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Jan Stursa
Jan Stursa
Institute of Biotechnology of the Czech Academy of Sciences
Verifierad e-postadress på ibt.cas.cz
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Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II
LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ...
Journal of Biological Chemistry 286 (5), 3717-3728, 2011
2332011
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy
LF Dong, VJA Jameson, D Tilly, L Prochazka, J Rohlena, K Valis, J Truksa, ...
Free Radical Biology and Medicine 50 (11), 1546-1555, 2011
1242011
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer
K Rohlenova, K Sachaphibulkij, J Stursa, A Bezawork-Geleta, J Blecha, ...
Antioxidants & redox signaling 26 (2), 84-103, 2017
1112017
Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism
E Cuyàs, S Fernández-Arroyo, S Verdura, RÁF García, J Stursa, L Werner, ...
Oncogene 37 (7), 963-970, 2018
1042018
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2
S Hubackova, E Davidova, K Rohlenova, J Stursa, L Werner, L Andera, ...
Cell Death & Differentiation 26 (2), 276-290, 2019
902019
Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner
B Yan, M Stantic, R Zobalova, A Bezawork-Geleta, M Stapelberg, J Stursa, ...
BMC cancer 15, 1-12, 2015
792015
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX
E Cuyas, S Verdura, L Llorach‐Pares, S Fernández‐Arroyo, ...
Aging cell 17 (4), e12772, 2018
702018
Mitochondrial targeting of metformin enhances its activity against pancreatic cancer
S Boukalova, J Stursa, L Werner, Z Ezrova, J Cerny, A Bezawork-Geleta, ...
Molecular cancer therapeutics 15 (12), 2875-2886, 2016
692016
Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing
J Rohlena, LF Dong, K Kluckova, R Zobalova, J Goodwin, D Tilly, J Stursa, ...
Antioxidants & redox signaling 15 (12), 2923-2935, 2011
682011
Targeting mitochondrial iron metabolism suppresses tumor growth and metastasis by inducing mitochondrial dysfunction and mitophagy
C Sandoval-Acuna, N Torrealba, V Tomkova, SB Jadhav, K Blazkova, ...
Cancer Research 81 (9), 2289-2303, 2021
622021
Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis
J Truksa, LF Dong, J Rohlena, J Stursa, M Vondrusova, J Goodwin, ...
Antioxidants & redox signaling 22 (11), 883-900, 2015
502015
Mitochondrial targeting overcomes ABCA1-dependent resistance of lung carcinoma to α-tocopheryl succinate
L Prochazka, S Koudelka, LF Dong, J Stursa, J Goodwin, J Neca, J Slavik, ...
Apoptosis 18, 286-299, 2013
472013
Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy
J Kovarova, M Bajzikova, M Vondrusova, J Stursa, J Goodwin, M Nguyen, ...
Redox Report 19 (1), 16-25, 2014
422014
Indoleamine-2, 3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans
M Stapelberg, R Zobalova, MN Nguyen, T Walker, M Stantic, J Goodwin, ...
Free Radical Biology and Medicine 67, 41-50, 2014
372014
Microwave-Assisted Alkylation of [CB11H12] and Related Anions
M Valášek, J Štursa, R Pohl, J Michl
Inorganic chemistry 49 (22), 10247-10254, 2010
312010
Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents
EA Pasdar, M Smits, M Stapelberg, M Bajzikova, M Stantic, J Goodwin, ...
PLoS One 10 (5), e0119549, 2015
302015
Measured and Calculated Oxidation Potentials of 1-X-12-Y-CB11Me10 Anions
A Wahab, B Stepp, C Douvris, M Valasek, J Stursa, J Klı́ma, MC Piqueras, ...
Inorganic Chemistry 51 (9), 5128-5137, 2012
272012
SMAD4 loss limits the vulnerability of pancreatic cancer cells to complex I inhibition via promotion of mitophagy
Z Ezrova, Z Nahacka, J Stursa, L Werner, E Vlcak, P Kralova Viziova, ...
Oncogene 40 (14), 2539-2552, 2021
242021
Lithium Salts of [1,12-Dialkyl-CB11Me10] Anions
M Valášek, J Štursa, R Pohl, J Michl
Inorganic chemistry 49 (22), 10255-10263, 2010
242010
Structural re-arrangement and peroxidase activation of cytochrome c by anionic analogues of vitamin E, tocopherol succinate and tocopherol phosphate
N Yanamala, AA Kapralov, M Djukic, J Peterson, G Mao, ...
Journal of Biological Chemistry 289 (47), 32488-32498, 2014
212014
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Artiklar 1–20