Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort
MG Martín, I Lindberg, RS Solorzano–Vargas, J Wang, Y Avitzur, ...
Gastroenterology 145 (1), 138-148, 2013
1522013
Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine
MM Kacprzak, JR Peinado, ME Than, J Appel, S Henrich, G Lipkind, ...
Journal of Biological Chemistry 279 (35), 36788-36794, 2004
1442004
Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics
GL Becker, F Sielaff, ME Than, I Lindberg, S Routhier, R Day, Y Lu, ...
Journal of medicinal chemistry 53 (3), 1067-1075, 2010
1262010
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
GL Becker, Y Lu, K Hardes, B Strehlow, C Levesque, I Lindberg, ...
Journal of Biological Chemistry 287 (26), 21992-22003, 2012
1252012
Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates
K Johanning, MA Juliano, L Juliano, C Lazure, NS Lamango, DF Steiner, ...
Journal of Biological Chemistry 273 (35), 22672-22680, 1998
1201998
Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding
L Muller, X Zhu, I Lindberg
The Journal of cell biology 139 (3), 625-638, 1997
1181997
Purification and enzymatic characterization of recombinant prohormone convertase 2: stabilization of activity by 21 kDa 7B2
NS Lamango, X Zhu, I Lindberg
Archives of biochemistry and biophysics 330 (2), 238-250, 1996
1101996
Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase
SA Shiryaev, BI Ratnikov, AV Chekanov, S Sikora, DV Rozanov, A Godzik, ...
Biochemical Journal 393 (2), 503-511, 2006
1072006
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