Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains Y Su, WRG Dostmann, FW Herberg, K Durick, NH Xuong, L Ten Eyck, ... Science 269 (5225), 807-813, 1995 | 477 | 1995 |
Spatiotemporal dynamics of guanosine 3′, 5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator A Honda, SR Adams, CL Sawyer, V Lev-Ram, RY Tsien, WRG Dostmann Proceedings of the National Academy of Sciences 98 (5), 2437-2442, 2001 | 349 | 2001 |
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease DI Lee, G Zhu, T Sasaki, GS Cho, N Hamdani, R Holewinski, SH Jo, ... Nature 519 (7544), 472-476, 2015 | 340 | 2015 |
Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway M Mongillo, CG Tocchetti, A Terrin, V Lissandron, YF Cheung, ... Circulation research 98 (2), 226-234, 2006 | 317 | 2006 |
Structure and function of cGMP-dependent protein kinases A Pfeifer, P Ruth, W Dostmann, M Sausbier, P Klatt, F Hofmann Reviews of Physiology, Biochemistry and Pharmacology, Volume 135, 105-149, 2005 | 286 | 2005 |
p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process CB Zhu, AM Carneiro, WR Dostmann, WA Hewlett, RD Blakely Journal of Biological Chemistry 280 (16), 15649-15658, 2005 | 258 | 2005 |
cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism E Takimoto, HC Champion, D Belardi, J Moslehi, M Mongillo, E Mergia, ... Circulation research 96 (1), 100-109, 2005 | 254 | 2005 |
Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3', 5'-cyclic phosphorothioates. WR Dostmann, SS Taylor, HG Genieser, B Jastorff, SO Døskeland, ... Journal of Biological Chemistry 265 (18), 10484-10491, 1990 | 245 | 1990 |
Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors LWM Nausch, J Ledoux, AD Bonev, MT Nelson, WR Dostmann Proceedings of the National Academy of Sciences 105 (1), 365-370, 2008 | 206 | 2008 |
Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iα inhibit NO-induced cerebral dilation WRG Dostmann, MS Taylor, CK Nickl, JE Brayden, R Frank, WJ Tegge Proceedings of the National Academy of Sciences 97 (26), 14772-14777, 2000 | 199 | 2000 |
Structure and physiological role of cGMP-dependent protein kinase F Hofmann, W Dostmann, A Keilbach, W Landgraf, P Ruth Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1135 (1), 51-60, 1992 | 160 | 1992 |
Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase FW Herberg, SS Taylor, WRG Dostmann Biochemistry 35 (9), 2934-2942, 1996 | 157 | 1996 |
Determination of cyclic nucleotide-dependent protein kinase substrate specificity by the use of peptide libraries on cellulose paper W Tegge, R Frank, F Hofmann, WRG Dostmann Biochemistry 34 (33), 10569-10577, 1995 | 155 | 1995 |
Nitric oxide promotes airway epithelial wound repair through enhanced activation of MMP-9 PF Bove, UV Wesley, AK Greul, M Hristova, WR Dostmann, ... American journal of respiratory cell and molecular biology 36 (2), 138-146, 2007 | 127 | 2007 |
Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart CL Miller, Y Cai, M Oikawa, T Thomas, WR Dostmann, M Zaccolo, ... Basic research in cardiology 106, 1023-1039, 2011 | 123 | 2011 |
Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors AM Batchelor, K Bartus, C Reynell, S Constantinou, EJ Halvey, KF Held, ... Proceedings of the National Academy of Sciences 107 (51), 22060-22065, 2010 | 117 | 2010 |
Identifying the molecular switches that determine whether (Rp)-cAMPS functions as an antagonist or an agonist in the activation of cAMP-dependent protein kinase I WRG Dostmann, SS Taylor Biochemistry 30 (35), 8710-8716, 1991 | 115 | 1991 |
Crosstalk between domains in the regulatory subunit of cAMP-dependent protein kinase: influence of amino terminus on cAMP binding and holoenzyme formation FW Herberg, WRG Dostmann, M Zorn, SJ Davis, SS Taylor Biochemistry 33 (23), 7485-7494, 1994 | 106 | 1994 |
(R P)‐cAMPS inhibits the cAMP‐dependent protein kinase by blocking the cAMP‐induced conformational transition WRG Dostmann FEBS letters 375 (3), 231-234, 1995 | 90 | 1995 |
Cell-permeable non-hydrolyzable cAMP derivatives as tools for analysis of signaling pathways controlling gene regulation in Dictyostelium. P Schaap, M van Ments-Cohen, RD Soede, R Brandt, RA Firtel, ... Journal of Biological Chemistry 268 (9), 6323-6331, 1993 | 90 | 1993 |