Concentration dependent viscosity of monoclonal antibody solutions: explaining experimental behavior in terms of molecular properties L Li, S Kumar, PM Buck, C Burns, J Lavoie, SK Singh, NW Warne, ... Pharmaceutical research 31, 3161-3178, 2014 | 127 | 2014 |
Highly viscous antibody solutions are a consequence of network formation caused by domain–domain electrostatic complementarities: Insights from coarse-grained simulations PM Buck, A Chaudhri, S Kumar, SK Singh Molecular pharmaceutics 12 (1), 127-139, 2015 | 118 | 2015 |
Rational design of viscosity reducing mutants of a monoclonal antibody: hydrophobic versus electrostatic inter-molecular interactions P Nichols, L Li, S Kumar, PM Buck, SK Singh, S Goswami, B Balthazor, ... MAbs 7 (1), 212-230, 2015 | 95 | 2015 |
Computational tool for the early screening of monoclonal antibodies for their viscosities NJ Agrawal, B Helk, S Kumar, N Mody, HA Sathish, HS Samra, PM Buck, ... MAbs 8 (1), 43-48, 2016 | 89 | 2016 |
Computational methods to predict therapeutic protein aggregation PM Buck, S Kumar, X Wang, NJ Agrawal, BL Trout, SK Singh Therapeutic proteins: Methods and protocols, 425-451, 2012 | 65 | 2012 |
On the role of aggregation prone regions in protein evolution, stability, and enzymatic catalysis: insights from diverse analyses PM Buck, S Kumar, SK Singh PLoS computational biology 9 (10), e1003291, 2013 | 56 | 2013 |
Agitation-induced aggregation and subvisible particulate formation in model proteins M Jayaraman, PM Buck, AA Ignatius, KR King, W Wang European Journal of Pharmaceutics and Biopharmaceutics 87 (2), 299-309, 2014 | 42 | 2014 |
Impact of deglycosylation and thermal stress on conformational stability of a full length murine IgG2a monoclonal antibody: observations from molecular dynamics simulations X Wang, S Kumar, PM Buck, SK Singh Proteins: Structure, Function, and Bioinformatics 81 (3), 443-460, 2013 | 37 | 2013 |
Consequences of glycan truncation on Fc structural integrity PM Buck, S Kumar, SK Singh MAbs 5 (6), 904-916, 2013 | 36 | 2013 |
Insights into the potential aggregation liabilities of the b12 Fab fragment via elevated temperature molecular dynamics PM Buck, S Kumar, SK Singh Protein Engineering, Design & Selection 26 (3), 195-206, 2013 | 19 | 2013 |
Toward computationally designed self-reporting biosensors using leave-one-out green fluorescent protein Y Huang, S Banerjee, DE Crone, CD Schenkelberg, DJ Pitman, PM Buck, ... Biochemistry 54 (40), 6263-6273, 2015 | 14 | 2015 |
Simulating protein folding initiation sites using an alpha‐carbon‐only knowledge‐based force field PM Buck, C Bystroff Proteins: Structure, Function, and Bioinformatics 76 (2), 331-342, 2009 | 7 | 2009 |
Biopharmaceutical informatics: applications of computation in biologic drug development S Kumar, RH Robins, PM Buck, TP Hickling, AM Thangakani, L Li, ... Developability of Biotherapeutics: Computational Approaches, 3-34, 2015 | 6 | 2015 |
Constraining local structure can speed up folding by promoting structural polarization of the folding pathway PM Buck, C Bystroff Protein Science 20 (6), 959-969, 2011 | 5 | 2011 |
Computational tool for the early screening of monoclonal antibodies for their viscosities. mAbs 2016; 8: 43-8; PMID: 26399600 NJ Agrawal, B Helk, S Kumar, N Mody, HA Sathish, HS Samra, PM Buck, ... | 2 | |
PIH51 NON-CLINICAL FACTORS ARE THE KEY BARRIER FOR PATIENT ACCESS TO PENILE PROSTHESIS IN EMPLOYER-SPONSORED HEALTH INSURANCE https://www.valueinhealthjournal.com/article/S1098-3015(20)30634-3/fulltext, 2020 | | 2020 |
PHP255-EUROPEAN “REAL-WORLD” EVIDENCE FOR DRUGS AND DEVICES: 2017 LITERATURE REVIEWED M Mordin, C Castro, PM Buck, MM Fernandez, KA Hollis, ME Ritchey Value in Health 21, S193, 2018 | | 2018 |
What does “Real World” Evidence Mean? A Review of 2017 Literature M Mordin, PM Buck, C Castro, MM Fernandez, KA Hollis, ME Ritchey Value in Health 21, S108, 2018 | | 2018 |
Applications of Computation in Biologic Drug Development S Kumar, RH Robins, PM Buck, TP Hickling, AM Thangakani, L Li, ... Developability of Biotherapeutics: Computational Approaches, 1, 2015 | | 2015 |
Biopharmaceutical informatics: Understanding behavior of highly concentrated antibody solutions at molecular level via coarse-grained modeling and simulations DS Tomar, P Buck, S Kumar, S Singh ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |