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Santosh Kumar Padhi
Santosh Kumar Padhi
Associate Professor, Department of Biochemistry, School of Life Sciences, University of Hyderabad
Verified email at uohyd.ac.in - Homepage
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Year
Site-saturation mutagenesis of tryptophan 116 of Saccharomyces pastorianus old yellow enzyme uncovers stereocomplementary variants
SK Padhi, DJ Bougioukou, JD Stewart
Journal of the American Chemical Society 131 (9), 3271-3280, 2009
1772009
The α/β‐hydrolase fold 3DM database (ABHDB) as a tool for protein engineering
R Kourist, H Jochens, S Bartsch, R Kuipers, SK Padhi, M Gall, D Böttcher, ...
ChemBioChem 11 (12), 1635-1643, 2010
1632010
Discovery and protein engineering of biocatalysts for organic synthesis
GA Behrens, A Hummel, SK Padhi, S Schätzle, UT Bornscheuer
Advanced Synthesis & Catalysis 353 (13), 2191-2215, 2011
1412011
Protein engineering of α/β‐hydrolase fold enzymes
H Jochens, M Hesseler, K Stiba, SK Padhi, RJ Kazlauskas, ...
Chembiochem 12 (10), 1508-1517, 2011
1272011
Switching from an esterase to a hydroxynitrile lyase mechanism requires only two amino acid substitutions
SK Padhi, R Fujii, GA Legatt, SL Fossum, R Berchtold, RJ Kazlauskas
Chemistry & biology 17 (8), 863-871, 2010
632010
Microbial deracemisation of aromatic β-hydroxy acid esters
SK Padhi, NG Pandian, A Chadha
Journal of Molecular Catalysis B: Enzymatic 29 (1-6), 25-29, 2004
532004
Deracemisation of β-hydroxy esters using immobilised whole cells of Candida parapsilosis ATCC 7330: substrate specificity and mechanistic investigation
SK Padhi, D Titu, NG Pandian, A Chadha
Tetrahedron 62 (21), 5133-5140, 2006
492006
Altering the scissile fatty acid binding site of Candida antarctica lipase A by protein engineering for the selective hydrolysis of medium chain fatty acids
H Brundiek, SK Padhi, R Kourist, A Evitt, UT Bornscheuer
European Journal of Lipid Science and Technology 114 (10), 1148-1153, 2012
472012
Deracemisation of aromatic β-hydroxy esters using immobilised whole cells of Candida parapsilosis ATCC 7330 and determination of absolute configuration by 1H NMR
SK Padhi, A Chadha
Tetrahedron: Asymmetry 16 (16), 2790-2798, 2005
422005
Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions
A Chadha, S Venkataraman, R Preetha, SK Padhi
Bioorganic chemistry 68, 187-213, 2016
352016
Uncovering divergent evolution of α/β-hydrolases: a surprising residue substitution needed to convert Hevea brasiliensis hydroxynitrile lyase into an esterase
DM Nedrud, H Lin, G Lopez, SK Padhi, GA Legatt, RJ Kazlauskas
Chemical science 5 (11), 4265-4277, 2014
262014
Reductions of cyclic β-keto esters by individual Saccharomyces cerevisiae dehydrogenases and a chemo-enzymatic route to (1R, 2S)-2-methyl-1-cyclohexanol
SK Padhi, IA Kaluzna, D Buisson, R Azerad, JD Stewart
Tetrahedron: Asymmetry 18 (18), 2133-2138, 2007
252007
Modern approaches to discovering new hydroxynitrile lyases for biocatalysis
SK Padhi
ChemBioChem 18 (2), 152-160, 2017
172017
Sodium borohydride reduction and selective transesterification of β-keto esters in a one-pot reaction under mild conditions
SK Padhi, A Chadha
Synlett 2003 (05), 0639-0642, 2003
172003
Biocatalytic approaches for enantio and diastereoselective synthesis of chiral β-nitroalcohols
DHS Rao, A Chatterjee, SK Padhi
Organic & Biomolecular Chemistry 19 (2), 322-337, 2021
152021
Immobilized Baliospermum montanum hydroxynitrile lyase catalyzed synthesis of chiral cyanohydrins
N Jangir, SK Padhi
Bioorganic Chemistry 84, 32-40, 2019
132019
Production of (S)‐β‐Nitro Alcohols by Enantioselective C−C Bond Cleavage with an R‐Selective Hydroxynitrile Lyase
DHS Rao, SK Padhi
ChemBioChem 20 (3), 371-378, 2019
112019
Immobilized Arabidopsis thaliana Hydroxynitrile Lyase-Catalyzed Retro-Henry Reaction in the Synthesis of (S)-β-Nitroalcohols
DHS Rao, K Shivani, SK Padhi
Applied Biochemistry and Biotechnology 193 (2), 560-576, 2021
102021
An ultrasensitive fluorescence assay for the detection of halides and enzymatic dehalogenation
AS Aslan‐Üzel, A Beier, D Kovář, C Cziegler, SK Padhi, ED Schuiten, ...
ChemCatChem 12 (7), 2032-2039, 2020
92020
Lipase‐catalyzed transesterification to remove saturated MAG from biodiesel
SK Padhi, M Haas, UT Bornscheuer
European Journal of Lipid Science and Technology 114 (8), 875-879, 2012
92012
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