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Tae Hun Kim
Tae Hun Kim
Assistant Professor, Department of Biochemistry, Case Western Reserve University
Verifierad e-postadress på case.edu - Startsida
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Structural insights into the dynamic process of β 2-adrenergic receptor signaling
A Manglik, TH Kim, M Masureel, C Altenbach, Z Yang, D Hilger, MT Lerch, ...
Cell 161 (5), 1101-1111, 2015
6692015
Pi-Pi contacts are an overlooked protein feature relevant to phase separation
RMC Vernon, PA Chong, B Tsang, TH Kim, A Bah, P Farber, H Lin, ...
Elife 7, e31486, 2018
6072018
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
3162016
Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
TH Kim, B Tsang, RM Vernon, N Sonenberg, LE Kay, JD Forman-Kay
Science 365 (6455), 825-829, 2019
2522019
The role of ligands on the equilibria between functional states of a G protein-coupled receptor
TH Kim, KY Chung, A Manglik, AL Hansen, RO Dror, TJ Mildorf, DE Shaw, ...
Journal of the American Chemical Society 135 (25), 9465-9474, 2013
1982013
The role of dimer asymmetry and protomer dynamics in enzyme catalysis
TH Kim, P Mehrabi, Z Ren, A Sljoka, C Ing, A Bezginov, L Ye, R Pomès, ...
Science 355 (6322), 2017
1642017
Role of detergents in conformational exchange of a G protein-coupled receptor
KY Chung, TH Kim, A Manglik, R Alvares, BK Kobilka, RS Prosser
Journal of Biological Chemistry 287 (43), 36305-36311, 2012
1182012
NMR experiments for studies of dilute and condensed protein phases: Application to the phase-separating protein CAPRIN1
LE Wong, TH Kim, DR Muhandiram, JD Forman-Kay, LE Kay
Journal of the American Chemical Society, 2020
622020
Synergy of cAMP and calcium signaling pathways in CFTR regulation
Z Bozoky, S Ahmadi, T Milman, TH Kim, K Du, M Di Paola, S Pasyk, ...
Proceedings of the National Academy of Sciences 114 (11), E2086-E2095, 2017
622017
Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
TH Kim, BJ Payliss, ML Nosella, ITW Lee, Y Toyama, JD Forman-Kay, ...
Proceedings of the National Academy of Sciences 118 (23), 2021
522021
Substrate-based Allosteric Regulation of a Homodimeric Enzyme
P Mehrabi, C Di Pietrantonio, TH Kim, A Sljoka, K Taverner, C Ing, ...
Journal of the American Chemical Society 141 (29), 11540−11556, 2019
302019
Correlating histone acetylation with nucleosome core particle dynamics and function
TH Kim, ML Nosella, N Bolik-Coulon, RW Harkness, SK Huang, LE Kay
Proceedings of the National Academy of Sciences 120 (15), e2301063120, 2023
112023
Confronting the Invisible: Assignment of Protein 1HN Chemical Shifts in Cases of Extreme Broadening
LE Wong, TH Kim, E Rennella, P Vallurupalli, LE Kay
The Journal of Physical Chemistry Letters 11 (9), 3384-3389, 2020
82020
Nuts and Bolts of CF3 and CH3 NMR Toward the Understanding of Conformational Exchange of GPCRs
RS Prosser, TH Kim
G Protein-Coupled Receptors in Drug Discovery, 39-51, 2015
82015
Poly (ADP-ribosyl) ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates
ML Nosella, TH Kim, SK Huang, RW Harkness, M Goncalves, A Pan, ...
Molecular Cell, 2024
22024
Functional Dynamics of the β2-Adrenergic Receptor and Fluoroacetate Dehalogenase by 19F NMR
TH Kim
2016
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Artiklar 1–16