| Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase A Chabes, B Georgieva, V Domkin, X Zhao, R Rothstein, L Thelander Cell 112 (3), 391-401, 2003 | 544 | 2003 |
| Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases SA Nick McElhinny, BE Watts, D Kumar, DL Watt, EB Lundström, ... Proceedings of the National Academy of Sciences 107 (11), 4949-4954, 2010 | 462 | 2010 |
| Genome instability due to ribonucleotide incorporation into DNA SAN McElhinny, D Kumar, AB Clark, DL Watt, BE Watts, EB Lundström, ... Nature chemical biology 6 (10), 774-781, 2010 | 434 | 2010 |
| SAMHD1 acts at stalled replication forks to prevent interferon induction F Coquel, MJ Silva, H Técher, K Zadorozhny, S Sharma, J Nieminuszczy, ... Nature 557 (7703), 57-61, 2018 | 382 | 2018 |
| The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage X Zhao, A Chabes, V Domkin, L Thelander, R Rothstein The EMBO journal, 2001 | 356 | 2001 |
| dNTP pools determine fork progression and origin usage under replication stress J Poli, O Tsaponina, L Crabbé, A Keszthelyi, V Pantesco, A Chabes, ... The EMBO journal 31 (4), 883-894, 2012 | 335 | 2012 |
| Break-induced replication is highly inaccurate A Deem, A Keszthelyi, T Blackgrove, A Vayl, B Coffey, R Mathur, ... PLoS biology 9 (2), e1000594, 2011 | 328 | 2011 |
| Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and … A Chabes, L Thelander Journal of Biological Chemistry 275 (23), 17747-17753, 2000 | 233 | 2000 |
| Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools D Kumar, AL Abdulovic, J Viberg, AK Nilsson, TA Kunkel, A Chabes Nucleic acids research 39 (4), 1360-1371, 2011 | 210 | 2011 |
| A mechanism for preventing asymmetric histone segregation onto replicating DNA strands C Yu, H Gan, A Serra-Cardona, L Zhang, S Gan, S Sharma, E Johansson, ... Science 361 (6409), 1386-1389, 2018 | 190 | 2018 |
| Yeast Sml1, a protein inhibitor of ribonucleotide reductase A Chabes, V Domkin, L Thelander Journal of Biological Chemistry 274 (51), 36679-36683, 1999 | 189 | 1999 |
| Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall C Yu, H Gan, J Han, ZX Zhou, S Jia, A Chabes, G Farrugia, T Ordog, ... Molecular cell 56 (4), 551-563, 2014 | 185 | 2014 |
| Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA JS Williams, DJ Smith, L Marjavaara, SA Lujan, A Chabes, TA Kunkel Molecular cell 49 (5), 1010-1015, 2013 | 168 | 2013 |
| Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae A Chabes, B Stillman Proceedings of the National Academy of Sciences 104 (4), 1183-1188, 2007 | 168 | 2007 |
| Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint D Kumar, J Viberg, AK Nilsson, A Chabes Nucleic acids research 38 (12), 3975-3983, 2010 | 164 | 2010 |
| Cid13 is a cytoplasmic poly (A) polymerase that regulates ribonucleotide reductase mRNA S Saitoh, A Chabes, WH McDonald, L Thelander, JR Yates, P Russell Cell 109 (5), 563-573, 2002 | 159 | 2002 |
| Rnr4p, a novel ribonucleotide reductase small-subunit protein PJ Wang, A Chabes, R Casagrande, XC Tian, L Thelander, TC Huffaker Molecular and cellular biology, 1997 | 149 | 1997 |
| Trypanosoma brucei CTP synthetase: A target for the treatment of African sleeping sickness A Hofer, D Steverding, A Chabes, R Brun, L Thelander Proceedings of the National Academy of Sciences 98 (11), 6412-6416, 2001 | 142 | 2001 |
| Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype MB Davidson, Y Katou, A Keszthelyi, TL Sing, T Xia, J Ou, JA Vaisica, ... The EMBO journal 31 (4), 895-907, 2012 | 135 | 2012 |
| Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance M Rentoft, K Lindell, P Tran, AL Chabes, RJ Buckland, DL Watt, ... Proceedings of the National Academy of Sciences 113 (17), 4723-4728, 2016 | 129 | 2016 |
Erik JohanssonUmeå UniversityVerified email at umu.se
