Follow
J. Nicholas (Nick) Cochran, Ph.D.
J. Nicholas (Nick) Cochran, Ph.D.
Verified email at hudsonalpha.org - Homepage
Title
Cited by
Cited by
Year
Genomic diagnosis for children with intellectual disability and/or developmental delay
KM Bowling, ML Thompson, MD Amaral, CR Finnila, SM Hiatt, KL Engel, ...
Genome medicine 9, 1-11, 2017
2242017
Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
ME Seward, E Swanson, A Norambuena, A Reimann, JN Cochran, R Li, ...
Journal of cell science 126 (5), 1278-1286, 2013
1932013
The dendritic hypothesis for Alzheimer's disease pathophysiology
JN Cochran, AM Hall, ED Roberson
Brain research bulletin 103, 18-28, 2014
1272014
Aberrant inclusion of a poison exon causes Dravet syndrome and related SCN1A-associated genetic epilepsies
GL Carvill, KL Engel, A Ramamurthy, JN Cochran, J Roovers, ...
The American Journal of Human Genetics 103 (6), 1022-1029, 2018
922018
Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy
AM Bradbury, JN Cochran, VJ McCurdy, AK Johnson, BL Brunson, ...
Molecular Therapy 21 (7), 1306-1315, 2013
912013
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ...
Nature genetics 54 (12), 1786-1794, 2022
83*2022
The multi-partner consortium to expand dementia research in Latin America (ReDLat): driving multicentric research and implementation science
A Ibanez, JS Yokoyama, KL Possin, D Matallana, F Lopera, R Nitrini, ...
Frontiers in neurology 12, 631722, 2021
652021
De novo mutations in MED13, a component of the Mediator complex, are associated with a novel neurodevelopmental disorder
L Snijders Blok, SM Hiatt, KM Bowling, JW Prokop, KL Engel, JN Cochran, ...
Human genetics 137, 375-388, 2018
642018
Non-coding and loss-of-function coding variants in TET2 are associated with multiple neurodegenerative diseases
JN Cochran, EG Geier, LW Bonham, JS Newberry, MD Amaral, ...
The American Journal of Human Genetics 106 (5), 632-645, 2020
592020
The Alzheimer's disease risk factor CD2AP maintains blood–brain barrier integrity
JN Cochran, T Rush, SC Buckingham, ED Roberson
Human molecular genetics 24 (23), 6667-6674, 2015
472015
Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability
Y Voskobiynyk, JR Roth, JN Cochran, T Rush, NVN Carullo, JS Mesina, ...
Elife 9, e57354, 2020
432020
Systematic reanalysis of genomic data improves quality of variant interpretation
SM Hiatt, MD Amaral, KM Bowling, CR Finnila, ML Thompson, DE Gray, ...
Clinical genetics 94 (1), 174-178, 2018
412018
Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)
LR Aguilar, J Acosta-Uribe, MM Giraldo, S Moreno, A Baena, D Alzate, ...
Alzheimer's & Dementia 15 (5), 709-719, 2019
332019
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia
EG Geier, M Bourdenx, NJ Storm, JN Cochran, DW Sirkis, JH Hwang, ...
Acta neuropathologica 137, 71-88, 2019
302019
Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles
JN Cochran, EC McKinley, M Cochran, MD Amaral, BA Moyers, ...
Molecular Case Studies 5 (6), a003491, 2019
292019
Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements
LFR Ashlyn G. Anderson, Brianne B. Rogers , Jacob M. Loupe, Ivan Rodriguez ...
Cell Genomics, 2023
252023
A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity
T Rush, JR Roth, SJ Thompson, AR Aldaher, JN Cochran, ED Roberson
Neurobiology of disease 134, 104668, 2020
252020
AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of tau–fyn SH3 interaction inhibitors for Alzheimer disease
JN Cochran, PV Diggs, NM Nebane, L Rasmussen, EL White, R Bostwick, ...
Journal of biomolecular screening 19 (10), 1338-1349, 2014
242014
Biomarkers for dementia in Latin American countries: Gaps and opportunities
MA Parra, P Orellana, T Leon, CG Victoria, F Henriquez, R Gomez, ...
Alzheimer's & Dementia 19 (2), 721-735, 2023
212023
A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects
J Acosta-Uribe, D Aguillón, JN Cochran, M Giraldo, L Madrigal, ...
Genome Medicine 14 (1), 27, 2022
202022
The system can't perform the operation now. Try again later.
Articles 1–20