The catalytic mechanisms of binuclear metallohydrolases N Mitić, SJ Smith, A Neves, LW Guddat, LR Gahan, G Schenk Chemical reviews 106 (8), 3338-3363, 2006 | 483 | 2006 |
Purple acid phosphatase: a journey into the function and mechanism of a colorful enzyme G Schenk, N Mitić, GR Hanson, P Comba Coordination Chemistry Reviews 257 (2), 473-482, 2013 | 215 | 2013 |
Phosphate forms an unusual tripodal complex with the Fe–Mn center of sweet potato purple acid phosphatase G Schenk, LR Gahan, LE Carrington, N Mitić, M Valizadeh, SE Hamilton, ... Proceedings of the National Academy of Sciences 102 (2), 273-278, 2005 | 170 | 2005 |
Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction G Schenk, N Mitic, LR Gahan, DL Ollis, RP McGeary, LW Guddat Accounts of Chemical Research 45 (9), 1593-1603, 2012 | 152 | 2012 |
Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle G Schenk, TW Elliott, E Leung, LE Carrington, N Mitić, LR Gahan, ... BMC structural biology 8, 1-13, 2008 | 113 | 2008 |
Organophosphate-degrading metallohydrolases: Structure and function of potent catalysts for applications in bioremediation G Schenk, I Mateen, TK Ng, MM Pedroso, N Mitić, M Jafelicci Jr, ... Coordination Chemistry Reviews 317, 122-131, 2016 | 91 | 2016 |
The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening P Vella, WM Hussein, EWW Leung, D Clayton, DL Ollis, N Mitić, G Schenk, ... Bioorganic & medicinal chemistry letters 21 (11), 3282-3285, 2011 | 87 | 2011 |
Spectroscopic characterization of the catalytically competent ferrous site of the resting, activated, and substrate-bound forms of phenylalanine hydroxylase KE Loeb, TE Westre, TJ Kappock, N Mitić, E Glasfeld, JP Caradonna, ... Journal of the American Chemical Society 119 (8), 1901-1915, 1997 | 87 | 1997 |
Catalytic mechanisms of metallohydrolases containing two metal ions N Mitić, M Miraula, C Selleck, KS Hadler, E Uribe, MM Pedroso, G Schenk Advances in protein chemistry and structural biology 97, 49-81, 2014 | 86 | 2014 |
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes KS Hadler, EA Tanifum, SHC Yip, N Mitic, LW Guddat, CJ Jackson, ... Journal of the American chemical society 130 (43), 14129-14138, 2008 | 86 | 2008 |
Spectroscopic and Electronic Structure Studies of Intermediate X in Ribonucleotide Reductase R2 and Two Variants: A Description of the FeIV-Oxo Bond in the FeIII−O−Fe … N Mitić, MD Clay, L Saleh, JM Bollinger, EI Solomon Journal of the American Chemical Society 129 (29), 9049-9065, 2007 | 81 | 2007 |
Circular dichroism and magnetic circular dichroism spectroscopy of the catalytically competent ferrous active site of phenylalanine hydroxylase and its interaction with pterin … JN Kemsley, N Mitić, KL Zaleski, JP Caradonna, EI Solomon Journal of the American Chemical Society 121 (7), 1528-1536, 1999 | 79 | 1999 |
Diesterase activity and substrate binding in purple acid phosphatases RS Cox, G Schenk, N Mitić, LR Gahan, AC Hengge Journal of the American Chemical Society 129 (31), 9550-9551, 2007 | 78 | 2007 |
Metal-ion mutagenesis: conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent … N Mitic, CJ Noble, LR Gahan, GR Hanson, G Schenk Journal of the American Chemical Society 131 (23), 8173-8179, 2009 | 74 | 2009 |
The reaction mechanism of the Ga (III) Zn (II) derivative of uteroferrin and corresponding biomimetics SJ Smith, A Casellato, KS Hadler, N Mitić, MJ Riley, AJ Bortoluzzi, ... JBIC Journal of Biological Inorganic Chemistry 12, 1207-1220, 2007 | 70 | 2007 |
The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis N Mitic, KS Hadler, LR Gahan, AC Hengge, G Schenk Journal of the American Chemical Society 132 (20), 7049-7054, 2010 | 69 | 2010 |
Human tartrate-resistant acid phosphatase becomes an effective ATPase upon proteolytic activation N Mitić, M Valizadeh, EWW Leung, J de Jersey, S Hamilton, DA Hume, ... Archives of biochemistry and biophysics 439 (2), 154-164, 2005 | 68 | 2005 |
Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis KS Hadler, N Mitic, F Ely, GR Hanson, LR Gahan, JA Larrabee, DL Ollis, ... Journal of the American Chemical Society 131 (33), 11900-11908, 2009 | 64 | 2009 |
Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site CJ Jackson, PD Carr, HK Kim, JW Liu, P Herrald, N Mitić, G Schenk, ... Biochemical Journal 397 (3), 501-508, 2006 | 60 | 2006 |
Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA) F Ely, KS Hadler, N Mitić, LR Gahan, DL Ollis, NM Plugis, MT Russo, ... JBIC Journal of Biological Inorganic Chemistry 16, 777-787, 2011 | 58 | 2011 |