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Nitin H. Shirole
Nitin H. Shirole
Hope Funds Sakonnet Fellow, Dana Farber Cancer Institute/ Harvard Medical School
Verifierad e-postadress på dfci.harvard.edu
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SRSF1-regulated alternative splicing in breast cancer
O Anczuków, M Akerman, A Cléry, J Wu, C Shen, NH Shirole, A Raimer, ...
Molecular cell 60 (1), 105-117, 2015
3232015
Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization
S Senturk, NH Shirole, DG Nowak, V Corbo, D Pal, A Vaughan, ...
Nature Communications 8 (1), 14370, 2017
1562017
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions
NH Shirole, D Pal, ER Kastenhuber, S Senturk, J Boroda, P Pisterzi, ...
Elife 5, e17929, 2016
692016
Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan
AK Martínez, E Gordon, A Sengupta, N Shirole, D Klepacki, ...
Nucleic acids research 42 (2), 1245-1256, 2013
432013
TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells
D Pal, A Pertot, NH Shirole, Z Yao, N Anaparthy, T Garvin, H Cox, ...
Elife 6, e21615, 2017
392017
The evolution of TP53 mutations: from loss-of-function to separation-of-function mutants
M Miller, N Shirole, R Tian, D Pal, R Sordella
Journal of cancer biology & research 4 (4), 2016
322016
Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function
AK Martínez, NH Shirole, S Murakami, MJ Benedik, MS Sachs, ...
Nucleic acids research 40 (5), 2247-2257, 2012
272012
Correction: TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions
NH Shirole, D Pal, ER Kastenhuber, S Senturk, J Boroda, P Pisterzi, ...
Elife 6, e25532, 2017
122017
& Sordella, R.(2017) Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization
S Senturk, NH Shirole, DG Nowak, V Corbo, D Pal, A Vaughan
Nature Communications 8 (1), 1-10, 0
4
A rapid and tunable method to temporally control Cas9 expression enables the identification of essential genes and the interrogation of functional gene interactions in vitro …
S Senturk, NH Shirole, DD Nowak, V Corbo, A Vaughan, DA Tuveson, ...
bioRxiv, 023366, 2015
32015
Isolation of translating ribosomes containing peptidyl-tRNAs for functional and structural analyses
N Shirole, S Balasubramanian, C Yanofsky, L Cruz-Vera
JoVE (Journal of Visualized Experiments), e2498, 2011
32011
22 Inducible CRISPR-based Genome Editing for the Characterization of Cancer Genes
N Sachan, M Miller, NH Shirole, S Senturk, V Corbo, JB Kinney, ...
Genome Editing and Engineering: From TALENs, ZFNs and CRISPRs to Molecular …, 2018
2018
Role of Truncating Alleles of TP53 in Tumorigenesis
N Shirole
State University of New York at Stony Brook, 2017
2017
Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan*** not yet published
E Gordon, A Sengupta, N Shirole, D Klepacki, B Martinez-Garriga, ...
University of Illinois at Chicago, 2013
2013
Role of the TnaC peptide residues in the regulation of the ribosome function by L-Trp in E. coli
N Shirole
The University of Alabama in Huntsville, 2011
2011
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Artiklar 1–15