Kinase-targeted cancer therapies: progress, challenges and future directions KS Bhullar, NO Lagarón, EM McGowan, I Parmar, A Jha, BP Hubbard, ... Molecular cancer 17, 1-20, 2018 | 1095 | 2018 |
Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle PA Mote, RL Balleine, EM McGowan, CL Clarke The Journal of Clinical Endocrinology & Metabolism 84 (8), 2963-2971, 1999 | 384 | 1999 |
The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle V Boonyaratanakornkit, E McGowan, L Sherman, MA Mancini, BJ Cheskis, ... Molecular Endocrinology 21 (2), 359-375, 2007 | 276 | 2007 |
PTEN/PTENP1:‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy N Haddadi, Y Lin, G Travis, AM Simpson, NT Nassif, EM McGowan Molecular cancer 17, 1-14, 2018 | 252 | 2018 |
Nattokinase: a promising alternative in prevention and treatment of cardiovascular diseases H Chen, EM McGowan, N Ren, S Lal, N Nassif, F Shad-Kaneez, X Qu, ... Biomarker insights 13, 1177271918785130, 2018 | 159 | 2018 |
Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma PA Mote, RL Balleine, EM McGowan, CL Clarke Human Reproduction 15 (suppl_3), 48-56, 2000 | 156 | 2000 |
Effect of overexpression of progesterone receptor A on endogenous progestin-sensitive endpoints in breast cancer cells EM McGowan, CL Clarke Molecular Endocrinology 13 (10), 1657-1671, 1999 | 137 | 1999 |
Preferential Stimulation of Human Progesterone Receptor B Expression by Estrogen in T-47D Human Breast Cancer Cells (∗) JD Graham, SD Roman, E McGowan, RL Sutherland, CL Clarke Journal of Biological Chemistry 270 (51), 30693-30700, 1995 | 117 | 1995 |
PD-1 disrupted CAR-T cells in the treatment of solid tumors: Promises and challenges E McGowan, Q Lin, G Ma, H Yin, S Chen, Y Lin Biomedicine & Pharmacotherapy 121, 109625, 2020 | 116 | 2020 |
Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget D Hatoum, N Haddadi, Y Lin, NT Nassif, EM McGowan Oncotarget 8 (22), 36898, 2017 | 98 | 2017 |
Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay EM McGowan, N Alling, EA Jackson, D Yagoub, NK Haass, JD Allen, ... PloS one 6 (6), e20623, 2011 | 96 | 2011 |
Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires sphingosine kinase activity JL Martin, MZ Lin, EM McGowan, RC Baxter Journal of biological chemistry 284 (38), 25542-25552, 2009 | 87 | 2009 |
Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: therapeutic potential for ovarian cancer N Zhang, ZM Wu, E McGowan, J Shi, ZB Hong, CW Ding, P Xia, W Di Cancer science 100 (12), 2459-2464, 2009 | 81 | 2009 |
The roles of p53 in mitochondrial dynamics and cancer metabolism: the pendulum between survival and death in breast cancer? DE Moulder, D Hatoum, E Tay, Y Lin, EM McGowan Cancers 10 (6), 189, 2018 | 80 | 2018 |
Recent advances in the use of metformin: can treating diabetes prevent breast cancer? D Hatoum, EM McGowan BioMed research international 2015, 2015 | 79 | 2015 |
Effect of progesterone receptor a predominance on breast cancer cell migration into bone marrow fibroblasts EM McGowan, S Saad, LJ Bendall, KF Bradstock, CL Clarke Breast cancer research and treatment 83, 211-220, 2004 | 55 | 2004 |
Targeting the SphK-S1P-SIPR pathway as a potential therapeutic approach for COVID-19 EM McGowan, N Haddadi, NT Nassif, Y Lin International Journal of Molecular Sciences 21 (19), 7189, 2020 | 48 | 2020 |
Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor EM McGowan, AJ Russell, V Boonyaratanakornkit, DN Saunders, ... Cancer research 67 (18), 8942-8951, 2007 | 47 | 2007 |
Extranuclear signaling by sex steroid receptors and clinical implications in breast cancer V Boonyaratanakornkit, N Hamilton, DC Márquez-Garbán, P Pateetin, ... Molecular and cellular endocrinology 466, 51-72, 2018 | 42 | 2018 |
Saikosaponin-d suppresses COX2 through p-STAT3/C/EBPβ signaling pathway in liver cancer: a novel mechanism of action M Ren, E McGowan, Y Li, X Zhu, X Lu, Z Zhu, Y Lin, S He Frontiers in Pharmacology 10, 623, 2019 | 40 | 2019 |