Endothelial-to-mesenchymal transition drives atherosclerosis progression PY Chen, L Qin, N Baeyens, G Li, T Afolabi, M Budatha, G Tellides, ... The Journal of clinical investigation 125 (12), 4514-4528, 2015 | 485 | 2015 |
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ... Nature metabolism 1 (9), 912-926, 2019 | 206 | 2019 |
Smooth muscle cell reprogramming in aortic aneurysms PY Chen, L Qin, G Li, J Malagon-Lopez, Z Wang, S Bergaya, S Gujja, ... Cell stem cell 26 (4), 542-557. e11, 2020 | 145 | 2020 |
Caveolin-1 regulates atherogenesis by attenuating low-density lipoprotein transcytosis and vascular inflammation independently of endothelial nitric oxide synthase activation CM Ramírez, X Zhang, C Bandyopadhyay, N Rotllan, MG Sugiyama, ... Circulation 140 (3), 225-239, 2019 | 120 | 2019 |
Tissue-engineered vascular grafts with advanced mechanical strength from human iPSCs J Luo, L Qin, L Zhao, L Gui, MW Ellis, Y Huang, MH Kural, JA Clark, S Ono, ... Cell Stem Cell 26 (2), 251-261. e8, 2020 | 111 | 2020 |
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ... Nature Communications 8 (1), 191, 2017 | 89 | 2017 |
Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation PY Chen, L Qin, G Li, G Tellides, M Simons Scientific reports 6 (1), 33407, 2016 | 82 | 2016 |
Smooth muscle FGF/TGF β cross talk regulates atherosclerosis progression PY Chen, L Qin, G Li, G Tellides, M Simons EMBO molecular medicine 8 (7), 712-728, 2016 | 82 | 2016 |
Pharmacologically improved contractility protects against aortic dissection in mice with disrupted transforming growth factor-β signaling despite compromised extracellular … J Ferruzzi, SI Murtada, G Li, Y Jiao, S Uman, MYL Ting, G Tellides, ... Arteriosclerosis, thrombosis, and vascular biology 36 (5), 919-927, 2016 | 75 | 2016 |
Chronic mTOR activation induces a degradative smooth muscle cell phenotype G Li, M Wang, AW Caulk, NA Cilfone, S Gujja, L Qin, PY Chen, Z Chen, ... The Journal of clinical investigation 130 (3), 1233-1251, 2020 | 73 | 2020 |
Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes D Jane-wit, YV Surovtseva, L Qin, G Li, R Liu, P Clark, TD Manes, C Wang, ... Proceedings of the National Academy of Sciences 112 (31), 9686-9691, 2015 | 68 | 2015 |
Complement membrane attack complexes assemble NLRP3 inflammasomes triggering IL-1 activation of IFN-γ–primed human endothelium CB Xie, L Qin, G Li, C Fang, NC Kirkiles-Smith, G Tellides, JS Pober, ... Circulation research 124 (12), 1747-1759, 2019 | 63 | 2019 |
Improving in vivo outcomes of decellularized vascular grafts via incorporation of a novel extracellular matrix NJ Kristofik, L Qin, NE Calabro, S Dimitrievska, G Li, G Tellides, ... Biomaterials 141, 63-73, 2017 | 60 | 2017 |
Deficient circumferential growth is the primary determinant of aortic obstruction attributable to partial elastin deficiency Y Jiao, G Li, A Korneva, AW Caulk, L Qin, MR Bersi, Q Li, W Li, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 930-941, 2017 | 52 | 2017 |
Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion G Li, L Qin, L Wang, X Li, AW Caulk, J Zhang, PY Chen, S Xin American Journal of Physiology-Heart and Circulatory Physiology 312 (6 …, 2017 | 44 | 2017 |
Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering J Luo, L Qin, MH Kural, J Schwan, X Li, O Bartulos, X Cong, Y Ren, L Gui, ... Biomaterials 147, 116-132, 2017 | 40 | 2017 |
Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts S Dimitrievska, J Wang, T Lin, A Weyers, H Bai, L Qin, G Li, C Cai, ... Advanced Functional Materials 30 (23), 1908963, 2020 | 39 | 2020 |
Endothelial cell–derived interleukin-18 released during ischemia reperfusion injury selectively expands t peripheral helper cells to promote alloantibody production L Liu, C Fang, W Fu, B Jiang, G Li, L Qin, J Rosenbluth, G Gong, CB Xie, ... Circulation 141 (6), 464-478, 2020 | 34 | 2020 |
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes C Fang, TD Manes, L Liu, K Liu, L Qin, G Li, Z Tobiasova, ... Nature communications 10 (1), 2247, 2019 | 32 | 2019 |
mTOR (mechanistic target of rapamycin) inhibition decreases mechanosignaling, collagen accumulation, and stiffening of the thoracic aorta in elastin-deficient mice Y Jiao, G Li, Q Li, R Ali, L Qin, W Li, Y Qyang, DM Greif, A Geirsson, ... Arteriosclerosis, Thrombosis, and Vascular Biology 37 (9), 1657-1666, 2017 | 31 | 2017 |