| GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas RG Majzner, S Ramakrishna, KW Yeom, S Patel, H Chinnasamy, ... Nature 603 (7903), 934-941, 2022 | 408 | 2022 |
| Single-cell RNA-seq reveals cellular hierarchies and impaired developmental trajectories in pediatric ependymoma J Gojo, B Englinger, L Jiang, JM Hübner, MKL Shaw, OA Hack, ... Cancer cell 38 (1), 44-59. e9, 2020 | 115 | 2020 |
| Latent effects of Hsp90 mutants revealed at reduced expression levels L Jiang, P Mishra, RT Hietpas, KB Zeldovich, DNA Bolon PLoS genetics 9 (6), e1003600, 2013 | 100 | 2013 |
| Fitness analyses of all possible point mutations for regions of genes in yeast R Hietpas, B Roscoe, L Jiang, DNA Bolon Nature protocols 7 (7), 1382-1396, 2012 | 97 | 2012 |
| Viewing protein fitness landscapes through a next-gen lens JI Boucher, P Cote, J Flynn, L Jiang, A Laban, P Mishra, BP Roscoe, ... Genetics 198 (2), 461-471, 2014 | 59 | 2014 |
| The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location I Liu, L Jiang, ER Samuelsson, S Marco Salas, A Beck, OA Hack, D Jeong, ... Nature Genetics 54 (12), 1881-1894, 2022 | 55 | 2022 |
| A balance between inhibitor binding and substrate processing confers influenza drug resistance L Jiang, P Liu, C Bank, N Renzette, K Prachanronarong, LS Yilmaz, ... Journal of molecular biology 428 (3), 538-553, 2016 | 40 | 2016 |
| Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth CH Man, FE Mercier, N Liu, W Dong, G Stephanopoulos, L Jiang, Y Jung, ... Blood, The Journal of the American Society of Hematology 139 (4), 502-522, 2022 | 30 | 2022 |
| Saturation mutagenesis of the HIV-1 envelope CD4 binding loop reveals residues controlling distinct trimer conformations M Duenas-Decamp, L Jiang, D Bolon, PR Clapham PLoS pathogens 12 (11), e1005988, 2016 | 29 | 2016 |
| Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ... Science translational medicine 13 (614), eabc0497, 2021 | 28 | 2021 |
| Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ... Cancer discovery 13 (11), 2370-2393, 2023 | 26 | 2023 |
| BAF complex maintains glioma stem cells in pediatric H3K27M glioma E Panditharatna, JG Marques, T Wang, MC Trissal, I Liu, L Jiang, A Beck, ... Cancer discovery 12 (12), 2880-2905, 2022 | 23 | 2022 |
| Targeting fibroblast growth factor receptors to combat aggressive ependymoma D Lötsch, D Kirchhofer, B Englinger, L Jiang, K Okonechnikov, D Senfter, ... Acta neuropathologica 142 (2), 339-360, 2021 | 16 | 2021 |
| Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways M Pun, D Pratt, PR Nano, PK Joshi, L Jiang, B Englinger, A Rao, M Cieslik, ... Acta Neuropathologica Communications 11 (1), 25, 2023 | 12 | 2023 |
| TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory I Ausejo-Mauleon, S Labiano, D de la Nava, V Laspidea, M Zalacain, ... Cancer cell 41 (11), 1911-1926. e8, 2023 | 11 | 2023 |
| Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma D Messinger, MK Harris, JR Cummings, C Thomas, T Yang, SR Sweha, ... Neuro-oncology 25 (1), 54-67, 2023 | 7 | 2023 |
| GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas., 2022, 603 RG Majzner, S Ramakrishna, KW Yeom, S Patel, H Chinnasamy, ... DOI: https://doi. org/10.1038/s41586-022-04489-4, 934-941, 0 | 6 | |
| Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymoma T de Almeida Magalhães, G Alencastro Veiga Cruzeiro, ... Neuro-oncology 25 (1), 185-198, 2023 | 3 | 2023 |
| MODIFYING THE TUMOR MICROENVIRONMENT WITH A TIM-3 MONOCLONAL ANTIBODY AS A THERAPEUTIC STRATEGY FOR DIPGS I Ausejo-Mauleon, S Labiano, D De la Nava, M Garcia-Moure, V Laspidea, ... NEURO-ONCOLOGY 24, 22-23, 2022 | 1 | 2022 |
| TMET-02. CLINICAL EFFICACY OF ONC201 IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMAS IS DRIVEN BY DISRUPTION OF INTEGRATED METABOLIC AND EPIGENETIC PATHWAYS S Venneti, AR Kawakibi, S Ji, S Waszak, S Sweha, M Mota, M Pun, ... Neuro-Oncology 25 (Supplement_5), v272-v272, 2023 | | 2023 |
