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Philip Alexander Heine
Philip Alexander Heine
Verified email at tu-bs.de
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Year
A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations
F Bertoglio, V Fühner, M Ruschig, PA Heine, L Abassi, T Klünemann, ...
Cell reports 36 (4), 2021
88*2021
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant
M Schubert, F Bertoglio, S Steinke, PA Heine, MA Ynga-Durand, H Maass, ...
BMC medicine 20 (1), 102, 2022
862022
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
F Bertoglio, D Meier, N Langreder, S Steinke, U Rand, L Simonelli, ...
Nature communications 12 (1), 1577, 2021
822021
Developing recombinant antibodies by phage display against infectious diseases and toxins for diagnostics and therapy
KDR Roth, EV Wenzel, M Ruschig, S Steinke, N Langreder, PA Heine, ...
Frontiers in cellular and infection microbiology 11, 697876, 2021
532021
Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile
V Fühner, PA Heine, S Helmsing, S Goy, J Heidepriem, FF Loeffler, ...
Frontiers in microbiology 9, 2908, 2018
202018
Epitope mapping via phage display from single-gene libraries
V Fühner, PA Heine, KJC Zilkens, D Meier, KDR Roth, GMSG Moreira, ...
Human Monoclonal Antibodies: Methods and Protocols, 353-375, 2019
102019
ORFeome phage display reveals a major immunogenic epitope on the S2 subdomain of SARS-CoV-2 spike protein
R Ballmann, SK Hotop, F Bertoglio, S Steinke, PA Heine, MZ Chaudhry, ...
Viruses 14 (6), 1326, 2022
82022
Baculovirus-Free SARS-CoV-2 virus-like particle production in insect cells for rapid neutralization assessment
M Jaron, M Lehky, M Zarà, CN Zaydowicz, A Lak, R Ballmann, PA Heine, ...
Viruses 14 (10), 2087, 2022
62022
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface. Nat Commun 12: 1577
F Bertoglio, D Meier, N Langreder, S Steinke, U Rand, L Simonelli, ...
52021
Plant defense proteins as potential markers for early detection of forest damage and diseases
T Nosenko, M Hanke-Uhe, PA Heine, A Shahid, S Dübel, H Rennenberg, ...
Frontiers in Forests and Global Change 4, 654032, 2021
42021
Evaluation of the neutralizing antibody STE90-C11 against SARS-CoV-2 delta infection and its recognition of other variants of concerns
L Abassi, F Bertoglio, Ž Mačak Šafranko, T Schirrmann, M Greweling-Pils, ...
Viruses 15 (11), 2153, 2023
22023
Construction of Human Immune and Naive scFv Phage Display Libraries
M Ruschig, PA Heine, V Fühner, KJK Zilkens, S Steinke, M Schubert, ...
Phage Display: Methods and Protocols, 15-37, 2023
12023
Antibody Selection in Solution Using Magnetic Beads
PA Heine, M Ruschig, N Langreder, EV Wenzel, M Schubert, F Bertoglio, ...
Phage Display: Methods and Protocols, 261-274, 2023
12023
Therapeutic antibodies with neutralizing activity against sars-cov-2 glycoprotein s
A Frenzel, K Philipp, J Kügler, M Hust, S Dübel, D Meier, F Bertoglio, ...
US Patent App. 18/000,672, 2024
2024
Mapping Epitopes by Phage Display
S Steinke, KDR Roth, R Englick, N Langreder, R Ballmann, V Fühner, ...
Phage Display: Methods and Protocols, 563-585, 2023
2023
Biomarker Discovery by ORFeome Phage Display
PA Heine, R Ballmann, P Thevarajah, G Russo, GMSG Moreira, M Hust
Phage Display: Methods and Protocols, 543-561, 2023
2023
ORFeome Phage Display Reveals a Major Immunogenic Epitope on the S2 Subdomain of SARS-Cov-2 Spike Protein (preprint)
R Ballmann, SK Hotop, F Bertoglio, S Steinke, PA Heine, MZ Chaudhry, ...
2022
Human serum from SARS-CoV-2 vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant (preprint)
M Schubert, F Bertoglio, S Steinke, PA Heine, MA Ynga-Durand, F Zuo, ...
2021
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