| Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs SS Carroll, JE Tomassini, M Bosserman, K Getty, MW Stahlhut, AB Eldrup, ... Journal of Biological Chemistry 278 (14), 11979-11984, 2003 | 441 | 2003 |
| Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase SS Carroll, DB Olsen, M MacCoss, B Bhat, PD Cook, AB Eldrup, ... US Patent 7,105,499, 2006 | 293 | 2006 |
| Tourism and development in the Global South: The issues F Brown, D Hall Third World Quarterly 29 (5), 839-849, 2008 | 216 | 2008 |
| Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases Z Chen, Y Li, E Chen, DL Hall, PL Darke, C Culberson, JA Shafer, LC Kuo Journal of Biological Chemistry 269 (42), 26344-26348, 1994 | 213 | 1994 |
| Tourism in peripheral areas: Case studies F Brown, DD Hall, DR Hall Channel View Publications, 2000 | 196 | 2000 |
| Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates D Hall, G Ybazeta, G Destro-Bisol, ML Petzl-Erler, A Di Rienzo Pharmacogenetics and Genomics 9 (5), 591-606, 1999 | 175 | 1999 |
| Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40 J Lu, N Byrne, J Wang, G Bricogne, FK Brown, HR Chobanian, SL Colletti, ... Nature structural & molecular biology 24 (7), 570-577, 2017 | 166 | 2017 |
| Three-dimensional Structure of a Mutant HIV-1 Protease Displaying Cross-resistance to All Protease Inhibitors in Clinical Trials (∗) Z Chen, Y Li, HB Schock, D Hall, E Chen, LC Kuo Journal of Biological Chemistry 270 (37), 21433-21436, 1995 | 145 | 1995 |
| Active Human Cytomegalovirus Protease Is a Dimer (∗) PL Darke, JL Cole, L Waxman, DL Hall, MK Sardana, LC Kuo Journal of Biological Chemistry 271 (13), 7445-7449, 1996 | 116 | 1996 |
| Insights into activity and inhibition from the crystal structure of human O-GlcNAcase NL Elsen, SB Patel, RE Ford, DL Hall, F Hess, H Kandula, M Kornienko, ... Nature chemical biology 13 (6), 613-615, 2017 | 93 | 2017 |
| Dissociation and association of the HIV-1 protease dimer subunits: equilibria and rates PL Darke, DL Hall, SP Jordan, JA Zugay, JA Shafer, LC Kuo Biochemistry 33 (1), 98-105, 1994 | 86 | 1994 |
| Crystal structure of the apo, unactivated insulin-like growth factor-1 receptor kinase: implication for inhibitor specificity S Munshi, M Kornienko, DL Hall, JC Reid, L Waxman, SM Stirdivant, ... Journal of Biological Chemistry 277 (41), 38797-38802, 2002 | 84 | 2002 |
| Only a small fraction of purified hepatitis C RNA-dependent RNA polymerase is catalytically competent: implications for viral replication and in vitro assays SS Carroll, V Sardana, Z Yang, AR Jacobs, C Mizenko, D Hall, L Hill, ... Biochemistry 39 (28), 8243-8249, 2000 | 81 | 2000 |
| Structure of apo, unactivated insulin-like growth factor-1 receptor kinase at 1.5 Å resolution S Munshi, DL Hall, M Kornienko, PL Darke, LC Kuo Acta Crystallographica Section D: Biological Crystallography 59 (10), 1725-1730, 2003 | 80 | 2003 |
| Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation C Hong, NJ Byrne, B Zamlynny, S Tummala, L Xiao, JM Shipman, ... Nature communications 12 (1), 815, 2021 | 79 | 2021 |
| Activation of the Herpes Simplex Virus Type 1 Protease (∗) DL Hall, PL Darke Journal of Biological Chemistry 270 (39), 22697-22700, 1995 | 77 | 1995 |
| Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase SM Soisson, SB Patel, PD Abeywickrema, NJ Byrne, RE Diehl, DL Hall, ... BMC structural biology 10, 1-8, 2010 | 64 | 2010 |
| Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation T Sunami, N Byrne, RE Diehl, K Funabashi, DL Hall, M Ikuta, SB Patel, ... Journal of Biological Chemistry 285 (7), 4587-4594, 2010 | 62 | 2010 |
| Purification of active herpes simplex virus-1 protease expressed in Escherichia coli. PL Darke, E Chen, DL Hall, MK Sardana, CA Veloski, RL LaFemina, ... Journal of Biological Chemistry 269 (29), 18708-18711, 1994 | 43 | 1994 |
| Structural basis for selective small molecule kinase inhibition of activated c-Met KW Rickert, SB Patel, TJ Allison, NJ Byrne, PL Darke, RE Ford, DJ Guerin, ... Journal of Biological Chemistry 286 (13), 11218-11225, 2011 | 42 | 2011 |
