Alex Ruthenburg
Alex Ruthenburg
Molecular Genetics and Cell Biology, University of Chicago
Verified email at - Homepage
Cited by
Cited by
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
SD Taverna, H Li, AJ Ruthenburg, CD Allis, DJ Patel
Nature structural & molecular biology 14 (11), 1025-1040, 2007
Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark
AJ Ruthenburg, CD Allis, J Wysocka
Molecular cell 25 (1), 15-30, 2007
Multivalent engagement of chromatin modifications by linked binding modules
AJ Ruthenburg, H Li, DJ Patel, C David Allis
Nature reviews Molecular cell biology 8 (12), 983-994, 2007
Regulation of MLL1 H3K4 methyltransferase activity by its core components
Y Dou, TA Milne, AJ Ruthenburg, S Lee, JW Lee, GL Verdine, CD Allis, ...
Nature structural & molecular biology 13 (8), 713-719, 2006
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions
AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ...
Cell 145 (5), 692-706, 2011
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
AJ Ruthenburg, W Wang, DM Graybosch, H Li, CD Allis, DJ Patel, ...
Nature structural & molecular biology 13 (8), 704-712, 2006
Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase
H Wei, AJ Ruthenburg, SK Bechis, GL Verdine
Journal of Biological Chemistry 280 (44), 37041-37047, 2005
Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis
TA Milne, J Kim, GG Wang, SC Stadler, V Basrur, SJ Whitcomb, Z Wang, ...
Molecular cell 38 (6), 853-863, 2010
Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA
HC Losey, AJ Ruthenburg, GL Verdine
Nature structural & molecular biology 13 (2), 153-159, 2006
Nuclear fractionation reveals thousands of chromatin-tethered noncoding RNAs adjacent to active genes
MS Werner, AJ Ruthenburg
Cell reports 12 (7), 1089-1098, 2015
An interactive database for the assessment of histone antibody specificity
SB Rothbart, BM Dickson, JR Raab, AT Grzybowski, K Krajewski, AH Guo, ...
Molecular cell 59 (3), 502-511, 2015
A superhelical spiral in the Escherichia coli DNA gyrase A C-terminal domain imparts unidirectional supercoiling bias
AJ Ruthenburg, DM Graybosch, JC Huetsch, GL Verdine
Journal of Biological Chemistry 280 (28), 26177-26184, 2005
Examining the roles of H3K4 methylation states with systematically characterized antibodies
RN Shah, AT Grzybowski, EM Cornett, AL Johnstone, BM Dickson, ...
Molecular cell 72 (1), 162-177. e7, 2018
Calibrating ChIP-Seq with nucleosomal internal standards to measure histone modification density genome wide
AT Grzybowski, Z Chen, AJ Ruthenburg
Molecular cell 58 (5), 886-899, 2015
Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription
MS Werner, MA Sullivan, RN Shah, RD Nadadur, AT Grzybowski, V Galat, ...
Nature structural & molecular biology 24 (7), 596-603, 2017
Recombinant antibodies to histone post-translational modifications
T Hattori, JM Taft, KM Swist, H Luo, H Witt, M Slattery, A Koide, ...
Nature methods 10 (10), 992-995, 2013
A mutation in histone H2B represents a new class of oncogenic driver
RL Bennett, A Bele, EC Small, CM Will, B Nabet, JA Oyer, X Huang, ...
Cancer discovery 9 (10), 1438-1451, 2019
Targeting the MTF2–MDM2 axis sensitizes refractory acute myeloid leukemia to chemotherapy
HB Maganti, H Jrade, C Cafariello, JL Manias Rothberg, CJ Porter, ...
Cancer discovery 8 (11), 1376-1389, 2018
Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation
T Hattori, D Lai, IS Dementieva, SP Montaņo, K Kurosawa, Y Zheng, ...
Proceedings of the National Academy of Sciences 113 (8), 2092-2097, 2016
Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm
XH Yang, RD Nadadur, CRE Hilvering, V Bianchi, M Werner, SR Mazurek, ...
Elife 6, e31683, 2017
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